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Manifestations of facial asymmetry in young adulthood: the relationship between asymmetry of facial expressions and manifestations of brain laterality
Hřebcová, Eliška ; Velemínská, Jana (advisor) ; Měšťák, Jan (referee)
This thesis focuses on assessing longitudinal changes in facial asymmetry of both neutral expression and various facial expressions in adolescents and young adults aged 15 to 18 years and their relation to handedness. Shape changes were evaluated in 30 girls and 27 boys of which 3 girls and 2 boys were left-handed. For the analysis, 3D geometric morphometry applied to 3D facial scans was used. The scanning itself took place on three different occasions with a 1-year gap between them. A total amount of 1440 facial scans were taken and processed, while 453 of those were used for the analyses. The output of those analyses are colour maps visualizing changes in facial shape. Right-handers were assessed as a mean group, while left-handers were assessed only as individuals, due to their low numbers. The results of longitudinal assessment in right-handers show very similar trends between boys and girls. Protrusion in right side of the forehead and right side of the nose and maxilla was observed, as well as right-sided protrusion of lower lip and mandible in later ages. Left-sided protrusion of angulus mandibulae was observed in both sexes. An almost complete absence of the forementioned forehead protrusion was observed in all left-handers. Protrusion was more often allocated on a left side of the nose....
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Longitudinal observation of parameters of dymanic postural stability on patients with sclerosis multiplex in terms of biological treatment
Krčíková, Barbora ; Vomáčková, Helena (advisor) ; Maršáková, Kateřina (referee)
Author: Bc. Barbora Krčíková Supervisor: PhDr. Helena Vomáčková, Ph.D. Title: Longitudinal observation of parameters of dymanic postural stability on patients with sclerosis multiplex in terms of biological treatment Objectives: The aim of this thesis is to describe the postural movement behaviour (independent of therapeutic intervention) in patients with multiple sclerosis referred for biological treatment. Methods: The study used longitudinal monitoring of fatigue and quality of walking in probands (n=2, female, ages 24 and 52) using the Multiple Fatigue Impact Scale (MFIS) and the Multiple Sclerosis Walking Scale-12 (MSWS-12) questionnaires, Longitudinal follow-up of changes in selected parameters of dynamic postural stability obtained on the NeuroCom SMART EquiTest System (Limits of Stability) and longitudinal follow-up of mobility tests using the T25FW (Timed 25 Foot Walk), 6MWT (6-minute Walk Test) and 5STS (5-repetition sit-to-stand test). Testing was conducted in the Applied Kinesiology Laboratory of the Department of Physiotherapy, UK FTVS. Each proband was asked to complete subjective questionnaires at each measurement, after which measurements were performed on the NeuroCom SMART EquiTest System using 7 protocols - Sensory Organization Test, Motor Control Test, Adaptation Test, Weight...
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Multiple Sclerosis - Neuropsychological markers for monitoring disease activity
Friedová, Lucie ; Uher, Tomáš (advisor) ; Holštajn Zemánková, Petra (referee) ; Libertínová, Jana (referee)
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that generates a wide range of clinical symptoms. These include cognitive impairment, a set of symptoms closely associated with the quality of life, which also serves as one of the most important predictors of limited ability to work. This doctoral thesis presents the output from four studies divided into three areas focusing on neuropsychological markers in connection to other manifestations and effects of MS. The first researched area is the link between speech characteristics and the information processing speed by patients with MS. Our study has proven a profound association between lower speed of articulation and below-average performance in terms of information processing speed. We have proven that acoustic quantitative speech analysis has the potential to identify patients with below-average cognitive performance. Another goal of this doctoral thesis was to ascertain the predictive value of serum neurofilament light chain levels in recently diagnosed patients with MS for the development of cognitive disorder within nine years of observation. During the period of observation, we uncovered only a loose link between high levels at the onset of the disease and the deterioration of cognitive functions in...
