National Repository of Grey Literature 3,419 records found  1 - 10nextend  jump to record: Search took 0.20 seconds. 

Human resource management in selected business
BASTLOVÁ, Hana
The thesis aims to evaluate the characteristics and management of human resources in the selected company, an assessment of personnel activities and propose changes to the framework for improving activities in human resource management and enhancing business competitiveness.

Kidney Transplantation in Theological-Ethical Reflexion
Zárubová, Jaroslava ; Milfait, René (advisor) ; Vlková, Eva (referee)
In my diploma work i tried to valued transplant in a christiant (religious) point of view. My essay (diploma work) is consisit of (devided to) two parts - medical part, in which I have written about individual steps made before the exact transplant and I also explained what are the benefits and negatives of transplant. In the first part I also included law issues of transplant in Czech legislation, about the difficulty to donate the organ, perhaps the risk of the individual donors. I described the criteria of death from medical and ethical point of view. In a second part(teological) I have written about the value of the transplant from the ethical point of view, the religious side (reflexion) it means till when the human being is still considered as a person whose dignity has to be (needs to be) respected and whether the human autonomia is the ethical password. From the religious point of view (side) does not exist objection against volunteery transplant donors. Donor transplant is morally accepted with agreement of the donors themself and without excessive (enourmous) risks included. The purpose of th death of the individual is diagnosed (found out) first before the transplant can be donated. The possibility of the donation (transplant) abuse is the organs selling market. In the christian way the life is...

Evaluation and motivation in public administration
Vašíčková, Natálie ; Mitwallyová, Helena (advisor) ; Vláčil, Jan (referee)
The theme of the bachelor thesis is the evaluation and motivation of employees in public administration. The introductory part outlines the evaluation and motivation of employees on a general level, and then describes the specifics applicable for public administration. The practical part is focused on the evaluation and motivation systems used at selected institutions of public administration. It aims to assess these systems, suggest possible recommendations and find out whether the systems in use include modern management methods, such as evaluation interviews, competency models and regular system of employee evaluation as such. The research method consisted of interviews with human resources managers at selected institutions of public administration. Complementary information was obtained from materials created by these institutions themselves. All institutions of public administration are governed by Act No. 234/2014 Coll. on Civil Service, enshrining the evaluation of state employees. However, it depends on whether employees are evaluated formally, or if additional evaluation tools beyond the framework of the law are deployed, e.g. competency models. Officials of territorial authorities are subject to Act No. 312/2002 Coll., which does not explicitly define employee evaluation, yet employees are evaluated at many regional as well as local administration units. The results of the research survey confirmed that modern management methods are used in public administration and that the evaluation systems do not have any significant shortcomings.

Prevention of Cervical Cancer
Kafková, Simona ; Šafář, Petr (advisor)
Cervical cancer is a disease characterized by an abnormal growth of cells in the uterine cervix. It is caused by an infection with a range of high risk oncogenic human papillomavirus (HPV) and it is now accepted that more that 99 % of the cervical cancer is initiated by the HPV infection. HPV is the most common sexually transmitted viral disease. Most of the HPV infections are only temporary and human organism can destroy the infection with its own immune response. A persistent infection can lead to the malign transformation and an uncontrolled cell proliferation. There are more than 10 years between an epithelial infection and cervical cancer. Prevention of cervical cancer includes an HPV protection, an early diagnosis and a treatment. In spite of the fact that there has been enormous progress in the area of the cervical cancer prevention when vaccination against the most common HPV types was discovered, an early precancerous diagnosis through the use of the full-area screening still remains an essential precaution. The screening still needs to be provided not only to unvaccinated women but also to the immunized ones because current vaccines protect only against 80% of the oncogenic HPV types. Because of the prolonged absence of clinical symptoms in precancerous stages, the cytodiagnosis is the only method...

Influence of storage conditions on content of biologically active substances in apple fruits.
Ferdová, Jitka ; Čarnecká, Martina (referee) ; Márová, Ivana (advisor)
This study deals with antioxidants in diet and their effects on human organism. Further, it summarizes the agents affect the quality of apples in the course of long-term storage and it outlines the possibility of defence against them. In the experimental part methods of determination of antioxidant enzymes superoxid dismutase (SOD), catalase and polyphenol oxidace (PPO) in apples were introduced. The enzymes were measured in apples tissues in liquid nitrogen after 158 days in normal or modified atmosphere. In Apple the quantitative and qualitative analysis of proteins was realized. Further, some low molecular antioxidants (total phenolics, total flavonoids and vitamin C) as well as total antioxidant status were measured in frozen raw juice. This values were compared with values from apples analyzed immediately after the harvesting. Artificial inoculation with fungi was made in the last part and the fruitfulness was observed.

