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Influence of contraceptives and hormonal substitution therapy on the receptors of sex steroid hormones
Krasulová, Hana ; Tošner, Jindřich (referee) ; Hochmann, Jiří (advisor)
The thesis deals with questions about levels of estrogen and progesteron receptors (ER and PR) in normal breast tissue and in tumorous tissue and explains their changes. The aim of our effort was to find the publications which deal with possibilities of false positivity or negativity in a breast cancer and clarify the time period after which we can expect relevant results of the receptor levels after contraception therapy or hormonal substitution therapy and which concentration of hormones we can expect in serum. First we listed contraception therapy and hormonal therapy. We focused on physiological concentrations of estradiol and progesterone in serum and their potential affection by contraception and hormonal substitution therapy. We found that most of contraceptives contain now such dose of ethinylestradiol to reach such concentration in the serum which are nearly physiological. In postmenopauzal women the estradiol levels decreases in comparison with premenopausal women. The doses of ethinylestradiol during substitution therapy are essentially higher than during contraception therapy. Subsequently we searched for the releationship between levels of ER and PR and their potential affection by contraception or hormonal substituonal therapy. As the Czech literature does not include this questions -...
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Functional and physical fitness of paraplegics
Pivoňková, Jana ; Potměšil, Jaroslav (referee) ; Čichoň, Rostislav (advisor)
In the begining of the theoretic part of the thesis I briefly describe problems of the Spinal cord lesion. In the main part I concentrate on terms definition of the physical and health-related fitness by various authors, fitness testing, then significance physical activity of handicaped people and complications related to physical fitness of paraplegics. In the practical section of this pilot study was aplicated the questionnaire and battery testing, which we have originally created. Respondent fills the questionnaire on his own and the paraplegic's practical skills are evaluated. The battery testing is focuesd on practical measurement of single components of health-related fitness and it is provided by terapeut. Fifteen parplegics participated in the research (14 men, 1 woman). From created graphs of individual questions we were examinating diversions of respondents from average value, individual respondents with each other and we were searching relation with several parameters. We were focusing on practicableness of terrain measurement and we were interested in reactions of paraplegics on the course of the testing, because it was a pilot study. Key words: Transverse Spinal Cord Lesion, Paraplegia, Physical Fitness, Health-Related Fitness, Physical Activity, Battery testing, Questionnaire.
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Possibilities of using swimming pools in Prague for people the reduced physical ability
Chaloupková, Eva ; Břečková, Gabriela (referee) ; Čechovská, Irena (advisor)
Title: Possibilities of using swimming pools in Prague for people the reduced physical ability. Objectives: The goal was to find information and mapping the most indoor public swimming pools in the capital city of Prague. Further mapping of the accessibility or inaccessibility for people with limited movement capabilities. Questionnaire survey based on the assumption that respondents are interested in maintaining your current physical fitness into old age through physical activities. Methods: Traffic information and location indoor swimming pools we have gained through search engines: www.seznam.cz, www.google.com. We searched under the slogan of public swimming pools in Prague. A personal visit and evaluation, we chose swimming pools, which are based on information received, they knew that they meet the requirements of Decree No. 174/1994 Coll. č.369/2001 and Sb, which provides general technical requirements ensuring the use of buildings by persons with reduced mobility (www.tzb-info.cz/t.py). For reasons of personal visits to swimming pools author of this thesis, which is reliant on the movement of a mechanical wheelchair. The remaining pools that do not meet the requirements of Decree No. 174/1994 Coll. č.369/2001 and no, we conserve through a telephone conversation with the operating swimming...
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Expected height of binary search trees
Langhammer, Martin ; Koubková, Alena (advisor) ; Koubek, Václav (referee)
In this thesis we study the expected height and some other qualities of the binary serach trees. We make the inquiry about the expected height by skewed trees and by the two probably best-known and most widely used variations of the balanced trees, it means the AVL and the red-black trees. In addition to the value of the expected height of the trees we found out the scatter of the tree heights and some other statistics. In this thesis we attach to experimental solution of the problems. We also write down all the theoretical results that were known to us. We focus especially on comparing the measured values with the theoretically counted results. We try to acquire as exact assessment as possible in the case of unexisting theoretical results. Besides we compare the di erences between the various trees. We measured speeds of the tree's generation only marginally. We also inquire the dependence on di erent kinds of enter data within the experiments, such as the sorted data or generated data from various sorts of division. We use the standard statistic methods for the interpretation of the results, especially the method of linear regression.
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Data mining from incoming e-mail messages
Šebesta, Jan ; Žemlička, Michal (advisor) ; Hnětynka, Petr (referee)
In the present work we study possibilities of automatic sorting of incoming email communication. Our primary goal is to distinguish information about oncoming workshops and conferences, job off ers and published books. We are trying to develop tool to mine the information from data from professional mailing lists. Off ers in the mailing lists come in html, rtf or plain text format, but the information in it is written in common spoken language. We are developing the system so it will use text mining methods to extract the information and save it structured form. Than we will be able to work with it. We are examining the handling of the mails by user and apply the knowledge in the development. We solve the problems with obtaining of the messages, distinguishing language and encoding and estimating the type of message. After recognition of the bearing information we are able to mine data. In the end we save the mined information to the database, which allows us to display it in well{arranged way, sort and search according to the user needs.
