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Effect of acute sleep deprivation in different light conditions on the quality of recovery sleep
Zeithamlová, Barbora ; Kopřivová, Jana (advisor) ; Vlček, Kamil (referee)
Sleep is regulated by homeostatic and circadian processes. The circadian process is controlled by the internal biological clock, which is regularly synchronised with the external world by so-called zeitgebers. The most important zeitgeber for humans is light, therefore incorrect timing of light signals can lead to desynchronisation of the clock and sleep disruption; however, this depends on the intensity and spectral characteristics of the light. Dimmed red light is unlikely to significantly interfere with sleep regulation, but white light with a higher intensity could. White light is typically used when people stay awake during the night and experience acute total sleep deprivation. This could potentially interfere with the compensatory mechanisms occurring during subsequent recovery sleep. We therefore decided to test whether and how different lighting conditions during sleep deprivation can affect the structure of recovery sleep. We had 12 healthy uniform volunteers undergo two acute total sleep deprivations; one under normal white light, the other under dim red light. Using polysomnography, we measured the sleep parameters of both recovery sleeps and compared them. It turned out that sleep that occurred after the sleep deprivation in constant dim light conditions was less fragmented, had...
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The effect of sleep on muscle hypertrophy
Toušková, Barbora ; Skálová, Kateřina (advisor) ; Kolář, David (referee)
Sleep represents one of the fundamental aspects of human life and health, influencing many physiological functions including muscle hypertrophy. Sleep is regulated by various external and internal stimuli, such as the circadian rhythm, body temperature, gene expression, and the synthesis of hormones and neurotransmitters such as melatonin and adenosine. Muscle hypertrophy is a complex process of enlarging muscle fibers, which is associated with numerous metabolic processes and signaling pathways, including the IGF-1-PI3K-Akt- mTOR axis, and is regulated by hormones such as testosterone, GH, myostatin, and activin. Most of these hypertrophic factors are closely linked to quality and sufficient duration of sleep. Sleep deprivation negatively affects almost all processes involved in muscle hypertrophy and, in the long term, leads to muscle loss instead. Key words: Sleep, circadian rhythm, melatonin, muscle hypertrophy, Akt, mTOR, sleep deprivation
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Circadian regulation of body temperature
Knobloch, František ; Bendová, Zdeňka (advisor) ; Horníková, Daniela (referee)
This thesis addresses the topic of circadian control of body temperature, a key aspect for understanding the temporal regulation of the body and its influence on physiological processes. Temperature is a strong signal that is under the strict control of the thermoregulatory system, which very effectively prevents major fluctuations even under non-standard conditions. Although the daily rhythm in body temperature oscillates within a very narrow range, it is an important information for all the cells of our body, which contributes to their coordinated functioning. This thesis synthesizes the available knowledge on how the circadian system creates this rhythm and how temperature and factors that influence body temperature may in turn enter into the temporal regulation of our body. The aim is to contribute to a better understanding of the dynamics between the circadian system and thermoregulation, and to highlight the many bidirectional connections that may overlap with countless other physiological processes.
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The effect of the circadian rhythm on the work of a paramedic
ŠEDIVÝ, Martin
The topic of the bachelor's thesis is "The effect of the circadian rhythm on the work of a paramedic". Most rescuers may not even realize the great sacrifice they make by performing this demanding profession. This is a very respectable job, which is burdened with a huge amount of stress and a demanding work schedule. The combination of these two unfavorable factors may have a negative impact on the health of rescuers over a longer period of time. The theoretical part deals with the explanation of the term circadian rhythm, sleep and its structure, nutrition, physical activities, blue light, caffeine, health complications that are the result of a disturbed circadian rhythm and the effect of circadian rhythmicity on work efficiency. The research part was implemented using semi-structured interviews, and 12 informants who are employed at the South Bohemian Region Medical Rescue Service in the position of paramedic were included in the research investigation. Each informant was asked the same questions, which were then evaluated using the coding technique and were divided into several categories and subcategories. The main topics for responding the objective of the work were health complications of shift work, adaptation to shift work, principles of proper nutrition and sleeping habits. Research has shown that the circadian rhythm affects the work of a paramedic, but it is very individual and affects each paramedic in a different way. Alternating irregular shifts are difficult to get used to, and working at night is not ideal from a physiological point of view. Most of the rescuers confirmed to us that they had a lower work performance and a longer reaction time during the night hours. Furthermore, night shifts have a negative effect on the health of workers, and health complications may occur years later, which may not allow rescuers to continue to perform their work as well as before.
