National Repository of Grey Literature 1,909 records found  1 - 10nextend  jump to record: Search took 0.06 seconds. 

Strategy business transformation from the small to medium enterprise level
LIŠKOVÁ, Eva
The aim of the diploma thesis is to analyze the current developments in the enterprise, consider the future business at a medium-size, to determine the potential market and propose the optimal marketing policy of the company. The main objective is to draft recommendations to expand business and increase the competitiveness of the transformed company. The work is to monitor the development of enterprise in terms of finance, purchasing, production, storage, distribution, human resource management and marketing. It is also analyzed the internal environment, which includes financial analysis and an analysis of resources and competencies. Analysis of the external environment involves an analysis of competition, analysis of the attractiveness and STEP analysis. SWOT analysis summarizes the enterprise internal factors (strengths and weaknesses) and external environmental factors (opportunities and threats) analysis of the two. The analysis and evaluation is used of the data from the years 2004 to 2008. The result of this dissertation is the finding that the company is able to transform the medium-sized enterprise within two years, which take 10 - 12 employees. However, it should be to reduce the indebtedness of the company and is currently disinvest. To increase the competitiveness and the increase in sales on the market introduces a new product and using the Czech Trade Agency reach new foreign markets.

Modelling of flow over a backward-facing step in streams with various turbulence level
Příhoda, Jaromír ; Sedlář, M.
Turbulent flow over a backward-facing step in streams with a various turbulence level was numerically simulated using software ANSYS CFX-5. Numerical solution carried on with the two-equation SST model and/or with a k-omega based Reynolds stress model was compared with experimental data obtained for three different values of free-stream turbulence level. The predicted length of the recirculation region corresponds well with experimental data but the dependence of the ratio xr/h on free-stream turbulence level is smaller.

Monitoring Students' Activity at Omska's Gymnasium
Kvasilová, Anna ; Kovář, Karel (advisor) ; Šeflová, Iva (referee)
Title: Monitoring Students' Physical Activity at Omska's Gymnasium. Purpose: Measure the physical activity level of students at Omska's Gymnasium to determine if the average student meets the prescribed physical standards. Tasks: study the literatura chaose appropriate measurement concepts for evaluating physical activity - take measurements using pedometers - define the research sample monitor through the use of pedometers and informal interviews perform statistical data analysis - compare and contrast the collected data against the theory Methods: The information collected, through the use of pedometers and supporting informal interviews, provided an overview of how students spend their free time and of their nutritional habits. Results: The results proved that the average value of the steps did not reach the prescribed standards. Keywords: physical activity, physical activity of children, prescribed limits, steps

The effect of analgesics and their combination with neurotropic drugs on pain and brain mediators
Soukupová, Marie ; Kršiak, Miloslav (advisor) ; Farghali, Hassan (referee) ; Rokyta, Richard (referee)
The first aim was to investigate changes in analgesic efficacy of several analgesics in combination with selected drugs affecting nervous system after systemic administration. The second aim was to ascertain changes of levels of pain mediators in vivo in supraspinal brain structures (in periaqueductal gray matter, central amygdala, striatum) in pain and under the drug influence. The analgesic efficacy of combinations of analgesics with neurotropic drugs was investigated in the writhing test in mice. Interactions between analgesics and neurotropic drugs were evaluated by the isobolographic analysis, which enables to distinguish the supra-additive (synergistic) interactions from solely additive and sub-additive ones. A possible negative effect of neurotropic drugs on motor functions was determined in the rota-rod test in mice. Changes of levels of pain mediators in the brain during pain and under the drug influence in rats were measured by microdialysis in vivo coupled with a high performance liquid chromatography. A model of inflammatory pain induced by intraplantar injection of carrageenan and a model of neuropathic pain produced by a spared sciatic nerve injury model were used in rats. We evaluated pain in plantar and von Frey filament test. Our microdialysis experiments revealed that inflammatory pain...

Analysis of the levels of morphine in the systemic circulation when abuse / / natural opium poppy clients and contact centers in the region of Central Moravia
Kučeravcová, Jitka ; Klusoňová, Hana (advisor) ; Pourová, Jana (referee)
This Rigorous Thesis concerns the problems with the natural opium abuse in the region of Central Moravia. It is based on the questionnaire analyses, which were held in The Contact Centre Plus in Kroměříž and in The Contact Centre Kappa in Přerov in the period from June to August 2007. Further the results of Diploma Thesis The Questionnaire Analysis of Natural Opium Abuse in Olomouc and Prostějov Region, from the year 2007, are used in this work. The results of the Diploma Thesis come from the questionnaire analysis, which was held in The Contact Centre Walhalla in Olomouc and in The Contact Centre Želva in Prostějov in the period from May to July 2006. 71 clients from all mentioned contact centres took part in this resarch (22 from Kroměříž, 17 from Přerov, 20 from Olomouc and 12 from Prostějov). ). All the results from the Contact Centres Walhalla and Želva are written in the above mentioned Diploma Thesis. Only those clients with the experience of opium abuse were added to the group of respondents. After having analysed the results from all the four centres, we found that the average age of Kroměříž (KM) users is 26,4 years, of Přerov (PŘ) users it is 28,8 years, of Olomouc (OL) users 25,6 years and of Prostějov (PV) users it is 24,4 years. More than a half of all the clients from the centres are...

