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Analysis of the Economic Development of BRICS Countries in 2007–2015
Berka, Kryštof ; Procházka, Pavel (advisor) ; Dyba, Karel (referee)
The aim of the bachelor's thesis is economic development assessment among and within BRICs countries in the context of developed world during 2007-2015. Based on yearly panel data, an analysis for following macroeconomic indicators was carried out: gross domestic product, inflation rate, unemployment rate, current account on the balance of payments, exchange rate. The profound analysis of selected indicators is instrumental in the comparison of member states and is supplemented by the comparison of BRICs and G6. Based on its evidence, I come to a conclusion that the BRICs as a whole succeeded in establishing as a strong global actor. That has been achieved with the help of global financial crisis, but also with regard to the economic policy implemented in 2007-2015. As a result, GDP of BRICs in terms of GDP of G6 achieved stable growth rate leading to its increase by 52 %. Besides providing main findings, outcomes of this thesis enable to identify main weaknesses and strengths of BRICs economies affecting the prospects for continuance of stable economic growth.
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A possible approach for assessment of general singular stress concentrators on the basis of linear elastic fracture mechanics
Náhlík, Luboš
This paper studies a stress distribution around a general singular stress concentrator tip on the basis of linear elastic fracture mechanics. A procedure for development of stability criteria of general singular stress concentrators is shown. Three different methods for determination of an essential critical stress for crack propagation from the stress concentrator tip are introduced. Each of used method is useful for different mechanism of crack propagation. The described procedures are based on three dissimilar physical basis: on the energetic ground – the generalized strain energy density factor is mentioned, on the failure stress of material grain ahead of concentrator tip and on the size of plastic zone in front of concentrator tip. The numerical results can contribute to better understanding of general stress concentrators behaviour and can be used for design of engineering structures with mentioned type of stress concentrator
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Balance-related exercise as a preparation to cross-country skiing practice in visually impaired children
Chmelíčková, Hana ; Daďová, Klára (advisor) ; Levitová, Andrea (referee)
Title: Balance-related excercise as a preparation to cross-country skiing practice in visually impaired children. Objectives of the Thesis: The goal of this thesis is to test the possibilitiy of implementation of selected balance- related excercise in visually impaired children. Method: The testing pool consisted of six pupils attending the Special school for Visually Impaired Children between 14 and 15 years of age. Over the period of ten weeks, selected exercise geared towards the cross-country skiing was practiced with these students. The research method applied to measure students' indicators of balance before and after the excercise was an assessment of standing stability at the Footscan pressure table, as well as a walking test in terrain with blinded eyes. Results and Conclusions: This research has indicated the possibility of physical intervention in form of balance- related practice as part of the preparation before the cross-country skiing season begins. It has proven that selected balance-related excercise can be applied with no limitations during the physical education classes for visually impaired pupils. After the physical intervention, the majority of tested individuals showed improvements in their indicators of dynamic balance, as proved by the walking test in terrain with blinded...
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Initial stages of fatigue failure of polycrystalline materials
Man, Jiří ; Petrenec, Martin ; Obrtlík, Karel ; Polák, Jaroslav
Geometry of persistent slip markings (PSMs) formed during cyclic loading of polycrystalline stainless steels and superalloy was studied using atomic force microscopy (AFM) and high-resolution scanning electron microscopy (SEM-FEG). Internal dislocation structure was investigated using transmission electron microscopy (TEM). Persistent slip bands with dislocation structure corresponding to the cyclic strain localization were identified and correlated with PSMs observed on the specimen surface.
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Analytical Evaluation of Biologically Active Substances by Chromatographic Methods
Pasáková, Ivana ; Sochor, Jaroslav (advisor) ; Nobilis, Milan (referee) ; Holčapek, Michal (referee)
Introduced dissertation thesis deals with the development and validation of the chromatographic methods for analytical evaluation of selected biologically active substances. HPLC coupled with UV and MS detection was chosen for determination of analytes, because of the dominant role of the HPLC in pharmaceutical analysis. The theoretical part is focused on the theory of chromatographic methods and topics of the experimental work. At first, summary of all the chromatographic methods is briefly introduced and subsequently, the most common analytical method HPLC is described in details. The next part deals with the mass spectrometry. Thank to its high sensitivity and ability to provide structural information about the analytes, MS became an indispensable tool not only in modern pharmaceutical analysis. Besides MS theory and instrumentation, its applications and new trends are also mentioned. Last chapters deal with the transdermal application of drugs, specifications of antiretroviral therapy and especially they provide basic information about the physical - chemical and biological properties of analysed substances. The experimental part is consisted of the original research papers with appropriate comments divided into two thematic sections. The first one is composed of three papers focused on analytical...
