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Vliv chrómu na kvalitu ejakulátu a metabolismus sacharidů u plemenných kanců
Hánlová, Petra
Hánlová, P: Effect of chromium on semen quality and carbohydrate metabolism in bre-eding boars, Diploma Thesis MENDELU, Brno, 2015, s. 59 The aim of this thesis was to develop a literature search and experimentally de-termine the influence of mineral nutrition on boar semen quality. The thesis is divided into two parts. The first assesses the impact of the addition of chromium on semen qua-lity of breeding boars. The second part examines the influence of the addition of chro-mium on glucose and insulin levels in the blood of breeding boars. The experiment was conducted in Velké Meziříčí at the insemination center boars. The experiment consisted of 28 Duroc boars breed for 14 weeks. These boars were divided into 4 groups according to age balanced. In the control (n = 7) group (K), was chromium receiving 205 ug/kg/day. In the 1st group (n = 7) animals (CR1) was dose chromium even increased by 60.6 ug/kg compound feed for the second group (n = 7) boars (Cr2) of 121.2 ug/kg and 3. group (n = 7) boars (Cr3) was added chromi-um in an amount of 181.8 ug/kg compound feed. The addition of chromium to the semen quality of breeding boars too had a signifi-cant impact. During the first months of feeding chromium occurred in the control group to a decrease in ejaculate volume of 29 ml. In the group S3 during the experiment is bound to increase sperm concentration, but in the fourth taking under review decreased significantly compared to previous months. The difference between the third and fourth taking was 131.5 thousand/mm3. This difference is statistically insignificant, and could be caused by external influences or errors in nutrition. Sperm motility during certain months was below 70%. This ejaculate should not be used for insemination. In the second part of the experiment, the addition of the chromium significantly reduced glukose levels and insulin activity. The obtained results can not recommend feeding chromium breeding boars.
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Funding programmes and grants - are we good at using all possible means to gain funds?
Hrubčíková, Lenka ; Marková, Jana (advisor) ; Svoboda, Petr (referee)
TITLE: Funding programmes and grants - are we good at using all possible means to gain funds? AUTHOR: Lenka Hrubčíková DEPARTMENT: Centre of School Management SUPERVISOR: RNDr. Jana Marková ABSTRACT: My final thesis deals with methods of budget making for projects co-financed from ESF and other sources. It deals with description and categorization of individual grant programmes, methods of project management, categorization of costs depending on grant supplier. It warns against the most common mistakes in financing and carrying out projects. In the experimental part I try to find out how receiving grants influences attractiveness of the school and its economic situation and in which ways has grant financing been beneficial for schools. The aim of my thesis is to serve as a handbook for grant applicants and to give an overview of different possibilities of grant financing for secondary schools. The method used to write my thesis was mainly collecting information from various resources and from a questionnaire survey. My conclusion is that although the grant financing does not significantly improve the school finances and attractiveness, the schools should still apply for grants, because they provide important experience and better material equipment. KEYWORDS: grant, project, Leonardo da Vinci, grant...
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Effect of vegetation on snow accumulation and snow melt
Pevná, Hana ; Kocum, Jan (referee) ; Jeníček, Michal (advisor)
Effect of vegetation on snow accumulation and snow melt Abstract: This bachelor thesis analyzes the impact of physical-geographic factors on the physical properties and characteristics of the development of snow cover. Results published in the literature are compared with those obtained from experimental measurements in the upper Byst ice River basin in the Ore Mountains during the winter 2009/2010. The paper compares the evolution of snow cover for the actual land cover, forest and open areas. The research of literature and research conducted in the Ore Mountains proved that vegetation significantly affects accumulation and melting of the snow. The process of accumulation in the forest is influenced by snowfall interception in the treetops. Melting snow in a forest area slowed absorption and reflection of sunlight in the treetops. The bachelor thesis demonstrates that in the open areas the snow melted faster than in the forest growth. Keywords: snow cover, snow water equivalent, vegetation, Ore Mountains
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The Chronic Wound Therapy
Prosková, Zuzana ; Semecký, Vladimír (advisor) ; Martiník, Karel (referee)
The chronic wound is a secondarily healing wound, which didn't healed during 6 - 9 weeks despite adequate healing. Chronic wounds grow up from the acute wound crossing into chronicity as a result of an illness or an infection. The aim is to heal not only the defect but the illness as a complex. The suitable media of wound is necessary for re-issue of healing process. The balance and distribudion of MMPs and TIMPs is breaked in benefit of MMPs in non-healing wounds. In chronic wound liquids there are increased levels of MMP-2 and MMP-9. More increased proteases MMP-1, MMP-2, MMP-8, MMP-9, MMP-13, neutrophil elastese, uPA can be found directly in the chronic wound. That leads into substrates degradation which are necessary for healing (colagen, gelatin et al.). There was found out, that the decreasing of pH media leads to the decreasing of proteasis activity. The optimal pH of the media is 4 - 7. The epidermal growing factor is significantly more degraded and that leads into inhibition of proliferation of epidermal cells The experimental part target for healing by "wet" therapy. By all twelve pacients there were focused cleaning of wound, and regulation of a wound internal balance. The wound reparation was started. The contition is the right choise of "protection" for the concrete fase of healing....
