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Influence of cervical spinal cord lesion on cardiovascular fitness
Machač, Stanislav ; Kolář, Pavel (advisor) ; Vilikus, Zdeněk (referee) ; Nováková, Marie (referee)
Traumatic damage to the cervical spinal cord has a dramatic impact on determinants affecting cardiovascular fitness. In tetraplegia, in addition to diminished skeletal muscle function, impaired sympathetic cardiovascular innervation together with a dysfunction of catecholamine release is typically present. Individuals with tetraplegia are at a high risk of long-term inactivity, which increasingly contributes to the development of common civilization diseases. The aim of the current dissertation project is to investigate the cardiovascular fitness in males with cervical spinal cord injury (n=20) as compared to able- bodied males (n=27). Both groups completed exercise testing on an arm-crank ergometer. Arterial blood pressure response to exercise, peak oxygen consumption and peak heart rate were the primary outcome variables. In the first part of the study, a graded maximal arm- crank ergometer test to the subjective exhaustion was performed for the inter-group peak exercise comparison. The peak power dramatically differs between the groups and could be an important confounding factor limiting the evaluation of a physiologic response related to the equivalent physical loading. Therefore, in the second part of the study, individuals of the control group completed a second graded arm-crank ergometer...
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The effect of sauna on the changes of blood pressure
Benko, Michal ; Bunc, Václav (advisor) ; Heller, Jan (referee)
Title: The effect of sauna on the changes of blood pressure Objectives: The aim of this study was the measure of the physiological range (blood pressure, heart rate, blood oxygen saturation) of two selected groups of people within the sauna cycle, assess changes and compare the results of individual probands and groups. Methods: This thesis is conducted as an experimental study. This is a quantitative method, in that will be at first established hypotheses and then evaluated on the basis of the obtained results. The independent variable in this research is the sauna and dependent variables are blood pressure, heart rate and blood oxygen saturation. Results: Blood pressure values were at employee of sauna lower than at other probands, thereby was confirmed hypothesis, but expected significant differences between the measured values of each group were absent. At the same time there was a further confirmation of the hypothesis concerning heart rate, which was increased at all probands. The last confirmed hypothesis related to the blood oxygen saturation and its reduce after the sauna. It could be said that all the defined hypotheses were confirmed. Keywords: sauna, blood pressure, heart rate, blood oxygen saturation, cardiovascular system
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The reflective effect of manipulative therapy on blood pressure.
Martínek, Josef ; Bitnar, Petr (advisor) ; Slabý, Kryštof (referee)
The topic of the thesis is The reflective effect of manipulative therapy on blood pressure. The aim of the thesis is to summarize current knowledge, which talk about the relationship between the ma-nipulative therapy and the changes of blood pressure. One of the purpose of the thesis is to clarify the using of manipulative therapy in the treatment of arterial hypertension. In the thesis another methods of manipulative therapy are discussed to give broad overwiev and to have a posibble to comparison. Powered by TCPDF (www.tcpdf.org)
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Reactions of cardiovascular system to locomat therapy in patients with lesion of the spinal cord
Stráníková, Kateřina ; Radvanský, Jiří (advisor) ; Kříž, Jan (referee)
Introduction - This thesis focuses on the reaction of cardiovascular system to Lokomat therapy in patients with lesion of the spinal cord. It observes reaction of the heart rate and systolic blood pressure and compares with the cardiovascular response to the exercise on an upper body ergometer. Methods - We recruited 25 patients with spinal cord lesion under Th 5 and 4 patients with lesion above Th 5. The blood pressure was measured. The heart rate was measured by by ambulatory blood pressure monitor and an auscultatory method using a mercury manometer and a stethoscope a sporttester. Patients were measured during the Locomat therapy and the exercise on an upper body ergometer during the 6-minute arm test. Results - The parameters of systolic blood pressure and heart rate had a tendency to increase with the peak in 25th minute of the therapy. There was no significant difference between the patients with lesion under or above Th5. The parameters of heart rate were significantly higher on the upper body ergometer than on Lokomat. Conclusion - The Lokomat therapy does have a positive influence to cardiovascular system of patients with complete or incomplete spinal cord injury. When using this approach, the most important benefit is the possibility to activate all parts of body. Keywords: spinal cord injury,...
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The effect of sauna on the changes of blood pressure
Benko, Michal ; Strejcová, Barbora (advisor) ; Bunc, Václav (referee)
Title: The effect of sauna on the changes of blood pressure Objectives: The aim of this study was the measure of the physiological range (blood pressure, heart rate, blood oxygen saturation) of two selected groups of people within the sauna cycle, assess changes and compare the results of individual probands and groups. Methods: This thesis is conducted as an experimental study. This is a quantitative method, in that will be at first established hypotheses and then evaluated on the basis of the obtained results. The independent variable in this research is the sauna and dependent variables are blood pressure, heart rate and blood oxygen saturation. Results: Blood pressure values were at employee of sauna lower than at other probands, thereby was confirmed hypothesis, but expected significant differences between the measured values of each group were absent. At the same time there was a further confirmation of the hypothesis concerning heart rate, which was increased at all probands. The last confirmed hypothesis related to the blood oxygen saturation and its reduce after the sauna. It could be said that all the defined hypotheses were confirmed. Keywords: sauna, blood pressure, heart rate, blood oxygen saturation, cardiovascular system
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The influence of the physical activity on high blood pressure in patients with obesity or metabolic syndrome.