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Evaluation and analysis of the financial strategy of the company Linea Nivnice as
Juhászová, Bibiána ; Machek, Ondřej (advisor) ; Štamfestová, Petra (referee)
The aim of this thesis entitled "Evaluation and analysis of the financial strategy of the company Linea Nivnice as" is to analyze the financial situation of the company Linea Nivnice between 2009 and 2013. The work is divided into theoretical and practical part. The theoretical part describes the theoretical background, methods and procedures for analyzing financial strategy as horizontal and vertical analysis, balance rules, ratios, economic value added, creditworthy and bankruptcy models, PEST analysis, SWOT analysis, Porter's five forces model and comparison with the industry . The practical section provides the methods and procedures applied by the company Linea Nivnice Conclusion contains a summary of the most significant identified knowledge and assessing the financial position of the company.
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Problems of renal tumours in patiens with terminal stadium of renal failure
Ürge, Tomáš ; Hora, Milan (advisor) ; Novák, Jaroslav (referee) ; Zachoval, Roman (referee) ; Morávek, Petr (referee)
Objective: Risk of renal carcinoma is minimal 10 x higher in group of patients in terminal stadium of renal failure (end stage kidney disease - ESKD). We have only some information about chromosomal changes in renal tubules, from which rise renal carcinoma, and about pathogenesis of renal carcinoma, which seems to be different from carcinoma in common population. Aim of the study: In clinical part we valorize characteristic signs of renal carcinoma in ESKD by using of statistic methods. In experimental part we can explain pathogenesis of this carcinoma by analysis of selective chromosomal aberations. Material, methods: In 2000 - 2007 were 184 patients with ESKD in care of transplant centre and nephrologic ambulation of Faculty hospital Plze_. In 15 patients we diagnose renal carcinoma. In this group we valorize: age, gender, causation of renal failure and dialysis duration. Age, gender and type of renal carcinoma we confront with carcinoma in common population. In experimental part we valorize numerical aberations in chromosome 7, 17 and Y of tubular epithelium using fluorescent hybridization in situ (FISH). Results: We have 15 patients in average age 55.7 ± 11.5 years, long of during dialyzation was 78 ± 54 months. We do not find dependence between causation of renal failure and genesis of renal...
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Freezing technology of bull sperm in relation to its survivability and fertilization ability
Doležalová, Martina ; Stádník, Luděk (advisor) ; Jiří, Jiří (referee)
The aim of optimalization the insemination doses production is to provide the highest fertilization ability of spermatozoa during the demanding proces of processing fresh semen and its subsequent cryopreservation. Temperature changes causes spermatozoa damage during the cooling and freezing. Spermatozoa is exposed to cold shock and many others limiting factors, which leads to cell death and therefore to decline of fertilization ability of thawed insemination doses. For increasing spermatozoa resistance, exactly the plasma membrane resistance against cold shock was fraction of egg yolk LDL cholesterol (low density lipoprotein) at various concentrations into the comercially produced diluents added. It is believed that LDL acts possitively to plasma membrane and helps to maintain the fertilization ability of spermatozoa after thawing. Following step in the proces of insemination doses production is slow cooling of diluted semen and equilibration, when the straws are store at cooling box for 30 minutes to 240 hours. This period is necessary to penetrate of certain diluent components into the spermatazoa also maintain the balance between their intracellular and extracellular concentration. Also important is subsequent freezing temperature gradient of insemination doses. The most suitable freezing method is based on computer controlled temperature decline in freezing chamber which allows the precise control of ice crystals formation that could tear and kill the cell.
