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Protein hot spots prediction
Kašpárek, Jan ; Tkacz, Ewaryst (referee) ; Maděránková, Denisa (advisor)
Knowledge of protein hot spots and the ability to successfully predict them while using only primary protein structure has been a worldwide scientific goal for several decades. This thesis describes the importance of hot spots and sums up advances achieved in this field of study so far. Besides that we introduce hot spot prediction algorithm using only a primary protein structure, based primarily on signal processing techniques. To convert protein sequence to numerical signal we use the EIIP attribute, while further processing is carried out via means of S-transform. The algorithm achieves sensitivity of more than 60 %, positive predictive value exceeds 50 % and the main advantage over competitive algorithms is its simplicity and low computational requirements.
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Design of clamping device for CNC milling machine
Kašpárek, Jan ; Dočkal, Kryštof (referee) ; Svoboda, Petr (advisor)
The bachelor thesis deals with clamping fixtures problematics for parts with difficult shapes. It aims to design an effective way of clamping of a part machined on CNC machining centre. The output is an adjustment of commercially available clamping system to suit requirements of assignment. The efficiency of the manufacturing process is determined by machining time calculations that showed that series will be finished in required time. Besides that, the thesis provides an overview in various fields, such as used materials in automotive industry, used machining centres in automotive industry and also the overview in principles of clamping.
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Business Plan
Vinkler, Lukáš ; Kašpárek, Jan (referee) ; Šimberová, Iveta (advisor)
This Bachelor´s thesis is divided into three main parts. Firstly, theoretical one describes individual parts of a business plan. Then, this thesis compiles chosen analysis of the ski school and rental ARON Sport based on knowledge of the first part. These analysis serve as a basic for suggestions that get better a current adverse situation of the ski school.
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Compression of ECG signals
Kašpárek, Jan ; Kozumplík, Jiří (referee) ; Hrubeš, Jan (advisor)
This thesis contains general description of several basic compression algorithms used either for lossy and lossless compression. These algorithms are runlength encoding, Lempel-Ziv, Huffman encoding, Move-to-Front, wavelet transform and Burrows-Wheeler transform. Aim of this thesis is creation of ECG compression algorithm with implementation of runlength encoding and BWT. Another technique used in algorithm is wavelet transform. The algorithm is written in programming environment MATLAB.
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The Tools and Equipment for a Bending of Tubes
Kašpárek, Jan ; Štroner, Marek (referee) ; Peterková, Eva (advisor)
The bachelor thesis is aimed to make a general overview of used tools and equipment for a bending of tubes. On the basis of literary evidence the list of basic methods used in bending tubes was created. By conducting a survey in bending tubes producers manufacturing programs, various principles of bending tubes were described, which are supplemented with picture documentation. To each method there were mentioned some of the OEMs. Accompanying pictures describe the construction of individual machines and used tools and equipment.
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Design of clamping device for CNC milling machine
Kašpárek, Jan ; Dočkal, Kryštof (referee) ; Svoboda, Petr (advisor)
The bachelor thesis deals with clamping fixtures problematics for parts with difficult shapes. It aims to design an effective way of clamping of a part machined on CNC machining centre. The output is an adjustment of commercially available clamping system to suit requirements of assignment. The efficiency of the manufacturing process is determined by machining time calculations that showed that series will be finished in required time. Besides that, the thesis provides an overview in various fields, such as used materials in automotive industry, used machining centres in automotive industry and also the overview in principles of clamping.
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