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Využití opticky zachycené sondy pro studium velmi slabých interakcí na molekulární úrovni - přehled
Zemánek, Pavel ; Jonáš, Alexandr
A micron-sized dielectric particle confined in a laser trap can be employed as a probe for the measurement of forces in the range from piconewtons to hundreds of piconewtons. Thus, if a biological system of interest (e.g. DNA molecule, single myosin or kinesin molecule, cell membrane) is attached to such a probe, its mechanical and dynamical properties (elasticity, viscosity, forces associated with movement) can be studied during its interaction with the environment with unprecedented resolution. This article introduces the basic principles of the laser trapping and force measurement and illustrates on several examples the great potential of the light-based force transducer for exploiting non-invasively the dynamics of molecular systems
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The system and the financing system of psychiatric care in the Czech Republic in the period 2010-2016
Křížová, Natálie ; Lukášová, Tereza (advisor) ; Bartůsková, Lucia (referee)
The bachelor thesis focuses on mental health, which is becoming a socio-economic problem these days. Since there is a constant prevalence of patients with mental illnesses and thus an increase of a burden in the economic system, this work explains the system of psychiatric care, which is crucial for the future development of mental health of Czech population. Based on the analysis of the issue it is evident that the effort to manage the care system to community care will do not contribute to the reduction of treatment costs, but on the other hand, will facilitate the accessibility to psychiatric facilities for patients. The funding of psychiatric care is not based on the national health system, which influences the direction of a large part of the funds for treatment in psychiatric hospitals.
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Fiscal rules in selected EU countries between 2004-2015: sensible method for consolidation of public finances or fad of politicians?
Veselý, Lukáš ; Strejček, Ivo (advisor) ; Chmelová, Pavla (referee)
The subject of fiscal rules is very topical issue. The rise of public debt in certain developed countries resulted in what is sometimes called "debt crisis". Debt of those countries which is higher than their annual gross domestic product is viewed as unpayable by some economists. The main objective of this thesis has been to prove or disprove hypothesis that the fiscal rules studied in this paper are an effective solution for public finance consolidation. This verification was based on the analysis of fiscal rules functioning in selected countries between 2004 and 2015. As per results of analysis the paper aims to give recommendations for the Czech financial constitution proposal. The actual results of inquiry proved the hypothesis. Well-chosen fiscal rules are the right way towards fiscal consolidation, provided they are observed. Fiscal rules making thus requires an emphasis to be placed on the well-formulated exit clauses altogether with prospective sanctions. The current Czech financial constitution proposal is built on the correctly picked fiscal rule type, although the reference value lacks economic sense and it would not lead, with a high degree of probability, towards fiscal consolidation.
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Tax and legal issues of real-estate business in Austria
Banctel, Kristýna ; Filipová, Vladimíra (advisor) ; Drozen, František (referee)
The purpose of this study is to compare tax and civil-law issues concerning property business in Austria and in Czech Republic in 2016 and to investigate the efficiency of the current legislation against the real estate bubble. The theoretical part of this study contains selected demographic and price statistics concerning real estate in both countries and focuses on the description of the existing law currently in effect in both compared countries. The practical part analyses tax and transactions costs that concern property trading and a comparison of possibilities of amortisations and rentability of a rented flat in both countries.
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The impact of the economic cycle to finance the defense of the Czech republic in years 2004-2014
Heres, Ondřej ; Chmelová, Pavla (advisor) ; Strejček, Ivo (referee)
This bachelor work examines the impact of economic performance on financing the defense sector in the Czech Republic in the years 2004-2014. The main questions are whether this influence is clear and the extent to which is essential for funding this sector. The work also provides a basic overview about development and structure of the Ministry of Defence budget in these years. The theoretical part contains theories of business cycle and public sector and briefly introduces the basic institutions that are tasked to provide a defense. The analytic part analyzes the expenditures and revenues of the Ministry of Defence and assesses their mutual influence and simultaneously the influence of GDP on these indicators. To compare with previous findings, the GPD growth rate and the growth rate of defense expenditures in selected countries of NATO are analyzed in brief in the last chapter. While findings based on data from the Ministry of Defence have rather anticyclical development of defense expenditures, in selected countries of NATO, the development is more procyclical. It highlights the very ambiguous impact of the economic cycle on expenditures in the defense sector.
