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Detection of the nerve fibres in ophthalmologic images
Urbánek, Dušan ; Harabiš, Vratislav (referee) ; Kolář, Radim (advisor)
This thesis deals with detection of the retinal nerve fiber layer in gray level retinal images taken by fundus camera. The first part describes a physiology of human eye and glaucoma disease. Then, the use of wavelet transform and algorithm of texture analysis applied for texture analysis. Next chapters describe theory of texture analysis named „Gray level run length matrices“ and its application for detection of the nerve fiber layer. Applications of this method are described for three types of retinal tissues and for whole image. The last chapter describes gray levels around optic disc and results obtained from parameters from GLRL matrices.
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Analysis of Retinal Image Data to Support Glaucoma Diagnosis
Odstrčilík, Jan ; Kybic, Jan (referee) ; Matula,, Petr (referee) ; Kolář, Radim (advisor)
Fundus kamera je široce dostupné zobrazovací zařízení, které umožňuje relativně rychlé a nenákladné vyšetření zadního segmentu oka – sítnice. Z těchto důvodů se mnoho výzkumných pracovišť zaměřuje právě na vývoj automatických metod diagnostiky nemocí sítnice s využitím fundus fotografií. Tato dizertační práce analyzuje současný stav vědeckého poznání v oblasti diagnostiky glaukomu s využitím fundus kamery a navrhuje novou metodiku hodnocení vrstvy nervových vláken (VNV) na sítnici pomocí texturní analýzy. Spolu s touto metodikou je navržena metoda segmentace cévního řečiště sítnice, jakožto další hodnotný příspěvek k současnému stavu řešené problematiky. Segmentace cévního řečiště rovněž slouží jako nezbytný krok předcházející analýzu VNV. Vedle toho práce publikuje novou volně dostupnou databázi snímků sítnice se zlatými standardy pro účely hodnocení automatických metod segmentace cévního řečiště.
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Texture analysis of retinal images
Mikauš, Jakub ; Odstrčilík, Jan (referee) ; Gazárek, Jiří (advisor)
The thesis deals with the detection of the nerve fiber layer disruptions in retina scans. The introduction presents an overview of the human eye fysiology and analyses the input image data. The thesis continues with an investigation of two texture analysis methods. While the method of adapted filters does not produce very good results, the method of brightness assessment is shown to work satisfactorily. The final part of the thesis describes the implemented tool for the detection of the nerve fiber layer disruptions.
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Analysis of 3D CT image data aimed at detection and classification of specific tissue structures
Šalplachta, Jakub ; Malínský, Miloš (referee) ; Jan, Jiří (advisor)
This thesis deals with the segmentation and classification of paraspinal muscle and subcutaneous adipose tissue in 3D CT image data in order to use them subsequently as internal calibration phantoms to measure bone mineral density of a vertebrae. Chosen methods were tested and afterwards evaluated in terms of correctness of the classification and total functionality for subsequent BMD value calculation. Algorithms were tested in programming environment Matlab® on created patient database which contains lumbar spines of twelve patients. Following sections of this thesis contain theoretical research of the issue of measuring bone mineral density, segmentation and classification methods and description of practical part of this work.
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Intelligent features classification aimed to support diagnosis of glaucoma
Vykoupil, Pavel ; Čmiel, Vratislav (referee) ; Odstrčilík, Jan (advisor)
This bachelor thesis deals with inteligent features classification aimed to support diagnosis of glaucoma. First part focuses on eye anatomy and disease called glaucoma. In next part is briefly described texture analysis and how do we get attributes for classification. In last part it is dealt with attribute classification with the aid of neural networks and algorithm HoKashyap and AdaBoost. This thesis is therefore focused on comparing effectivity of these classifiers on the field of optical diagnostics which was managed successfully.
