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Filter interesting rules in EasyMiner system
Duben, Přemysl Václav ; Vojíř, Stanislav (advisor) ; Zeman, Václav (referee)
Postprocessing is like data preparation one of the most challenging tasks in data mining that users must deal with. It is desirable to simplify it so that the path to results is as fast and efficient as possible. The extension of the EasyMiner research project to filter the association rules by similarity to the knowledge-based rules, should be helped in this respect, which is the subject of this diploma thesis. The objectives were accomplished by a detailed analysis of the default state of EasyMiner in conjunction with a thoroughly thought-out implementation proposal without increasing the demands on the server or user of the application. An analysis of general practices and the author's deep knowledge of Internet application issues served to do this. The future deployment of this extension to the EasyMiner infrastructure will benefit from a clearer and more efficient work with the Knowledge base part, where it will no longer be necessary to evaluate the interest in the same or similar rules and the user will be able to focus directly on the quality of the results. This thesis is divided into chapters as a detailed description of how a similar problem can be approached in any other project that works with a certain form of knowledge base. Initial input analysis with access search for comparison of the various elements passes through a description of the default application state to a specific solution design. This should be a guideline for the implementation itself and for the testing of the proposed and implemented procedures.
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Graph-based molecular representation and its utilization in virtual screening
Šťastná, Aneta ; Hoksza, David (advisor) ; Kopecký, Michal (referee)
Graphs are natural way of representing molecules. However, graph representations and algorithms are not being used for finding similarity of molecules in virtual screening. In this work we test the graph-based methods in ligand-based virtual screening. The similarity of molecular graphs is determined by maximum common subgraph and graph edit distance. We use implementations fmcs from chemoinformatic library RDKit for maximum common subgraph and GraphMatchingToolkit from K.Riesen to determine graph edit distance. We have found suitable combinations of parameters for aplication in ligand-based virtual screening. The results suggest that performance of graph based methods is comparable to the state-of-the-art methods.
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God's Image in Gregory of Nyssa
Marunová, Magdalena ; Karfík, Filip (advisor) ; Bartoň, Josef (referee) ; Dus, Jan (referee)
The aim of this work is to introduce Gregory of Nyssa's doctrine of man as the image of God, based especially on his work Περ κατασκευ ς νθρώπουὶ ῆ ἀ (De hominis opificio). In his work Gregory created quite a systematic anthropological treatise based on Stoic sources, Biblical interpretations inspired by Philo of Alexandria and Origen, as well as on ancient medicine. In contrast to the ancient philosophical school views concerning human being, Gregory refuses the parallel of man as a small world and says that the dignity of man consists not in being similar to the created world, but to the Creator. There are many attributes that constitute human similarity to God, but especially due to the incomprehensibility man is the image of God. The incomprehensibility consists in human mind (νο ςῦ ) in which the human likeness to God can most apparently be recognized. It cannot be placed anywhere in the body and the connection between mind and body is, according to Gregory, unspeakable: the mind does not reside in any particular part of the body, but yet it acts in and is influenced by the whole body. The image of God is the whole mankind, from the first up to the last created human being. When the planned number of souls is completed, the time and everything that happens in time will come to an end. In the...
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Vícenásobná podobnost RNA struktur
Szépe, Peter ; Hoksza, David (advisor) ; Novák, Jiří (referee)
The work is based on the algorithm SETTER (Secondary Structure Tertiary Structure-based Similarity Algorithm), which is designed to compare the 3D structures of RNA. SETTER in the original version can only compare pairs of RNA, however many applications require real similarity comparison between a set of RNA structures. The main idea used in MultiSETTER is a well-known approach used for multiple sequence alignment, which is based on the Neigbour-Joining method - a method for calculation of the taxonomic tree from distances between taxa - and on pairwise alignment. At each step the closest pair is aligned according to the taxonomic tree. To achieve good results, it was necessary to invent a method that creates a fictive average RNA structure by merging two RNAs that shares the structural characteristics of both RNA.
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Visual experince as example and pattern in relation to the expansion and influence into human life
Nohejl, Jiří ; Wittlich, Filip (referee)
The main theme of this dissertation is to define an image as a visual experience. The human interaction is described by the author himself as a perception of the image, which serves as an information unit that could be presented as a possibility, example and pattern for the individual. There is an emphasis on the process of perception itself and on the way of interaction of an individual emphasizing the context of social learning and imitation in this text. The analysis of the principles of this interaction leading into introduction of the partial interactive models covering these processes is formed by the essential plane. The structure of the thesis is divided into ten main chapters in which the author tries to introduce a category of perception, a definition of the image and imitation as a tool of cultural transmission, presentation of the units of this transmission, the process of the interaction itself and analogous example of the fundamental role that a person in this interaction holds. There are also three analogies of these roles, which refer to the anthropological universal interaction describing the man as a gatherer and hunter. Their main purpose is to illustrate the form of a human experience better. Finally, there are reflections on the topic above. The possibilities and results, which...