During 2012 to 2016 was repeatedly collected semen from the group of breeding bulls (n = 27, Holstein and Czech Fleckvieh breed) at AI centre. Semen which fulfill the standard entrance conditions in first step was evenly into several parts divided. For dilution the three types of comercially diluents AndroMed, Bioxcell and Triladyl with and without LDL addition were used. Into the diluents AndroMed and Bioxcell the concentration of LDL 4 %, 6 % and 8% into the dilent Triladyl 6 %, 8 % and 10 % was added. Diluted semen was filled into the glass capillares with volume 0,1 ml and temperature +4 °C. Subsequently the sample was placed to cold bath (0°C) for 10 minutes. Then the volume of capillare with physiological solution (37 °C) was mixed and for next 120 minutes was incubate. The effect of cold shock to proportion of live spermatozoa was evaluated by using Eosin and Nigrosine staining technique during heat test of spermatozoa survivability after spermatozoa heating and after 120 minutes of incubation.
The more suitable semen diluents which provide the higher spermatozoa resistance against cold shock were AndroMed and Bioxcell. Together the possitive effect of LDL addition into the diluents to lower decrease of proportion of live spermatozoa during heat test was found (P<0.05). The most suitable LDL concentration which had a favorable influence at spermatozoa resistance against cold shock was 6 % in diluent Bioxcell. Values of the proportion of live sperm were higher at the beginning of the heat test (+1.31% to + 3.2%) and after 120 minute incubation (+5.82% to +8.41%) compared to other diluents with and without addition of LDL.
In the next step the process of equilibration was optimized, is an important part of insemination doses production. The effect of the length of equilibration for subsequent fertilization ability of spermatozoa was evaluated using spermatozoa motility based of CASA and proportion of live spermatozoa after thawing and during heat survival test lasting 120 minutes (37 ° C). Suitable semen was diluted by comercially used diluent AndroMed based on soya lecithin, filled into the straws (0.25 ml), cooled and equilibrated in cooling box for 30, 120 and 240 minutes and freezed in programmable freezing box applying four types of freezing curves differing in temperature rate decline. There was used standard and by producer recommended 3. phase freezing curve, then 2. phase freezing curve, and 3. phase freezing curve with slower as well as rapid decline of temperature rate in freezing chamber, compared with standard freezing curve. The highest spermatozoa motility was found using 240 minutes of equilibration by +2.72% and +4.58% compared to other lengths of equilibration (P <0.05 to 0.01). The highest proportion of live spermatozoa was found using 120 minutes of equilibration (+6.87 % and +8.68 %). The highest average spermatozoa motility during heat test after thawing was achieved by using 2. phase freezing curve (from +2.97% to +10.37%, P <0.05), also in the proportion of live spermatozoa (from + 4.37% to +8.82%, P <0.01). When evaluating interaction between the length of equilibration and freezing curve (standard 3. phase and 2 . phase freezing curve), the highest average spermatozoa motility and proportion of live spermatozoa using 240 minutes of equilibration by both freezing curves was reached, there was no statistically significant differences. As well as, in all evaluated parts of this study the individual differences between ejaculate of bulls and within semen from one bull (P <0.05) as secondary effect were found.
To maintain good fertilization ability of semen during cryopreservation is necessary to increase the spermatozoa resistance against cold shock using addition of correct concentration of LDL into the commercially used diluents AndroMed and Bioxcell. Subsequently the fertilization ability of insemination dose is influenced by cooling, the length of equilibration and freezing. The length of equilibration 120 minutes and more as well as gentle way of freezing according to freezing curve, which ensures a gradual decrease of temperature in freezing chamber provided the higher average spermatozoa motility and proportion of live spermatozoa.
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Mam-Machina-Systems and their Reliability
Jurčík, Petr ; Skřehot, Petr (referee) ; Havlíková, Marie (advisor)
The point of this work is to describe and analyse human and technical reliability inside a man-vehicle system. The reliability of whole system is given by partial reliabilities of technical sub-systems and reliability of a man like a human operator. Human operator influences security and reliability of whole system by his activity and servicing of equipment. It is necessary to monitor and evaluate this activity in the analysis of security of technical systems. By the evaluation of human reliability people come out of the whole probability analysis of security. Inside the man-vehicle system the vehicle is operated by the driver and therefore influence of human operator is totally fundamental for the total reliability of this system. Graphic fault tree model shows different combinations of equipment failures and people failures which can lead to the accident.
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