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Facial development in children 6 to 12 years old: longitudinal study
Tošovská, Hana ; Velemínská, Jana (advisor) ; Zedníková Malá, Pavla (referee)
This study is based on evaluative longitudinal data of facial development in a group of children from 6 to 12 years. The research used three-dimensional models of the faces of 18 girls and 15 boys that were scanned at yearly intervals. These models were used to follow development of the face and its particular areas including analysis of variability (PCA). Developmental changes were observed for each gender separately as well as for the development of sexual dimorphism. Results were visualized by using superimposed color maps of average faces of a particular age group and maps depicting the statistically significant differences in individual areas. The presented data exhibited growth in the face of both genders, while slightly bigger changes in the form of the face were observed in the boys' samples. For girls and boys the most intensive growth was found in the direction of the width and height of the entire face and the nose, especially in the direction of length. These changes took place throughout the whole studied period of growth, yet more intensive growth was evident for girls beginning at age 10 years and for boys from 11 years onward. Shape changes also occurred with age for both genders: the face gradually narrowed, the cheeks flattened and a more retruded position of the forehead...
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Variability and developmental changes of human face between 3 and 15 years: longitudinal and transversal approach
Moštková, Miroslava ; Velemínská, Jana (advisor) ; Zemková, Daniela (referee)
- 1 - Abstract The intent of this thesis is to evaluate the differences in facial morphology of children between 3 and 15 years of age based on 3D facial models and cross-sectional data. Due to improper use of cross-sectional data for studying growth, the next part of the thesis is focused on the comparison of cross-sectional and longitudinal approaches in research. The longitudinal observation of facial developmental changes can be considered as actual growth. The cross-sectional database contains 839 3D facial models (397 boys, 442 girls). Three previously published longitudinal databases were used for comparison. Their age intervals were as follows: 3 to 6 years (12 boys, 14 girls), 6 to 12 years (15 boys, 18 girls), 12 to 15 years (23 boys, 22 girls). Geometric morphometric methods were used to analyse facial models (Coherent Point Drift - Dense Correspondance Analysis, Per Vertex T-Test and Principal Component Analysis). The results were visualized using superimposition colour maps, shell distance significance maps and their interlacing. When annual consecutive age intervals were used for cross-sectional data, we could not observe the fluency of differences in facial morphology between age categories, which we can observe during actual growth. When wider age intervals were used for cross-sectional...
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Development of the oronasal facial region in children aged 7-17 years: longitudinal study
Jungvirtová, Tereza ; Velemínská, Jana (advisor) ; Moslerová, Veronika (referee)
This thesis is based on longitudinal monitoring of developmental changes of the oronasal region in a group of children from 7 to 17 years. Growth and shape changes, variability and sex dimorphism were monitored using 492 3D facial models of 40 boys and 47 girls. These models were obtained by yearly scanning children aged 7 to 12 years and 12 to 17 years. The Vectra 3D optical scanner was used to obtain the models and data were evaluated using classical and geometric morphometry methods (T-test, DCA, Per vertex T-test and Principal component analysis). The results of the analyses were visualized using superprojection color maps of average faces and significance maps that show statistically significant regions of oronasal region changes. During the period under review, the growth of the oronasal region is evident in both girls and boys. The most intense growth occurred in the area of the nasal spine in both sexes, so there was a lengthening of the nose. Overall, the oronasal region extended and expanded to acquire a more convex shape. Growth intensity increased in girls from 10 years and in boys from 11 years. Sexual dimorphism was pronounced up to 11 years, between 12 and 13 the differences were not as pronounced as in the previous age categories, and these changes began to increase again from 14...
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Variability and developmental changes of human face between 3 and 15 years: longitudinal and transversal approach
Moštková, Miroslava ; Velemínská, Jana (advisor) ; Zemková, Daniela (referee)
- 1 - Abstract The intent of this thesis is to evaluate the differences in facial morphology of children between 3 and 15 years of age based on 3D facial models and cross-sectional data. Due to improper use of cross-sectional data for studying growth, the next part of the thesis is focused on the comparison of cross-sectional and longitudinal approaches in research. The longitudinal observation of facial developmental changes can be considered as actual growth. The cross-sectional database contains 839 3D facial models (397 boys, 442 girls). Three previously published longitudinal databases were used for comparison. Their age intervals were as follows: 3 to 6 years (12 boys, 14 girls), 6 to 12 years (15 boys, 18 girls), 12 to 15 years (23 boys, 22 girls). Geometric morphometric methods were used to analyse facial models (Coherent Point Drift - Dense Correspondance Analysis, Per Vertex T-Test and Principal Component Analysis). The results were visualized using superimposition colour maps, shell distance significance maps and their interlacing. When annual consecutive age intervals were used for cross-sectional data, we could not observe the fluency of differences in facial morphology between age categories, which we can observe during actual growth. When wider age intervals were used for cross-sectional...
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