|
The Chicago School of Economy Thought
Holčáková, Tereza ; Holman, Robert (advisor) ; Mičúch, Marek (referee)
The work inquires into one of the most famous schools of economic thougth, (which had been) founded in the second half of the 20th century. Liberal attitude and conservative wiews excercised by its members strongly oposes keynesianism and its politics of state influence on economics. Chicago school represents powerful ideological outlook, importance of which is expressed by a particular number of Nobel awards, earned by its representatives. This school has had a great impact on economic policy of many countries. Its representatives started applying economy in until that time non-typical areas, and by this set in motion further progress of economic theories. The main aim of my work is to impartially recapitulate main representatives and sum up their works, metodology , ideas and views and particularlly reflect their general relevance for the Word of today.
|
|
Accounting for long-lived assets in internationally accepted accounting systems
Oplt, Lukáš ; Krupová, Lenka (advisor) ; Kudrnová, Lenka (referee)
This work deals with accounting treatment of tangible and intangible assets in International financial reporting standards (IFRS). It illustrates main problems and various methods when accounting for assets. Where deemed appropriate it indicates the accounting treatment of US GAAP. First chapter is concerned with general description of accounting harmonization and the Framework of IFRS. Second chapter deals with IAS 16 -- Property, plant and equipment. Third chapter identifies main differences between IAS 16 and IAS 38 -- Intangible assets focusing on issues related to the special nature of intangible assets. Fourth chapter works with annual reports and comes out with a statistic of IFRS methods and procedures adherence.
|
|
Analysis of the offers of tour operators in relation to chosen territory
Kotorová, Daniela ; Petrů, Zdenka (advisor) ; Straková, Ivana (referee)
Theoretical part of the thesis clarifies basic expressions from the area of tourism, spa tourism and of the activities of tour operators and travel agencies. There is a further characteristics of a chosen territory - Czech Republic, Slovakia and Hungary with the emphasis on spa tourism and wellness in this region. Practical part of the thesis analyses and judges spa and wellness stays according to chosen criteria presently offered by travel agencies and tour operators in those countries. Comparison and analysis of separate offers is stated by means of marketing mix.
|
|
Evaluation of advanced engineering use in tropics and subtropics
Mikuláš, Dalibor ; Prikner, Patrik (advisor) ; Kumhála, František (referee)
Modern agriculture systems use largely powerful machines with respect to its operation potential. This trend extends to countries with low levels of agriculture, where it can be found part of global agricultural production. Primarily soil properties affect the use of modern agricultural technology in specific regions; however, agricultural machinery manufacturers still adapt traction properties for specific climatic conditions. The aim of this thesis was to analyze and assess the current state of agricultural machinery in specific regions of the tropics and subtropics, where agricultural systems are focused on the production of crucial crops for food and industrial use.
|
|
Characterisation of the cell line TRAMP-C2 side population, mouse model of prostate cancer
Žlabová, Anna ; Reiniš, Milan (advisor) ; Šmahel, Michal (referee)
Side population is a minor subpopulation (SP) of some cell lines, exporting staining dye Hoechst 33342 out of their cytoplasm. It is discussed as a possible source of "cancer stem cells", "tumour initiating cells" or "metastasis initiating cells". However, broad literature suggest, that stemness and other privileged properties of SP are very variable between different cell types, cell lines and stage of disease. Cell lines TRAMP are the only widely available murine models for testing of prostate cancer therapy. We noticed in literature a mention about existence of 1-2% of cells constituting side population, but detailed characteristic have not been described until now. In this diploma thesis, we worked on characterisation of SP of the TRAMP-C2 cell line in comparison to other cells (nonSP). In the first part, we compared stem properties of SP and nonSP. We started with checking the existence of SP by its verapamil sensitivity. Using mRNA analysis, we showed that neither SP nor nonSP have increased c-Kit expression and that there are no differences in Bmi-1 expression. We found that SP is heterogenic mixture of CD24-CD44-, CD24-CD44+ and CD24+CD44+ cells, while nonSP is almost solely CD24-CD44+. We documented that SP and nonSP returned back to original SP ratio during cultivation. Then we showed on...