The use of composite graphite electrode for voltammetric determination of phenylglyoxylic acid
Šenholdová, Z. ; Navrátil, Tomáš ; Shanmugam, K. ; Barek, J. ; Žák, J.
A composite electrode prepared from graphite powder and epoxy resin was applied as a working electrode for the determination of phenylglyoxylic acid (one of the metabolites of styrene) in human urine. Cathodic differential pulse stripping voltammetry was used and optimum conditions have been found giving the limit of determination about 5 mg L-1. All results were compared with those obtained using hanging mercury drop electrode. For the confirmation of suggested mechanism of the electrochemical reaction the elimination voltammetry with linear scan was used.

Splicing of atypical introns in S. cerevisiae
Cit, Zdeněk ; Půta, František (advisor) ; Pichová, Alena (referee)
Pre-mRNA splicing is a vital process of gene expression important for all eukaryotic organisms. For the proper function of this very complex and dynamic event the presence of few specialized RNA and many proteins that hold a variety of tasks is necessary, not only inside the splicing complex itself, but also beyond this complex. The Prp45 is one of the proteins involved in pre-mRNA splicing in yeast Saccharomyces cerevisiae. Its human homologue, SNW1/SKIP, is involved in splicing but also in other crucial cell processes. The Prp45 protein was reliably reported only to participate in the second transesterification reaction of splicing. But there are also data suggesting its possible involvement in the first transesterification reaction. This work provides further evidences linking protein Prp45 with the first splicing reaction, obtained by the research of cells carrying the mutant allele prp45(1-169). Cells carrying this allele show dropped splicing and accumulation of pre-mRNAs. This thesis therefore also investigated the possible influence of Prp45 protein on the RNA export from the nucleus to the cytoplasm. But no connection between this protein and RNA transport was discovered. Keywords pre-mRNA splicing; Saccharomyces cerevisiae; Prp45; Mer1; Mud2; Prp22; Rrp6; AMA1; SNW1/SKIP

Cycling of mercury and mercury species in the environment
Finsterlová, Hana ; Diviš, Pavel (referee) ; Dočekalová, Hana (advisor)
This bachelor’s thesis deals with the role of mercury in an environment. It summarizes informations about properties of mercury and its species. The thesis is engaged in the presence of mercury in atmosphere, water, soil and sediments. It deals with individual mercury intakes into the environment, anthropogenic or natural, and it follows transport of mercury between individual components of environment. Part of this thesis is given to the accumulation of mercury and mercury species into plants and organisms. It points out the toxicity of mercury, mercury species, and their effect to human organism. In the last chapter there is a resume and description of the instrumantal methods, which are commonly used for determination mercury and its compounds.

není uveden
Bahannan, Abdulrehman ; Slavíček, Aleš (advisor) ; Dlouhá, Olga (referee) ; Slípka, Jaroslav (referee)
Endoscopic laser-assisted cordectomies classified by Remacle and Rudert (typ I-V cordectomies) comprise a vast range of procedures from simple vocal cord stripping or submucosal cordectomy (type I) through more extensive surgery (subligamentous cordectomy- type II, transmuscular chordectomy- type III) to complete (type IV) or extended cordectomies (type V) used when tumour involves the anterior commisure, arytenoid region, subglottic region etc. Endoscopic laser-assisted surgery of the larynx is usually indicated in early stages of infiltrative malignant disease of the glottic region (Tla-b, T2) or in preneoplastic conditions (laryngeal intraepithelial neoplasia - LIN I, II or III). Radiotherapy is also believed to be an equivalent type of oncological therapy for these diseases. Both surgery and radiotherapy can worsen one of the main functions of the human larynx- the human voice. Because the overall survival rates and local control rates are quite similar in both types of therapy, one should always have in mind something that is beyond the main goal of achieving radical removal of the tumour- patients quality of life (QoL) and quality of voice. It is very interesting to compare QoL and voice quality in different types of treatment. The possibility to conserve the radiotherapy for the possible recurrence...

Global Witness´s influence on forming of conflict mineral legislation
Lukeš, Jakub ; Zemanová, Štěpánka (advisor) ; Trávníčková, Zuzana (referee)
The thesis concers the issue of conflict minerals in the Democratic republic of Congo. The situation in the country has been monitored by the NGO Global Witness for decades. Human rights violation, illicit trade followed by exporting of minerals out of the country, have been supervised by militaristic rebel groups. As a result these groups have been indirectly founded by international corporations.The aim of this thesis is to evaluate the performance of Global Witness at the agenda setting of conflict minerals, including a critical assessment of legislative measures.