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Host manipulation as a helminth strategy increasing the probability of further transmission
Urbanová, Monika ; Horák, Petr (advisor) ; Bulantová, Jana (referee)
The manipulation hypothesis deals with the ability of some parasitic organisms to efficiently change the phenotype of their hosts to facilitate their transmission. The parasite thus gains a selective advantage and, compared to non-manipulating species, is more reproductive. This phenomenon can also be observed in some parasitic helminths. The objects of helminth manipulation are most often invertebrates, who serve as intermediate hosts. In infected animals, we can observe striking morphological changes, abnormal movement reactions, or even suicidal tendencies. The objects of helminth manipulation are most often invertebrates, who serve as intermediate hosts. Manipulation can be divided into direct and indirect, depending on whether the parasite is able to act directly on the nervous tissue of the host. The desired behavioral response can be elicited in other ways, for example, by disrupting the host's metabolism or through complex interactions with the immune system. This thesis focuses mainly on the presentation of various strategies that are most often described in helminth manipulators. Key words: Helminth, host, infection, manipulation, behavioral change, extended phenotype
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Active and Autonomous Approach to Health Care, Seeking an Ideal Insured
Macháček, Vít ; Remr, Jiří (advisor) ; Uherek, Zdeněk (referee)
The author of the thesis formulates theoretical starting points, which draws attention to the problems of the health care system. It emphasizes the role of the individual and describes the mechanism by which it is possible to naturally and freely intervene in the health insurance system. A key role in this mechanism is provided by health insurers, which have the potential to moderate the relationship of the insured with the health system. The health insurer can do so by segmenting their insured and product orientation. The construction of the "ideal insured" should contribute to the this segmentation. The construction is based on the active and autonomous approach of the insured, these qualities are highly valued in the theory presented and it is assumed that this approach is desirable in terms of prevention. The author has created a tool to measure this construct. The tool is in the form of a questionnaire that is systematicaly reduced to include as few items as possible so it can be easily used in practice. Practical usability is the primary goal of creating this instrument to measure "ideal insured".
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