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Measurement of amplitude and phase of ultrashort optical pulses by using nonlinear processes in optical fibres
Vraný, Boleslav ; Kaňka, Jiří (advisor) ; Karásek, Miroslav (referee) ; Boháč, Leoš (referee)
I confirm that I worked out this doctoral thesis independently and that I quoted all the literature used. Prohlašuji, že jsem tuto dizertační práci vypracoval samostatně a že jsem uvedl veš- kerou použitou literaturu. V Praze dne 21. 6. 2010 Abstract The thesis deals with the Frequency-Resolved Optical Gating (FROG) method of mea- suring ultrashort optical pulses. As a nonlinear process involved in the method we used cross-phase modulation in a microstructured optical fiber. The FROG device made of fi- ber pigtailed components fitted well the needs of our fiber optical laboratory. The output of the measurement differs significantly from FROG methods that use other nonlinear processes like second harmonic generation. For our FROG, the standard algorithms for reconstruction of the complex envelope from measured spectrogram failed. We therefore used a more robust genetic algorithm (GA) for the reconstruction. GA has several pa- rameters that affect its runs and we explored the influence of these parameters on the success of reconstruction of a number of test pulses and found the optimal set of these parameters. In this work, we present a general discussion of the FROG method and the standard reconstruction algorithms, the experimental setup we used, a discussion of the genetic algorithm, the technical details of our...
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The Influence of Dance Training on Mood and Feeling of People With Paraplegia
Kaplanová, Kateřina ; Fričová, Marie (advisor) ; Novotná, Viléma (referee)
Title: The influence of dance training on mood and feelings of people with paraplegia Objectives: The objective of this work was to detect using POMS questionnaire, whether the dance education has a positive effect on mood of people with paraplegia. Specifically, we focused on feelings such as depression, activity, anxiety and fatigue. Methods: The survey is a quantitative type using the POMS questionnaire (Profile of Mood State). Research has become a set of 40 people with paraplegia. 20 people were the control group and 20 persons were experimental group. Results: Dance education has significantly reduce the feeling of depression, anxiety, fatigue, and increase activity in patients with paraplegia. Dance in our case, show better results than any other sporting activity. Keywords: Dance education, paraplegia, mood, feelings, emotions, sports, music, adapted physical activities
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Development and applications of molecular dynamics for chiral systems
Kessler, Jiří ; Bouř, Petr (advisor) ; Fanfrlík, Jindřich (referee)
The Thesis deals with MD simulations of solutions of chiral solutes in chiral solvents. These solutions consist of 2,2,2-trifluoro-1-phenylethanol, 1-phenylethanol and 1-phenyl- ethanamine.The differences in NMR properties between different combnations of solvent and solute absolute configuration were modeled. Indeed, differences in radial distribution functions and conformer abundances of solute calculated by the WHAM method were found. These results correlated with experimental differences in NMR shifts. Additionally, a method of cluster preselection was developed. It significantly decreased the amount of clusters needed for computations of NMR shieldings and hence the computer time. Keywords: chirality, molecular dynamic, nuclear magnetic resonance
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Germ cell apoptosis induced by artificial cryptorchidism.
