National Repository of Grey Literature 24,283 records found  1 - 10nextend  jump to record: Search took 0.71 seconds. 

Role of adipokinetic peptides in control of insect anti-stress reactions
Kodrík, Dalibor
Adipokinetic hormones (AKHs) control predominantly insect metabolism, but are involved also in a number of other activities. Recently, it was proven that AKHs participated also in the activation of antioxidant protection mechanisms: they increased a level of reduced glutathione and additionally, modulated the activity of catalase that reduces hydrogen peroxide to water and oxygen. It has also been found that AKHs participated on antistress reaction elicited by insecticides and increased the lethal effect of the insecticides alone. The results show that AKHs provide an initiation of the complex antistress response that involves both biochemical and physiological protective mechanisms.

Critical evaluation of Šik s reform
Šrámek, Ondřej ; Szobi, Pavel (advisor) ; Dufek, Pavel (referee)
The thesis deals with the so called Šik s reform, which was a reform, that tried to implement certain elements of market economy in the centrally planned economy of Czechoslovakia in the sixties of the twentieth century. Firstly the thesis describes the course of the reform, when the importance of the central plan was significantly reduced, the position of enterprises was strengthened and the price system was rebuild. Lately the thesis examines and compares opinions on reform and new economic system of foreign and domestic experts. The goal of the thesis is to discover mistakes and imperfections of implementing of new systém, which could endanger its functioning.

Marketing Plan of MAGICAM HD SOLUTIONS, Ltd
Pařízek, Aleš ; Hesková, Marie (advisor) ; Harantová, Monika (referee)
The main goal of the bachelor study is to create functional marketing plan for year 2017 that is consistent with the existing long-term marketing strategy. This thesis is created for use in business company MAGICAM HD SOLUTIONS Ltd. The core of the thesis is devided into theoretical and practical part. The first part laid the foundations basis of the terms used in the marketing planning, it is described the relationship marketing strategy, plan and tactics and role in the functioning of the marketing plan of the company. The second part contains the characteristics of the company, the analysis of external and internal factors affecting the company, SWOT analysis, setting goals and designing procedures by which the company will achieved set go-als. The practical part also contains specific steps in the action programs and timetable. Finally the thesis evaluates individual parts and contribution to the company.

The analysis of price elasticity of demand for beer
Hromadníková, Kateřina ; Mirvald, Michal (advisor) ; Babin, Jan (referee)
The thesis analyses price elasticity of beer demand. Hypothesis about inelastic demand is tested first for nationwide level and then on data of specific brewery. Elasticity was determined by regression analysis, specifically by ordinary least squares with all variables expressed in logarithmic form. Consumption of beer is the endogenous variable and price of bottled beer (price of one hectoliter of beer in case of brewery), average gross income and price level are in the role of the exogenous variables. The hypothesis about inelastic demand was successfully proved. Price elasticity estimates range from -0,66 to -0,2. In case of specific brewery price was not significant. On the other hand, average gross income seems to be the significant determinant. According to income elasticity beer seems to be luxury good in case of specific brewery and necessity in case of nationwide level.

The influence of selected ECJ judgements on the forming of common commercial policy of EU
Vicherek, Ondřej ; Bič, Josef (advisor) ; Procházková Ilinitchi, Cristina (referee)
The goal of my diploma thesis is to describe the influence of ECJ decision making on the common commercial policy ("CCP") of EU. Specifically my thesis examines what factors influence ECJ decision making about direct effect of trade agreements implementing CCP. These factors are applied on several treaties, where the court has not yet decided on their potential direct effect and on a present case at ECJ on direct effect of WTO treaties. With regard to the goal of my thesis an important part of my thesis deals with the development of ECJ decision making. Methods applied in my thesis are analysis and comparison of selected judgements that influence the CCP of EU. After proper analysis I found out that the main motiv behind ECJ decision making is that, if the negotiating position of EU is to be deteriorated, the ECJ is likely to find that the treaty does not have direct effect. Other factors are of secondary character. Examining the influence of decision making of ECJ on direct effect of trade agreements is important, because the role of ECJ influences the legal certainty of subjects about direct applicability of international trade treaties.

Serverless single page application in JavaScript
Zikmund, Marian ; Pecinovský, Rudolf (advisor) ; Suchan, Vladimír (referee)
The goal of this thesis is to design and develop a framework for building modern single- page application in the JavaScript programming language and describe this approach to development. The work also contains the documentation for a more comfortable use and customization. The content is divided into eight chapters. The introduction is followed by the retrieval of information resources, including the specifics of the JavaScript programming language and explanation of the formation of single-page application. The description of the basic principles of their functioning, motivation and justification, when and why this approach is appropriate is also included. The work is primarily focused on the issue of single-page application, for which the use of the JavaScript programming language is crucial. For this reason, this work provides a whole chapter about this programming language, also including a description of its history and role in the context of others. Below are the common characteristics of single-page applications frameworks, built on top of the library ReactJS, whose formation is engaged in the following chapter. The developed framework also contains the user guide. The practical outcome of this work is an open source framework for creating serverless single-page applications, which is due to its architecture and documentation appropriately adaptable.