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Mucocutaneous candidiasis and women's sexual hormones
Košťálová, Marie ; Tošner, Jindřich (advisor) ; Kudela, Milan (referee) ; Mencl, Karel (referee)
The aim of this work was to study relationship between mucocutaneous candidiasis (MCC) and women's sexual hormones. This problem is usually solved by dermatologists, gynaecologists and mycologists separately. Our approach is original, because it is primarily based on skin and/or cutaneous appendagies affection and searches for possible coincidence or other relation in vulvovaginal region. We examined 81 women in our study and divided them into two groups according to hormone-level investigation (women in fertile and perimenopausal period, women in postmenopausal period). We also developed "Candida" questionnaire for further anamnestic data correlation. The relationship between MCC and women's sexual hormones was studied both, in vivo and in vitro. We found C. albicans in vagina in both studied groups most frequently at the time of cutaneous candidiasis. In postmenopausal period the incidence of vaginal C. albicans was significantly lower (significantly lower levels of E2, PG). The cultivation identity between skin and vulvovaginal region was more frequent in fertile and perimenopausal period than in postmenopausal one, too. Predominantely concerned C. albicans again, the conformity was considerable in women with established ovulation (significantly higher levels of PG). In presence of C. albicans in...
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Adaptability in XML-to-Relational Mapping Strategies
Kulič, Luboš ; Nečaský, Martin (referee) ; Holubová, Irena (advisor)
One of the ways how to manage XML documents is to exploit tools and functions o ered by (object-)relational database systems. The key aim of such techniques is to nd the optimal mapping strategy, i.e. the way the XML data are stored into relations. Currently the most efficient approaches, so-called adaptive methods search a space of possible mappings and choose the one which suits the given sample data and query workload the most. In the thesis we exploit a general heuristic method called Ant Colony Optimization (ACO) to solve the XML-to-Relational mapping problem. We also adapt the algorithm so it can be used on a dynamic variant of the problem. The algorithms are evaluated in a set of experiments with a conclusion that the ACO-based algorithms are suitable for the problem and can be even used as a basis of a dynamic mapping mechanism.
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Invenio within the NRGL: Version 1.0 and More News
Slouková, Jana
Both digital repositories maintained by NTK (NRGL and IDR) are powered by the open source software Invenio. Its great flexibility allows us its continuous development and adaptation to our needs. This year we added several features that make it easier to work with the repositories - for example, we improved the search, presentation of records, and added export to various citation managers. Following the release of new version of Invenio, we also created a new freely available installation script, that facilitates the installation and basic configuration of the system to those interested in creating their own repository.
Fulltext: idr-508_4 -  PDF
Slides: idr-508_2 - PDF; idr-508_3 - PDF
Video: idr-508_1 -  MP4
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Dynamic Constraint Satisfaction Problems
Surynek, Pavel ; Rudová, Hana (referee)
Constraint satisfaction problems (CSPs) are a type of combinatorial (optimization) problems that invite much interest in many practical applications. CSP is defined by a set of variables, to which values must be assigned, and a set of constraints that restrict these assignments. Since many problems of practical interest require a dynamic environment, the model of CSP was extended to a dynamic CSP (DCSP), in which the set of variables and/or constraints can be modified during the constraint resolution process. To simplify the constraint satisfaction problem for search algorithms, consistency (filtering) techniques like arc-consistency are usually applied. In this thesis, we study the problem of maintaining arc-consistency in DCSPs. We propose several new dynamic arc-consistency algorithms that yield a better compromise between time and space in comparison to similar existing algorithms like DNAC-4, DNAC-6 and AC|DC. The highlight of the work is a new algorithm that outperforms so far fastest algorithm for maintaining arc consistency in dynamic problems DNAC-6. In order to do performance experiments we have developed a library SPlan written in C++. This library solves DCSPs and the new algorithms as like as the comparable existing ones are implemented as a part of the library. Experimental results on randomly...
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Artificial Intelligence for the Bang! Game
Daniláková, Monika ; Pilát, Martin (advisor) ; Děchtěrenko, Filip (referee)
This work explores artificial intelligence (AI) algorithms for the game Bang!, a Wild West-themed card game created by Italian game designer Emiliano Sciarra. The aim of this work was to design three different AIs for this game and to compare them theoretically and experimentally. First, we analyzed game Bang! with regards to game theory, and researched some of the AI algorithms used in similar games. We then designed three different AIs algorithms and compared their advantages and disadvantages. These three AIs included an AI based on the Monte Carlo Tree Search algorithm, a genetic AI and a hybrid AI using elements of both previous AIs. We also implemented the game itself and the AIs in C#. The implementation makes it easy to add more AIs or client applications in the future, and also to compare and train the AIs. Finally, we experimentally compared the implemented AIs. The genetic AI performed the best, while Monte Carlo Tree Search AI and the hybrid AI were less suitable for this game. Powered by TCPDF (www.tcpdf.org)
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