Komrska, Josef ; Semecký, Vladimír (advisor) ; Langr, František (referee)
Abstract. We had studied morfological and histological changes of Wistar rat germinal epithelium after experimentally induced cryptorchidism. Our experiment had lasted seven days. Cryptorchic testes was injected by solution of MDOCTM. We used also tissues which was taken from other comparable studies but without MDOCTM for histological evaluation of shorter time intervals. Both size and weight was significantly reduced in cryptorchid testes compared to contralateral and control testes (22.4% and 52.6% respectively). We recorded degenerative changes of germinal epithelium including epithelial desintegration and release of immature and apoptotic cells, which was found in epydidimal tubules, even in one hour interval. Six days after operation, multinucleated cells and vacuolization of epithlelium also appeared. Seven days after operation (and aplication MDOCTM) we found a significant degeneration of germinal epithelium comprising features from vacuoles to apoptotic cells. A large number of macrophages also appeared in this interval. We didn't record any degenerative features in contralateral and control testes.
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Microstimulator
Nedvědová, Marie ; Rozman, Jiří (referee) ; Chmelař, Milan (advisor)
The theoretical part of the thesis deals with the explanation of the actions that occur during the stimulation of tissues with the electric current. A significant analogy with electrical circuits is used to describe the phenomena at the molecular and cellular level. The models of membrane and cell are necessary for understanding the behaviour of more complex structures, such as tissues and organs. A considerable attention is paid to the conditions of electrical stimulation which bring about response in the stimulated area. Next, the cumulative effect of the subthreshold stimulation is analysed. The mechanisms of common treatment effects of the electrotherapeutic methods are outlined. The research results in the practical part of the thesis – the design for a microstimulator. Properties of the microstimulator and compliance with standard requirements are verified by testing the electromagnetic compatibility and electrical safety, conducted by the Institute for testing and certification, JSC. The effects of microstimulation on living organisms are experimentally investigated on horses, in collaboration with the Veterinary and Pharmaceutical University. For the first time, thermodynamic sensors are used for the objective assessment of the microstimulation therapeutic effect. These miniature sensors are placed on the horse´s front legs and monitor the changes in thermal activity while only one limb is really stimulated and the other is just considered as a reference. Comparison and statistical evaluation of the measured signals could provide a more detailed view of the thermal changes within the stimulated area, which is significantly related to blood circulation in limbs, and with the support of the reduction of edema. The course of the experiment which deals with the effect of microstimulation on edema of the horse´s legs caused by minor injuries (tendinitis, sprains, etc.), is documented in photographs or videos that are significant for possible evaluation of the effectiveness of the stimulation in this application.
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Unconsciousness of unknown etiology in first contact
KOŠŤÁL, Jan
This Bachelor Thesis deals with the topic: "Unconsciousness of unclear etiology upon the first contact of the emergency services with a "patient". The causes of unconsciousness are generally very diverse, which means that the exact cause can remain unclear during the first contact and during the phase of pre-hospital emergency treatment.Duringthelaterphaseof hospital care,more time and more sophisticated ways of examination are available to clarify the exact cause of unconsciousness. In the theoretical part of this Thesis, was a summarize the basic knowledge on consciousness and on the causes of impaired consciousness or unconsciousness. Next is a describe the diagnostics of unconsciousness during the pre-hospital medical care and present the practical procedures that need to be followed by paramedics taking care for unconscious patient. The most often causes of unconsciousness are: hypoglycemia, intoxications, craniocerebral injuries, hypoxia linked to cardiopulmonar resuscitation, bleeding to brain and brain stroke. From the point of view of the paramedic, the most important is to make early distinction between the states linked to intoxication or metabolic disorders and the states linked to intracranial injuries, bleeding and stroke. While the former states require immediate intervention by paramedic, the later states require neurosurgical intervention in the hospital. In the experimental part of this Thesis, was mapped the practical knowledge of paramedics on pre-hospital medical care for for unconscious patient. The mapping was conduct using the technique of standardized semi-structured dialogues with 14 respondents paramedics selected from all seven regional stations of the Emergency services of the South bohemian district, Czech Republic. The respondents differed in age, duration of their professional career, and level of education. All respondents answered 16 questions. All their answers are presented in the Thesis in the full form as well as processed in the Table form. In investigation proved practical difficulties with the diagnostics of unconscious patients. The results indicate that more attention should be paid by paramedics to obtaining full and correct anamnesis plus general examination of the patient. Based on early diagnosis, paramedics can decide on therapeutical procedures and on directing the patient to relevant hospital. In case of patient with secured life-functions, it is recommended to direct the patient to specialized healthcare facility, which shortens the interval between injury and targeted treatment. Results also point toward the general need that paramedics should undergo regular training in new methods and trends in paramedical care. Using of new methods of capnometry is one case where more widespread usage in paramedical practice could bring significantly better results.
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