Pazderová, Monika ; Matoulek, Martin (advisor) ; Štulc, Tomáš (referee)
Author's first name and surname: Bc. Monika Pazderová Supervisor of the thesis: MUDr. Martin Matoulek, Ph.D. Thesis title: The influence of the physical activity on high blood pressure in patients with obesity or metabolic syndrome Workplace: 3rd Medical Department, 1st Faculty of Medicine, Charles University and General Teaching Hospital in Prague and Health rehabilitation centre VŠTJ MEDICINA Prague Year of thesis defence: 2012 ABSTRACT Nowadays the metabolic syndrome belongs worldwide to the most widespread diseases. The joint occurrence of diabetes, obesity and hypertension has been known for a long time. Also nowadays many doctors consider obesity a typical risk factor for diabetes or hypertension. Generally it is true: the higher BMI the higher likelihood of hypertension occurrence. Hypertension is a risk factor for atherosclerosis which is a cardiovascular disease. Nowadays the high blood pressure belongs to the most common health disorders of populations in both developing and advanced industrialized countries. The complications of hypertension are an important cause of sickness rate, invalidity and death. The occurrence of high blood pressure increases with age and is also dependent on the gender. The average levels of systolic pressure increase with age. On the other hand, the average levels of...
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Influence of defined olfactory stimuli to selected physiological parameters
Mažárová, Silvia ; Pánek, David (advisor) ; Vláčilová, Ivana (referee)
Title: Influence of defined olfactory stimuli to selected physiological parameters Objectives: Comparing the effect of inhibiting and stimulating scents on the chosen physiological parameters during a 20 minute long inhalation. The thesis is searching for the possible affections to cardiovascular system and to reactibility of the neuromuscular system of the aromatherapy. Methods: 10 individuals participated on the trial, 5 females and 5 male. As the inhibiting scent we chose essential oil of Lavandula angustifolia and as the stimulating scent Rosmarinus officinalis. The observed physiological parameters was heart rate, blood pressure, present emotional state using the Visual Analogue Mood Scale by Stern, results of the Petries' test and standing on two scales test. The chosen application form of the essential oils was inhalation. The observed parameters were recorded before the application of scents, in the 10th and 20th minute of the application and 20 minutes after the end of application. We used the method of comparison. With statistical analysis we compared the results of the mentioned tests and diagnostic methods before and after application each of the odors. Results: We consider that Lavandula angustifolia and Rosmarinus officinalis have statistically significant effect to cardiovascular...
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The role of adrenergic system in genetic hypertension
Loučková, Anna ; Kadlecová, Michaela (advisor) ; Husková, Zuzana (referee)
The adrenergic system plays an important role in the regulation of blood pressure. In the spontaneously hypertensive rat, the most studied model of essential hypertension, many components of the adrenergic system are altered. Changes in expression level of any catecholamine biosynthetic enzymes or any adrenergic receptor subtypes could be one of the causes of hypertension development. In this work, the expression of adrenergic system genes was measured in adrenal gland, renal cortex and renal medulla of the spontaneously hypertensive (SHR), Wistar-Kyoto and Brown Norway rats at the age of thirteen weeks. In adrenal gland of SHR, all four catecholamine biosynthetic enzymes (tyrosine hydroxylase, DOPA decarboxylase, dopamine β-hydroxylase and phenylethanolamine-N- methyltransferase) and almost all subtypes of adrenergic receptors (with the exception of Adra1a and Adra1d) were underexpressed. This generally decreased expression in adrenal gland of SHR suggests that at least a part of regulation of adrenergic system gene expression is common. The mechanism of this downregulation in SHR could be a negative feedback through adrenergic receptors stimulated by high plasma noradrenaline concentration. In the kidney of SHR, there were no differences in the expression of most of adrenergic receptor subtypes with the...
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L-serine induced effects on blood pressure in normotensive and hypertensive rats: the influence of anesthesia
Bencze, Michal ; Zicha, Josef (advisor) ; Husková, Zuzana (referee)
Anesthetics cause profound alterations in respiratory and cardiovascular systems. Our experiments demonstrated that different anesthetics caused different changes in blood pressure regulating components. The role of particular BP regulating systems was disclosed by their selective inhibition - sympathetic nervous system blocked by pentolinium (peripheral ganglionic blockade), renin-angiotensin system by captopril (angiotensin converting enzyme blocker) and nitric oxide production by L-NAME (nitric oxide synthase blocker). Components of blood pressure regulating mechanisms in conscious normotensive Wistar rats and spontaneously hypertensive rats were compared with four different groups of anesthetized rats by pentobarbital, ketamine-xylazine, chloralose-urethane and isoflurane. Each anesthesia caused different hemodynamic changes. If hemodynamic conditions should be similar to conscious rats, the most suitable anesthetic is pentobarbital. L-serine-induced effects represent endothelium-derived hyperpolarizing factor (EDHF)-mediated response, which is a type of endothelium-dependent regulation of vascular tone, independent of nitric oxide and prostacyclin production. Pronounced L-serine effects on blood pressure were shown in NO-deficient type of hypertension. Our study demonstrated its pronounced effects in...
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