Speculation on oil markets and its impact on commodity's price
Melcher, Ota ; Taušer, Josef (advisor) ; Baláž, Peter (referee) ; Müller, Štěpán (referee)
This study aims to analyse the precrisis period on the oil markets with a primary objective of assessing the role of speculation in the commodity's price development and its volatility. First it depicts the rapidly increasing speculative activity on the futures market together with the parallel oil price surge. The speculation is initially proxied by non-commercial traders' positions and subsequently quantified by Working's T-index. The paper then uses speculative traders' positions and both spot and futures prices to test for Granger causality within the framework of VAR models. For the sake of consistency it also evaluates causal links between speculation and inventories level. Further the study investigates the speculation impact on volatility of oil prices by employing various approaches in volatility quantification including GARCH models. Contrary to expectations we find that the speculatio's impact on both prices and their volatility is rather insignificant. In the last chapter we therefore seek for an explanation of the oil price developments by examining the market fundamentals. The interaction of supply and demand finally gives substantial evidence for understanding the price developments in the precrisis period.

Determinants of Industrialization in sub-Saharan Africa and Possibilities for their Development
Sejkora, Jiří ; Jiránková, Martina (advisor) ; Šaroch, Stanislav (referee) ; Fárek, Jiří (referee) ; Adamcová, Lenka (referee)
Sub-Saharan economies need structural changes that would enhance their productivity, increase economic growth and development. In this regard, industrialization plays a key role. Using regression analysis, the aim of this dissertation thesis is to identify main factors (determinants) of industrialization in sub-Saharan Africa. The results indicate that infrastructure and economy size (measured by population size) represent main determinants of industrialization in the region. The thesis also deals with possibilities for development of those determinants. Case study of infrastructure development in Mauritius emphasizes privatization, cooperation with external subjects etc. Negative consequences of small economy size can be overcome by preferential trade agreements (under certain circumstances), as shown by analysis of the three smallest economies in the region.

Immunological profile of patients with multiple sclerosis
Šubjak, David ; Fišerová, Anna (advisor) ; Růžičková, Šárka (referee)
Immunological profile of multiple sclerosis patients Abstrakt Multiple sclerosis is an autoimmune neurodegenerative disease affecting predominantly the white matter of the CNS and the spinal cord. The mechanism of disease progression is not yet fully understood. In this study we focused on a comparison of selected immunological markers between patients with multiple sclerosis who were naïve newly diagnosed, subsequently treated with Avonex (IFNβ1a) and healthy donors. The T cells (particulary cytotoxic CD8+ T cells) are the major population involved in pathogenesis of MS causing the demyelization of axons. Subpopulation of CD161+ Th cells has a potential to be very important in this process. We focused on the role of NK cells phenotype and function in autoimmune response of patients and their changes during the therapeutic intervention. Using flow cytometry we analyzed the distribution of NK, NKT, T cells and monocytes with special regard to the expression of CD161 and NKG2D molecules on their surface. We observed increase counts of CD161+ cells in subpopulations NK CD56bright , NK CD56dim , Th, Tc CD8bright , Tc CD8dim and decrease counts of NKG2D+ cells in subpopulations NK CD56bright , NK CD56dim , NKT, Th, Tc CD8bright , Tc CD8dim and monocytes. The decreased cytotoxic activity of NK cells in naïve MS...

Role of UNHCR in case of asylum seekers, refugees and stateless persons – the case study of Turkey
Unzeitigová, Klára ; Novotná, Markéta (advisor) ; Kuchařová, Alžběta (referee)
Inspired by the Kratochvíl, Cibulková and Beník´s model of actorness, the thesis explores the framing power of UNHCR. The critical discourse analysis introduced by Norman Fairclough is applied in order to analyze the textual, contextual and sociocultural dimension of the UNHCR framing power. The case of Turkey was chosen for this study due to the current situation and the fact that Turkey is one of the biggest hosting country in the refugees´ crisis. Through the critical discourse analysis, the thesis explores whether UNHCR is considered as a framing actor in the case of asylum seekers, refugees and stateless people in Turkey. The analysis shows that UNHCR is globally respected and takes important part in the issue. However, not all of the international organizations refer to UNHCR as the lawmaker and the initiator of debates in the issues mentioned above.