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Protein Structure Similarity Using Genetic Programming
Šiagi, Miroslav ; Hoksza, David (advisor) ; Mráz, František (referee)
The thesis deals with the protein structure similarity problem which is an important aspect of bioinformatics. Due to exponential growth of protein structures in databases, the development of more effective methods is required. Principles of evolutionary computation offer a way to solve the similarity problem. We focus on one of the evolutionary paradigms - genetic programming. The main advantage of genetic programming is a tree representation. We propose new method called ProSSiGen using genetic programming. ProSSiGen is evaluated by automatic protein classification. Obtained results signify that the efficiency of our method is insufficient. Regardless of the inefficiency, there are many reasons to continue to research. One of the reasons is the capability of genetic programming.
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The Mimesis - Imitatio in the autentic Letters of Paul
Mátiková, Anna ; Brož, Jaroslav (advisor) ; Scarano, Angelo (referee)
Mimesis - Imitatio in the Authentic Letters of the Apostle Paul The first part of the thesis provides the reader with a concise overview of different semantic levels of the term mimesis as found in the ancient literature written in the Greek language. Furthermore, the author focuses her attention on the use of the concept of mimesis in the Old Testament, and the New Testament writings other than Paul's authentic letters. Such a survey prepares the ground for a detailed study of the concept of mimesis in the authentic letters written by the Apostle Paul. The idea of mimesis is present in Paul's authentic letters in five explicit passages (1 Tess 1:6-7; 1 Tess 2:14; 1 Cor 4:16; 1 Cor 11:1 a Phil 3:17). Each of the passages is studied within the whole context of the respective letter, written for a group living its own particular situation. The thesis compares different exegetical solutions from several researchers. Some of the researchers understand Paul's appeal to imitation as a call to be obedient to his teaching. Other experts are more inclined to understand this imitation as an authentic representation of the Cross in the life of Jesus' followers. The thesis tries to prove that the mystery of Christ's kenosis, expressed in a very significant way in the Christological hymn contained in the Letter to the...
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Conceptualization of mores in 17 th Century French Tragedy
Šuman, Záviš ; Pohorský, Aleš (advisor) ; Pelán, Jiří (referee) ; Kyloušek, Petr (referee)
214 Abstract Conceptualization of Mores in Seventeenth-Century French Tragedy This thesis is devoted to the study of interpretations of how tragic characters should be portrayed ("mores", "ethos", "mœurs") in French seventeenth-century theories on Tragedy. The theoretical writings of Jean Chapelain, La Mesnardière, Pierre Corneille, d'Aubignac, René Le Bossu, Rapin, Saint-Évremond, Jean Racine and André Dacier are examined in detail. Their findings are compared with the Latin and Italian commentaries on how the Aristotelian notion "character" ("éthé", "éthos") ought to be perceived and understood and what its impact is on dramatic action. The main focus is paid to the detailed analysis of very divergent and often incompatible interpretations of the four Aristotelian conditions outlined briefly in Chapter XV of Poetics and on how the French theorists and dramatists responded to Aristotle's requirements. The first condition requires dramatic character to be "good of its kind" ("chrestos", "ethos" "chreston", "ethe chresta"). The detailed study of contemporary criticism draws us to a conclusion that there are schematically two approaches on how the French theorists conceptualized this very elusive criterion. Whereas Chapelain in his Préface à l'Adone explicitely rejects the moral meaning of "chrestos" and thus...
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Similarity of Serbian and Slovak Language Concerning Substantives
Stojanovičová, Zorica ; Vlainić, Sandra (advisor) ; Jirásek, Karel (referee)
(English): In this bachelor thesis we were trying to compare Serbian and Slovak language in terms of vocabulary according to substantives. Due to extensiveness of the grammatical category of nouns we decided to define our thesis only on family and kinship terminology. In the process of comparing we were using translation and explanatory dictionaries as well as etymological dictionary which was the major indicator whether or not have these two languages the same origin. It turned out that the roots of both Indo-European languages date back to Proto-Slavic languages. While many of the old Serbian kinship names preserved until today, in Slovak we can observe the gradual disappearance. The reasons why they died out are a new way of life, moving from the place of the former residence what is resulting in limited meeting with friends and relatives. The thesis is divided into two parts. In the first part we write about the general terms relating to the family and relatives. The second part already deals with kinship terminology which we categorized into consanguinity (blood kinship), affinity and spiritual kinship.
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Sound records comparison using timbre features
Miklánek, Štěpán ; Schimmel, Jiří (referee) ; Kiska, Tomáš (advisor)
This thesis deals with research of musical features, which are describing music recordings relating to timbre. First chapter deals with historical development and modern approach in a discipline called Music Information Retrieval (MIR), further there is a description of music processing from the perspective of music theory and digital signal processing. Then followed by a description of signal pre-processing. This part is very important when retrieving features from music recordings. In chapter concerned about retrieving features there are summarized all common features used when retrieving information from musical recordings with main concern to timbral features. A database of music recordings and a feature retrieving system is introduced. The last chapter deals with individual analysis of timbral features.
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