|
|
Recombinant aspartic proteases of blood-feeding parasites
Váchová, Jana ; Entlicher, Gustav (referee) ; Konvalinka, Jan (advisor)
The blood fluke Schistosoma mansoni and the hard tick Ixodes ricinus produce an aspartic protease cathepsin D which initiates degradation of hemoglobin, their key nutrient. First, in the presented work, the protocol for refolding and activation of the zymogen of cathepsin D from I. ricinus (IrCatD) was developed and optimized. In acidic pH the propeptide of IrCatD zymogen was removed by an auto-activation mechanism. Further, a kinetic assay with fluorogenic substrates was employed to study functional properties of IrCatD including pH optimum, substrate and inhibition specificities. Second, two isoforms of cathepsin D from S. mansoni (SmCatD) were produced using recombinant expression in E. coli. These recombinant proteases were isolated from inclusion bodies using affinity chromatography under denaturating conditions, and protocol for their refolding was developed and optimized. The studied aspartic proteases are pharmacological targets: inhibitors of SmCatD represent potential chemotherapeutics for the treatment of schistosomiasis, and IrCatD is a candidate antigen for the development of novel anti-tick vaccines.
|
|
Studium změn frakcí bílkovin zrna pšenice a ječmene po vybraných agrotechnických zásazích
Skácelová, Andrea
The aim of this bachelor work on the topic ,,Study of changes in protein fraction of grains of wheat and barley on selected agrotechnical interventions'' is a discovery of the influence the behavior of nitrogen and sulfur fertilizers on protein complex of wheat and barley. Biological properties and technological parameters of these crops are characterized. Furthermore, the work deals with the structure and content of each protein. Protein properties are reflected in the technological process and they influence the properties of the final products. Finally, this work shows the influences of nitrogen and sulfur on plants, their expressions of excess and deficiency. The emphasis is placed on the effect of these elements on the yield and quality of wheat and barley. This is verified by the experiment in Velká Bystřice near Olomouc city at year 2013.
|
|
Indefinte Determiners in French and its Czech Equivalents.
ŽEMLIČKOVÁ, Klára
The theme of the Bachelor´s thesis is the system of indefinite determiners in French language. The aim of my thesis is based on the literature to describe their morphological, syntactic and semantic properties, including their function in discourse and to try to find Czech equivalents of French expressions in a parallel body Intercorp. My thesis is divided into two main parts. The first theoretical part describes French indefinite determiners and the second, practical part of the work consists of analyzing them in parallel body Intercorp.
|
|
"The Image of New Zealand in Czech Press".
Čikarová, Klára ; Trampota, Tomáš (advisor) ; Křeček, Jan (referee)
The target of the diploma thesis "The Image of New Zealand in Czech Press" is to describe the ways of representation of New Zealand in Czech daily newspaper, namely MF Dnes, Lidové noviny, Hospodá ské noviny and Právo, in 2009. All the 490 articles dealing with the topic of New Zealand have been systematically examined by both quantitative and qualitative content analysis research methods. The quantitative content analysis deals with how the topic is represented among the newspaper mentioned above, measures the time line of its representation during the year and the space dedicated. However, the main concern is to recognize the main topics connected with New Zealand in the articles. The types of news (hard news and soft news) as well as the sources of news are discussed, too. The other subject of this thesis follows the actors and countries related to New Zealand. Next part concentrates on the linguistic analysis and interpretation of statements about this country and their possible positive or negative connotations. The main instrument used for the linguistic analysis has been an interpretation of evaluative expressions, metaphores, metonymias, irony, comparisons and other figures. Last part of this thesis emphasizes the importance of photographs illustrating some of the articles. All these...
|
|
Nutritional requirements of ticks.
PERNER, Jan
Ticks acquire nutrients only by a parasitic nature of feeding on animals, including humans. During this process, a wide array of pathogens is transmitted. Ticks of the Ixodidae family receive exactly one blood meal in each active developmental. Knowing the trophic dependence of tick metabolism on the host blood meal components may enable discovering processes essential for the tick physiology and development. Exploiting a membrane system of tick feeding and whole blood fractionation, we have revealed that adult ticks need to acquire host haemoglobin-derived haem so that they can produce viable larvae, and reproduce. Haem is not further catabolised in ticks, and iron is thus acquired via independent route with the host serum transferrin as a source molecule. Using RNA-seq, we compared transcriptome compositions between guts of blood- and serum-fed ticks. We identified fifteen gut transcripts that change their levels with respect to the presence/absence of dietary red blood cells. Glutathione S-transferase, one of the identified encoded molecules, shows a clear haeminresponsive expression at both transcript and protein levels. Its apparent haem-binding properties suggest that this protein is directly involved in haem homeostasis maintenance within the tick gut. The ultimate goal of such research is to identify and verify targets that, when blocked, would render the acquisition and/or distribution system of haem in ticks nonfunctional. This would represent a novel way of anti-tick interventions in veterinary and human medicine.
|
guest ::
