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Reversed discrimination in the Community contexts
Macháčková, Gabriela ; Zemánek, Jiří (advisor) ; Král, Richard (referee)
Reverse Discrimination in the Community Law Context Gabriela Machačkova The final thesis discusses the issue of reverse discrimination, which arises when nationals/products of a Member State are disadvantaged because they are subject to a national regulatory measure, while foreign (EU) nationals/products are protected from that national measure by virtue of European Community (EC) law. It examines the question of scope of EC Law, specifically focusing on the extent to which nationals of a Member State who have never exercised their Community rights can claim their rights by applying the Treaty establishing the European Community. It addresses the question of extension of the scope of EC law to cover purely internal situations in which no inter-State element is present, and to which the fundamental freedoms (free movement of goods, services, persons and capital) do not apply. First, it reviews the development of European Court of Justice case-law on reverse discrimination and situations which can be regarded as purely internal. The time frame discussed in the thesis ranges from the late 1970s until the present. Reverse discrimination and purely internal situations are analysed in terms of the examples of the Court's jurisprudence. Secondly, as Union Citizenship has been introduced by the Maastricht Treaty,...

Immunogenic cell death and its application in imunotherapy protocols
Fučíková, Jitka ; Špíšek, Radek (advisor) ; Říhová, Blanka (referee) ; Reiniš, Milan (referee)
Treatment of tumors by protocols based on combination of surgery, radiotherapy and systemic chemotherapy resulted in the improved prognosis of many human cancers. Despite the continuous introduction of new drugs and further improvements of chemotherapy protocols, it's likely that at some point chemotherapy will reach its limits and clinical efficacy will plateau. Immunotherapy has emerged as another treatment modality with the potential to contribute to further improvements in the survival. The products of advanced cellular terapies must be generated using GMP-approved reagents and number of studies have addressed the need to generate large numbers of DCs for clinical trials according to regulatory authorities and to current legislation. The rising knowledge about dendritic cells (DCs) in the immune response against tumors and the ability to prepaire DCs in vitro leaded to the establishment of immunotherapy protocols. Breakthrough studies that identified markers of immunogenic tumor cell death after chemotherapy treatment challenge the long-time perception of chemotherapy and immunotherapy as opposing and incompatible treatment modalities. My PhD thesis is a contributiont to this topic. In the first paper we identified monocyte-derived DCs that were generated in CellGro and activated using PolyI:C as the...

Výzkum a ochrana hydrosféry - výzkum vztahů a procesů ve vodní složce životního prostředí‚ orientovaný na vliv antropogenních tlaků‚ její trvalé užívání a ochranu‚ včetně legislativních nástrojů: Antropogenní tlaky na vodní ekosystémy
Výzkumný ústav vodohospodářský T.G. Masaryka, v.v.i., Praha ; Svoboda, Jan ; Kužílek, Vladimír ; Lochovský, Petr
V roce 2007 byly hodnoceny a sledovány vodní ekosystémy a jejich antropogenní ovlivnění - ovlivnění jednotlivých složek vodních ekosystémů (voda, sedimenty, biota) emisemi a specifickými polutanty. Byly hodnoceny a sledovány vodní ekosystémy a jejich antropogenní ovlivnění - časové a prostorové změny v souvislosti s antropogenními tlaky. Byl studován původ, vliv a transformace specifických polutantů ve vodních ekosystémech a jejich jednotlivých složkách, včetně možností vlivu na lidskou populaci.

The transformation of the hegemonic party: the case of Mexico
Mrvová, Lucie ; Němec, Jan (advisor) ; Paulenková, Kristína (referee)
In many countries there are several political parties in power. In some of them, however, one party is in a position of hegemony. Other political parties are prevented to exercise their real power and often act only as a parties creating an illusion of democracy in a state where it does not exist. The present thesis deals with the hegemonic party systems in terms of their origin and subsequent transition. The thesis is based on the hypothesis that changing the rules of the hegemonic party will lead it to lose its status and power. As a case study of the hegemonic party regimes serves political system in Mexico, Mozambique and Cambodia. The first chapter defines the notion of a political party, party systems theory and transition mode. The second chapter deals with the hegemonic party systems. The third chapter deals with the case of Mexico and its system of hegemonic party. Findings refute the validity of the above hypothesis, since in many countries, even after the successful completion of the transition, earlier hegemonic parties maintain their power and their electoral support is high.