Monitoring the effect of atorvastatin on the expression of endoglin / / and endothelial NO synthase (eNOS) in mouse model of atherosclerosis
Uhlárová, Iva ; Nachtigal, Petr (advisor) ; Štaud, František (referee)
Atherosclerosis, or sclerosis of arteries, is a degenerative disease of arteries. Sometimes it is called "the disease of 20th century". ApoE/LDL - receptor double knockout mice represent a new animal model for study of atherogenesis, which is characterized by severe hyperlipidaemia and atherosclerosis. Statins (or competitive inhibitors 3-hydroxyl-3-methyl-glutaryl-coenzym A-reductase) currently belong to the most efficient and the most useful hypolipidemic drugs for all over the world. They decrease mainly levels of total cholesterol and LDL cholesterol. The aim of this thesis was to describe the expression of endoglin in atherosclerotic plaques in apoE/LDL-receptor deficient mice. Moreover we wanted to determine endoglin colocalization with eNOS and the effect of atorvastatin treatment on the expression of both molecules. ApoE/LDLR-deficient mice on were subdivided into 2 groups. The control group of animals was fed with the western type diet. The same atherogenic diet was used in ATV group, where atorvastatin was added to the atherogenic diet at the dosage of 100 mg/kg per day. The results of this thesis confirmed the expression of endoglin in atherosclerotic lesions in ApoE/LDLR-deficient mice. The expression of endoglin was located on the aortic vascular endothelium and in other smaller...

The Introduction of Contact Ecotoxicity Tests for the Assessment of Terrestrial Ecosystems
Modlitbová, Pavlína ; Kráčmar, Stanislav (referee) ; Beklová, Miroslava (referee) ; Demnerová, Kateřina (referee) ; Vávrová, Milada (advisor)
This dissertation thesis is focus on using toxicity tests with testing organism - terrestrial isopod Porcellio scaber. This organism is use for toxicity assessment of selected anorganic compunds which could contaminate terrestrial ecosystem. This organism was selected for several reasons - sophisticated test methodology; well known biology of these animals and their ecological relevance. Besides classical endpoints such as mortality, change in mass of test specimens and the effect of the presence and concentration of contaminants onto food consumption; we monitored changes in the morphometric characteristics at the level of tissues and cells, the cytotoxicity and possibly bioaccumulation in various parts of the body of the organism. Selected test substance in this thesis were nanoparticles and inorganic salts. Wherein for chosen gold nanoparticles was carried out a complete study presents several levels of organization of living matter (organism, tissue, cell). For selected salts compound, this study was carried out on the behavior of organisms and classical endpoints.

Social transformations of the Czechoslovak village in the first half of the fifties - example of the district of Sedlcany
Čermáková, Hana ; Rákosník, Jakub (advisor) ; Pullmann, Michal (referee)
This thesis seeks to capture the changed political climate after 1948 in the Czechoslovak village. It examines one political Sedlčany district, which was very specific in term of industrial backwardness and depopulation after World War II. It consisted of a specific marginal share of industrial production and low population density. The starting point is the work of Communist propaganda at the district level. The second chapter deals with the theoretical definition, especially socio-cultural propaganda as a concept, is looking for its solution, goals and different definitions. Another chapter deals with general history Sedlčany and regional specifics. The fourth and fifth chapter focuses on the local structure of the district committee and the lower components of the Communist Party of Czechoslovakia in the region and social transformation of society as a whole in the first half of the fifties in the country. The second part of the thesis is devoted to defining the scope of direct advertising strategies and resources. Most of the work deals with propaganda, describing the district level, monitors the work of the district committee of the Communist Party of Czechoslovakia, analyzes the rural district newspaper articles and records the memories of witnesses. The remaining chapters deal with the practical...

Application of logistics processes in online shop
MELENOVÁ, Štěpánka
The aim of this bachelor paper was to evaluate an activity of the company TV Products CZ, Ltd. during a calendar year, assess the advantages and disadvantages of online shopping from the customer's view and compare it with traditional shopping at stores. In the theoretical part, the terms of e-shop and store were explained. This part was also occupied with the e-shopping history and development. Then this part was focused on the payment methods and the level of the customer services. In the practical part, the selected company was introduced at first and then all activities from orders to goods delivery to customers were monitored. It was realized by personal visit to this company. Through this visit the shortcomings were detected and the measures which lead to improvement and customers' satisfaction were created. The company should pay attention to these shortcomings and focus on their removal

Analysis of the trend of household debt in the Czech Republic in the period of 2000 - 2011
Kučerková, Zuzana ; Kotýnková, Magdalena (advisor) ; Pavlíček, Tomáš (referee)
The aim of this thesis is to analyze the level of household debt in the Czech Republic in the period from 2000 to 2011, causes of indebtedness and analysis of use of personal bankruptcy. The theoretical part is focused on economic, social and legal aspect of the issue of household debt. The practical part consists of analysis of statistical data describing the development of the level of household debt in the years 2000 - 2011 with the help of monitoring absolute and relative measuring indicators. Further analysis is carried out using of personal bankruptcy in the Czech Republic in the period from 2008 to 2012. On the basic of these analyses, this work suggests the ways to improve the situation of over-indebted households. Special emphasis is placed on the relatively new of vulnerable households - pensioners and it is also defined the causes of this phenomenon.