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Supervision of volunteers in nonprofit organizations
Beerová, Michala ; Kopecký, Martin (advisor) ; Šerák, Michal (referee)
The theme of the presented bachelor thesis is the process of supervision and the volunteerism. Volunteering is an important subject in today's society and essentials workforce in social work. The aim of this work is to focus on the non-profit sector and try to describe it. Furthermore, there is an explanation of the position of volunteers in these organizations and supervision in social work. Supervision is one of the managerial function in non-profit organizations, which is widely and long-term applied. The thesis wants to show basics, consequences and benefits of volunteer's supervision. Providing supervision is one of the main objectives of the organization to support staff or their volunteers. This bachelor thesis explores volunteering and supervision in two countries, the Czech Republic and Sweden. This thesis compares two different approaches, based on history of these two countries. Volunteering and supervision are very interesting features of the non-profit organizations. The practical part of this thesis comprises from qualitative investigation of different nonprofit organizations. The organizations were interviewed to get information about the purpose of the volunteering, educational potential of supervision and the current situation of volunteer supervision there. The aim of this investigation...
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The Financial Literacy of Senior Citizens
KOCANDOVÁ, Soňa
This bachelor thesis focuses on the elderly and their financial literacy. This thesis is divided into two main parts, theoretical and practical. The theoretical part defines actual knowledge about this theme and is divided into two chapters an introduction to issues about ageing and financial literacy. The author talks about seniors, demographic situation of ageing, forms of living, secured retirement in old age and financial literacy. The author also paid attention to presentations of products. The practical part includes the actual implementation of research and interpretation of the data is divided into four chapters. The first chapter is devoted to the work and objectives of the research questions. The aim is to map the awareness of seniors in the effective management of their finances. The author also set partial research questions and the main research question is whether seniors are aware of their financial security. The second chapter researches methodology, which includes a qualitative research method of semi-structured interviews. The interviews are divided into three fields. The first is introductory information, the second field is financial literacy and the last field is presentations of products. The research methodology also characterizes the surveyed group, which consists of ten respondents over sixty five years old and lives in the Trebon region. In the third and the most extensive chapter there are the results and data. The elderly mostly answered in a different way however in some ways they agreed. The last chapter evaluates results and draws the author´s opinion. It has been found out that respondents have diverse interests and hobbies in retirement and they participate in them very actively. The income of the respondents is satisfactory to those who live in a household of two members. The financial situation has been described as good as well as average. Fifty percent of the respondents have experience with credit and only two of them create the budgets. The last set of questions was about demonstrations of goods and majority of the respondents have some experience with them. The last chapter is the conclusion which summarizes the information obtained. The main research question is whether seniors are aware of their financial security and the results show that all respondents have an over view of their finances. The elderly people orientate themselves well in money matters and they can optimally manage their money. They are vigilant in connection with credit and loans. They rather save money and they say that they do not buy anything when they do not have money. It is good that they are informed and can thus better resist the pitfalls that exist in this world, whether we like it or not. This thesis might be useful in practice for the elderly who want to try to draw up the budget. It can make a contribution to higher awareness about dangers of presentations of products.