Specific features of nursing care provided to members of the Church of Scientology.
MATOUŠKOVÁ, Eva
The Church of Scientology was officially registered in Los Angeles in 1954. It is present in more than 150 countries of the world, and is professed by over 8 million people. The founder of the movement is the American author of science fiction and fiction, Laffayete Ron Hubbard, who conducted research in the sphere of the human spirit, summarised in his books "Dianetics". Later on, he focused his research on spiritual beings and their abilities. This gave rise to an applicable religious philosophy - Scientology. It has not been possible to register the Church of Scientology officially in the Czech Republic so far, and therefore it acts as the civil association of "Dianetické centrum" (the Dianetic Centre). The number of its members and sympathisers in this country is not very high, reaching approximately 800 persons. Still, it is important for us to know the differences of this minority, to be able to provide its members with nursing care corresponding to their specific needs. This subject is dealt with by the multi-cultural nursing care studying cultures and religions from the point of view of nursing practice. In connection with globalisation, this subject becomes even more topical. The national, cultural and ethnic structure of the population undergoes gradual changes and the number of foreigners legally residing in the territory of the Czech Republic keeps growing. For this reason, it is important even for nurses to be prepared and have at least the minimum knowledge of multi-cultural / trans-cultural nursing care that will enable them to provide adequate nursing care respecting the specifics in question. The objective of my thesis is to get to know the specific features of nursing care provided to members of the Church of Scientology and to establish the specific features of their life style. To meet the objectives, I set five research questions. Research question 1: Do members of the Church of Scientology have specific needs when they are being provided nursing care? Research question 2: What is the attitude of members of the Church of Scientology to the health care provided in the Czech Republic? Research question 3: Do members of the Church of Scientology have specific spiritual needs? Research question 4: What attitude do members of the Church of Scientology have towards their health? Research question 5: Do members of the Church of Scientology have a specific life style? To collect data for fulfilling my research objectives and obtaining answers to the research questions, I applied the method of qualitative research. To conduct the qualitative research I used the technique of a semi-structured interview with the members of the Church of Scientology attending the Dianetic Centre in Prague. The interview contained altogether 46 questions divided into four areas, and the participants were four men and four women of different ages and different lengths of being members of the Church. The qualitative examination established the main and most distinct specific feature in providing nursing care to members of the Church of Scientology, which is maintaining silence at the time when human mind is weakened. Further, the research showed that scientologists respect physicians and do not exclude them in cases of accidents or danger of life. They normally undergo preventive examinations and do not object to being vaccinated provided that they are supplied with sufficient information. The only exception is psychiatry. Being provided with assists constitutes the only spiritual need, and the Church of Scientology has no specifics in terms of diet. This thesis may be used as a study material for general nurses and students of nursing studies, to expand knowledge in the field of multi-cultural / trans-cultural nursing care, which will facilitate providing culture-specific nursing care to members of this religious minority.

Ball-Joint Limited Heating during Accelerated Testing
Kříž, Ondřej ; Porteš, Petr (referee) ; Ramík, Pavel (advisor)
The object of this work is design model of ball joint and define boundary conditions for real condition representation as most exact as possible. Then set parameters of test in TRW-DAS, a.s. for prevention of reacceleration with change of failure mode. Summary of ball joints, their testing and accelerated tests is in the beginning of the work. Next part describes ball joint creation in Pro/Engineer, transfer to Ansys, preparing to solution, fatigue test evaluation and comparing with create model.

Differentiation And Efficiency Of Public Expenditures On Prevention And Fight Against Crime
Bernardyová, Kateřina ; Písař, Pavel (advisor) ; Řežábek, Pavel (referee)
This Bachelor thesis is concerned with the description and analysis of criminality in the Czech Republic and with related public expenditures. In the first part is an outline of common progress of criminology, individual schools and their approaches to influence crime. It brings closer view of economics dealing with the solutions to crime rates and with calculations of the social and individual crime costs. Situational analysis of crime in the Czech Republic, its sources, background and structure of supervisory authorities follows. One chapter is devoted to the female crime. The second part analyzes the correlation between the crime rates, public expenditures on crime prevention and crime repression from national and regional perspectives. The main issue of this work is the efficiency of public expenditures on the prevention and regression of the crime in the Czech Republic.

Prevention of HIV / AIDS at the grammer school
Pečánková, Tereza ; Holmerová, Iva (advisor) ; Olejník, Radoslav (referee)
This diploma thesis is trying to describe the actual situation of methods concerning the education about HIV/AIDS at the grammar school programs. It is focused rather in finding the teachers' interest to this topic, their cooperation with the experts and with the children. In the theoretical part there are the general information about the HIV/AIDS, characteristic of the illness, way of the transmission, treatment etc. This part also focuses to the description of the prevention activities of the public bodies in the Czech Republic. The practical part introduces the results of the research, which evaluate the present state of the education about the HIV/AIDS in the grammar schools. Subjective answers from the informants in combination with the known facts are forming a good general overview to the actual situation in that domain. The author within the evaluation offers several possibilities which might be a contribution to the future changes conducting to the positive developments of the current situation.

Comprehensive care of person with Alzheimer's disease
ŘEHOŘOVÁ, Andrea
The thesis deals with the comprehensive care for a person with Alzheimer`s disease. As the population gets old, also the number of people with Alzheimer{\crq}s disease has been growing. Pursuant the survey, approx. 5 % population in the age of 65 years suffers from the middle up to high degree of dementia; thereof the Alzheimer{\crq}s disease represents 50{--}60 %. Its frequency roughly doubles every five years. Alzheimer{\crq}s disease is approximately the fourth most frequent cause of all the death cases. The main goals is to find out the extent of knowledge of lay public about Alzheimer{\crq}s disease in the South Bohemian region. Hereby we mean the information about the care, possibilities of healing, symptoms and prevention of Alzheimer{\crq}s disease. In connection with these goals the H1 hypothesis was postulated: The lay public was informed of Alzheimer{\crq}s disease. For achieving the given goal, the method of questioning, the technology of the questionnaire was used. 280 questionnaires were distributed among the persons older than 18 years and they were returned in 86 %. In total, 241 questionnaires were filled in, thereof 230 were filled in correctly and also evaluated. As the most important questions for confirming or not confirming the hypothesis the author determined questions concerning the knowledge of the AD treatment, AD symptoms, knowledge of facilities, consulting centre as well as other activities for the people with AD, occurrence of AD and forms of treatment. It followed from the results that H1 hypothesis was not confirmed. Two partial targets were postulated for the given issue for the completeness sake. The first partial target was to describe the medically social issue of Alzheimer{\crq}s disease including its impact on all the spheres of the life of man: i.e. biological, psychological as well as social spheres. The second partial goal concerned the survey of services for persons with Alzheimer{\crq}s disease and their families in the South Bohemian Region. This thesis may be utilized in future as source of information about Alzheimer{\crq}s disease for the students of Faculty of Health and Social Studies in České Budějovice and for persons from the lay public who would like to learn more of Alzheimer{\crq}s disease.