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The reflective effect of manipulative therapy on blood pressure.
Martínek, Josef ; Bitnar, Petr (advisor) ; Slabý, Kryštof (referee)
The topic of the thesis is The reflective effect of manipulative therapy on blood pressure. The aim of the thesis is to summarize current knowledge, which talk about the relationship between the ma-nipulative therapy and the changes of blood pressure. One of the purpose of the thesis is to clarify the using of manipulative therapy in the treatment of arterial hypertension. In the thesis another methods of manipulative therapy are discussed to give broad overwiev and to have a posibble to comparison. Powered by TCPDF (www.tcpdf.org)
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Distant effects of muscle electrostimulation
Koláček, Michal ; Slabý, Kryštof (advisor) ; Demeková, Júlia (referee)
This work is trying to identify possible non-stimulatory effects and distant effects of muscle electrostimulation musculus quadriceps femoris based on a literature search. Furthermore evaluates the influence of High Tone Electrical Stimulation (HTEMS) muscles of lower limbs on the activity of the autonomic nervous system, expressed by heart rate variability, a spectral power in the individual frequency bands. Randomized crossover study involved 20 healthy subjects (12 men and 8 women), average age 24.6 ± 5.6 years. Heart rate variability was evaluated before application of HTEMS and immediately after. Measurements were performed with electrostimulator HiToP 191. The results did not show statistically significant increase in spectral power in the individual frequency bands. The study also deals with the reproducibility of measurements of sensitive and motor threshold for electrostimulation HTEMS method, which was confirmed. Powered by TCPDF (www.tcpdf.org)
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Circadian regulation of glucocorticoid secretion
Tejkal, Karel ; Sumová, Alena (advisor) ; Soták, Matúš (referee)
Glucocorticoids belong to a family of steroid hormones synthesized in the adrenal gland. They fulfill a variety of functions related to metabolism, immune response and ontogenesis. Glucocorticoids function as the end-effector of hypothalamic-pituitary-adrenal (HPA) axis and as such, their levels in blood are elevated after exposure to stressors. The basal levels of glucocorticoid also show a pronounced diurnal rhythm, suggesting involvement of the circadian clock in the regulation of HPA axis. Studies have shown that other regulatory mechanisms apart from the HPA axis are involved in regulation of diurnal glucocortioid secretion. The disturbances of the regulatory mechanisms may lead to serious pathological conditions. This thesis describes the rhythmic nature of glucocorticoid release and mechanisms by which the circadian clock exerts its influence over the rhythm. Thereafter, the feedback of glucocorticoids onto the clock system is briefly explained. Finally, some examples of a role of abnormal glucocorticoid secretion in selected pathologies are provided.
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Autonomic nervous system and its relationship to functional disorders of the muscle
Marčišová, Hana ; Čech, Zdeněk (advisor) ; Slabý, Kryštof (referee)
The aim of this paper was to summarize the current knowledge of function and regulation of autonomic nervous system (ANS). We wanted to assess possible involvement of ANS in changes of muscle tension. Sympathetic nervous system affects the sensitivity of somatosenzory afferention, thus effecting the function of whole nervous system. Exists evidence about ANS effect on cutaneous afferents activity as well as muscle spindle afferent activity. Sympathetic modulation of proprioceptive information from muscle spindles may influence α motoneuron excitability. ANS may affect muscle tonus regulation. The selective activation of trigger point (TRP) during heightened muscle sympathetic efferent activity (MSNA) was proved. This supports the idea that the sympathetic nervous system can directly contribute on maintaining of the TRP and myofascial pain syndrome. Powered by TCPDF (www.tcpdf.org)
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Methods for the evaluation of heart rate and arterial blood pressure variability
Sedláčková, Gabriela ; Halámek, Josef (referee) ; Leinveber, Pavel (advisor)
The bachelor thesis deals with methods for description of heart rate variability and arterial blood pressure. An important mechanism for maintaining homoeostasis in the body is so called baroreflex feedback loop, which allows for a short-term regulation of blood pressure. The thesis contains description of methods which are currently used for baroreflex sensitivity evaluation. Analysis in time domain as well as in frequency domain was done using programs in Matlab environment. At the end of the thesis the influence of ventricular extrasystoles on output parameter is evaluated.
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Influence of autonomic nervous system in the inducibility of atrial fibrillation.
Šrutová, Martina ; Provazník, Ivo (referee) ; Kolářová, Jana (advisor)
Cílem této práce je zjištění změn předcházejícím fibrilaci síní. Pozorována je rovnováha mezi sympatikem a parasympatikem. Do experimentu výzkumného ústavu Cleavlendské kliniky bylo zapojeno šest psů různých ras. Signály EKG byly získány Holterovským 24hodinovým monitorováním. Pomocí 40 vysokofrekvenčních impulsů (TI) byla každých 30 minut vyvolávána AF. Z 24hodinového signálu byly extrahovány kratší epizody. Každá z těchto epizod obsahovala 10 minut předcházejících TI a 3 minuty následující po TI. Desetiminutové epizody byly zpracovány automaticky, byly detekovány QRS komplexy a RR intervaly a vypočteny HRV parametry. Přítomnost a délka trvání AF byly zjištěny manuálně z tříminutových intervalů následujících po TI. Byla-li vyvolána AF o délce trvání kratší než 30 sekund došlo ve srovnání s epizodami bez výskytu AF k významným změnám tří HRV parametrů. HF parametr poklesl pro epizody s výskytem AF. LF parametr byl naopak vyšší v epizodách s AF. Pro AF delší než 30 sekund nebyly významné změny pozorovány. Změny v epizodách s krátkou AF mohly být způsobeny změnami vlivu sympatiku a parasympatiku. Ke vzniku dlouhých AF je pravděpodobně zapotřebí i jiného vlivu, který nemusí nutně souviset s nervovým systémem. K dalším analýzám je zapotřebí většího množství signálů.
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