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Míry podobnosti pro nominální data v hierarchickém shlukování
Šulc, Zdeněk ; Řezanková, Hana (advisor) ; Šimůnek, Milan (referee) ; Žambochová, Marta (referee)
This dissertation thesis deals with similarity measures for nominal data in hierarchical clustering, which can cope with variables with more than two categories, and which aspire to replace the simple matching approach standardly used in this area. These similarity measures take into account additional characteristics of a dataset, such as frequency distribution of categories or number of categories of a given variable. The thesis recognizes three main aims. The first one is an examination and clustering performance evaluation of selected similarity measures for nominal data in hierarchical clustering of objects and variables. To achieve this goal, four experiments dealing both with the object and variable clustering were performed. They examine the clustering quality of the examined similarity measures for nominal data in comparison with the commonly used similarity measures using a binary transformation, and moreover, with several alternative methods for nominal data clustering. The comparison and evaluation are performed on real and generated datasets. Outputs of these experiments lead to knowledge, which similarity measures can generally be used, which ones perform well in a particular situation, and which ones are not recommended to use for an object or variable clustering. The second aim is to propose a theory-based similarity measure, evaluate its properties, and compare it with the other examined similarity measures. Based on this aim, two novel similarity measures, Variable Entropy and Variable Mutability are proposed; especially, the former one performs very well in datasets with a lower number of variables. The third aim of this thesis is to provide a convenient software implementation based on the examined similarity measures for nominal data, which covers the whole clustering process from a computation of a proximity matrix to evaluation of resulting clusters. This goal was also achieved by creating the nomclust package for the software R, which covers this issue, and which is freely available.
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The nutritional importance of polyphenols in berries
MARTANOVÁ, Anna
People's nutrition is inseparable part of our lives. We could include substances, that we know are healtful, to our food. If we don't have enough of the substances, we can see negative effects on human organism. The substances are named micronutrients and vitamins. We could enrich a diet with substances that we think are healthy, but their deficit doesn't case pathological symptoms. Food which we put to this category is possible to name as function food. Function food contains substances which have positive effect on our health. One of the substances are polyphenols. This issue is very interesting for me, because polyphenols are compounds that are among others particulary found in berries, especially in blueberries. Blueberries are berries that are widespread throughout the world. One of the best sources of blueberries is also Sumava, where I come from and where blueberries are well connected. The first part of my thesis is about the functional foods and ingredients that make these foods Functional foods. Ordering: probiotics, prebiotics, synobiotiks, micronutrients, fytochemiks and polyphenols. Farther the first part deals with berries, specializing in blueberry and its properties and composition, which can have a positive impact on human health.In the second part there were two objectives of the work. The first aim of my study was to determine the diet, which includes foods that contain the optimum intake of polyphenols, equivalent to 120 ml of fetal native blueberries. Polyphenols are that part of blueberries, which make them so special. In the diet were preferentially embedded short dishes that have undergone heat treatment. Analyses of polyphenols in foods and beverages I got with the program GEOMED hospital Ceske Budejovice, Inc., Department of Clinical Pharmacology. Results polyphenol content were performed by HPLC. The content of polyphenols in native blueberries was laid as equal to 1 and the contents examined further product was then expressed as a multiple or ratio of the native blueberries. I take into account all these factors when drawing up the model menu. Another aim I have set is to map products in which the content of polyphenol is beneficial. There is a high number of products with blueberry flavour on the market. The content of blueberries, however, is often negligible. The surprising result was the polyphenol content in lemonade Toma, whose relative value ug / ml is 2.59 when compared with the native blueberry, which is placed as equal to 1. After the development work, in which I obtained information from the literature search, the sales network and the Department of Clinical Pharmacology, Hospital Ceske Budejovice, I would like to say that blueberries are an important source of polyphenols and that a diet which will include daily equivalent of receiving polyphenols, may not in any way differ from a regular rational diet. Not even cooking the dish precludes putting together this diet because blueberries are relatively stable against temperature changes. Inclusion of such a diet in the catering equipment could bring a positive impact in the future, especially for older people by improving memory function and balance.
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The tax system reduces motivation to return to work among mothers with young children: recommendations and evaluation
Šatava, Jiří
In the Czech Republic, the overall taxation of work, i.e individuals' income tax together with social security and health insurance contributions, places a heavy burden even on the relatively low earnings of so-called second earners in households, i.e. partners with lower earnings. These peoples' work activity is, however, generally very sensitive to the level of taxation. A large group of these earners is made up of mothers with young children. Mothers who are the second earner in their household are subject to a participation tax rate (PTR) up to 30 % higher than their partners, and yet a higher PTR results in lower motivation to work. Women with children and low earning potential are subjected to the highest PTRs in comparison with their partners.
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