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Zlín FCK Technology
Morávek, Jakub ; Kudla, David (referee) ; Štěpán, Marek (advisor)
The diploma thesis deals with the design of a residential building in the area of Malenovice near Zlín, where a new residential complex is to be built on the land of the current Malenovice sawmill, situated in close proximity to a four-lane road. The concept of this proposal is based on a detailed examination of human cycles and their impact on people in everyday life in relation to architecture. From the life cycle through the annual cycle and especially the daily cycle, professionally referred to as the circadian rhythm. The building, with its idea concept, orientation to the cardinal points, zoning of the apartment and also the shape solution, responds to the needs of man in terms of light comfort and at the same time addresses the greatest efficiency of the technologies used precisely in relation to light comfort, the form solution also creates conditions at the terrace level for the meeting of a wide range of inhabitants of the house - creating diversity. It reduces the need to illuminate the space during the day with artificial lighting, and after dark it addresses artificial lighting with respect to human health, thus also reducing energy consumption.
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SLEEPING OUTDOORS
Bendák, Jan ; Tomalík, Michael (referee) ; Tobola, Ondřej (advisor)
The work deals with the influences acting on humans when staying in the outdoor environment and their effects on our daily rhythm. It focuses closely on the ritual of sleeping outside. It strives for a natural understanding of the laws of nature through exposure to the influences that affect us open air on a daily basis. Seasons, weather, light and other factors are determining elements for the work. The result of understanding and combining these principles are outdoor structures designed to accomodate groups or individuals overnight. The objects should serve as a platform for creating a community that will further develop these principles autonomously. The aim is to present the positives of sleeping outside, delimit against the trend of unsustainable growth and to provide an example of how to deal with this tendency through the perception of nature.
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Lighting with Tunable Spectral Distribution and Its Influence on Human Physiological Functions
Hanák, Petr ; Bendová,, Zdeňka (referee) ; Baxant, Petr (advisor)
In this diplomat theses are considered the effects of light on human beings, especially on physical performance. The goal of this work was to design a suitable method for evaluation of the effects of light on physical performance. Furthermore, to verify designed methods in laboratory environment and the assessment of collected data. After creating this method several people were tested under different light conditions and collected date evaluated. The results are suggesting that high intensity lighting with low wave lengths leads to an increase of physiological activity in organism and therefore to a potential decreasing physical performance.
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Illumination with respect to biological functions
Němec, Jiří ; Štěpánek, Jaroslav (referee) ; Baxant, Petr (advisor)
The paper summarizes the basic light-technical parameters, the principles of visual and non-visual photoreceptions and the effects of light on the organism. Several chapters focus on the mechanism by which light affects hormone levels and the circadian rhytm of the organism. In relation to the lighting system, the impact of electromagnetic radiation, associated with the controls, on the body is also considered. Briefly described are systems based on smart LED light sources or smart switches. The result of the thesis is to choose the solution that best suits the requirements of the contracting authority.
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The effect of the blue light on the human body
Dvořák, Petr ; Krbal, Michal (referee) ; Štěpánek, Jaroslav (advisor)
This thesis explains the term „blue light“. It deals with the sources of blue light and the effects of this type of electromagnetic radiance on human body. The focus is concentrate especially on problems, which are evocated of blue light. The biggest danger is the desynchronization of circadian rhythm and photochemical damage of retina – photoretinitis („blue light hazard“). The basic principles of biological processes and the visual system are described here. These processes are controlled by properties of incident light onto the retina of eye. The basic information about artificial sources of blue light commonly used in households and in industry are mentioned in the second half of work. These light sources were measured and elaborated. The electromagnetic spectrums of sources are portrayed and there is a comparison of sources due circadian effect too.
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Vliv vybraných faktorů na spánek
Brožová, Kateřina
The bachelor thesis deals with the factors that can influence human sleep. The thesis discusses the effects of stress, weather, caffeine, room temperature and lighting on human sleep. Part of the thesis is devoted to lighting - its evolution, distribution and its proper use in interior design. The thesis also discusses sleep, its importance, stages and possible sleep disorders, which can be caused, among other things, by light disrupting the circadian rhythm. Another section of this bachelor thesis deals with the effect of artificial and natural light on sleep. It describes both its negative and positive effects on the organism. The design of bed furniture with integrated lighting is based on these findings. The work is divided into two parts - theoretical and practical. The theoretical one focuses on the influence of selected factors on sleep, while the practical one deals with the actual design of bed furniture with integrated lighting and the measurement of sleep quality.
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