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Texture Analysis of Ophthalmologic Images
Kaňka, Jan ; Odstrčilík, Jan (referee) ; Jan, Jiří (advisor)
This thesis is concerned with creating of software for textural analysis of retinal images by statistic method called co-occurrence matrices as possible alternative method to detection of lesion of retina by the glaucoma diseases. The Glaucoma diseases without well-timed diagnostics and consequential treatment leads to blindness. The retinal images captured by fundus camera are common, easily processable and modern devices are able to make images of 10 Mpix resolution and bigger, what specifies outputs of analytic software. Method of co-occurrence analysis is simple and effective statistic. But computing demandingness, showing up with growing objective quality, comming up as disadvantage.
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Texture analysis of retinal images oriented towards detection of neronal fibre layer
Gazárek, Jiří ; Jiřík, Radovan (referee) ; Jan, Jiří (advisor)
The thesis is focused on detection of local disappearance of the neural layer on retina in fundus-camera images. The first chapter describes the human eye physiology, the glaucoma disease and the analyzed data. The second chapter compares four different approaches that should enable automatic detection of a possible damage to the retinal neural layer. These four approaches have been tested and evaluated; three of them showed an acceptable correlation with the medical expert conclusions – the directional spectral approach, the edge based approach and the difference local brightness. The last approch via local co-occurrence matrices has not turned out to be informative with the respect to the issue concerned. Then a program for the automatic detection of the nerve fibre layer loss areas has been designed, realized and evaluated. This task is solved in the last chapter. A relatively good agreement between the medical expert conclusions and the conclusions detected automatically by this program has been reached.
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Extraction of texture features aimed to detect glaucoma defects
Daněk, Daniel ; Kolář, Radim (referee) ; Odstrčilík, Jan (advisor)
The thesis deals with an automatic method of texture analysis using Markov random fields texture modeling. The main aim of this work is to find out relevant textural features, which can be used for appropriate classification of the degree of retinal nerve fiber layer loss. The model of Markovian statistic uses a circular symmetric neighborhood structure and a least square error estimation of the model's parameter. Obtained textural features were quantitatively evaluated using correlation analysis. The results show, that there is a significant correlation between proposed textural features and RNFL thickness measured by OCT. Thus, the features can potentially serve for glaucoma diagnosis.
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Analysis of Ophthalmological Images Aimed to Diagnosis of Glaucoma
Vodáková, Martina ; Kolář, Radim (referee) ; Odstrčilík, Jan (advisor)
Bachelor thesis is focused on fundamental texture analysis of high-resolution fundus images aimed to subjectively and quantitatively describe properties of texture formed by the retinal nerve fiber layer. An area of interest was predefined in the form of ten sectors on each fundus image. The correlation between results of subjective and quantitative evaluation of the texture was monitored in each sector. The results show that proposed fundamental texture features are closely related to the subjective textural properties obtained from visual appearance of the retinal nerve fiber layer. The last step compares results from fundamental texture analysis with quantitative measurement of the retinal nerve fiber layer thickness provided by Optical Coherence Tomography.
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Analysis of retinal nerve fiber layer in fundus images utilizing local binary patterns
Doležal, Petr ; Harabiš, Vratislav (referee) ; Odstrčilík, Jan (advisor)
This work describes LBP (Local Binary Pattern) method in its various forms as a tool for distinguishing images with and without texture. The first part of the essay looks into the retinal nerve fiber layer, loss of the nerve fiber and especially into possibilities of retinal images with help of the fundus camera and into properties of this way received data. Second part of the essay describes and explains the LBP method which uses local binary operators for description of texture by help of histograms. From this way brought force of histograms is possible to gain a complex of features. Due to different classification approaches can then determine if new samples were selected from an image loss of retinal nerve fiber layer (RNFL). This solves the next part of the essay. And then is evaluated the correlation of features of LBP histograms of these images with the thickness of the RNFL in the same place. The methods described in this essay have been tested on a set of images in Matlab program and received results show, that the method can be useful for the diagnosis of glaucoma diseases.
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