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Cost-effectiveness model of universal screening for thyroid disorders in pregnancy for the Czech Republic
Tužil, Jan ; Bartáková, Jana (advisor) ; Brennan Kearns, Pavla (referee) ; Babeľa, Róbert (referee)
Model nákladové efektivity plošného screeningu poruchy funkce štítné žlázy v těhotenství pro Českou republiku Cost-effectiveness model of universal screening for thyroid disorders in pregnancy for the Czech Republic Disertační práce English Abstract Introduction: Subclinical hypothyroidism affects approximately 5% of pregnant women in the Czech Republic and is associated with a number of health risks for both mother and child. The negative effects can be prevented by effective and safe hormone replacement therapy. Although subclinical hypothyroidism can be diagnosed solely by blood tests, only 45% of pregnant women in the Czech Republic are currently tested. Thyroid function screening (thyrotropin; TSH) can be accompanied by thyroid autoimmunity testing (anti-thyroid peroxidase antibodies; anti-TPO) to predict increased risk of postpartum thyroiditis. Aims: The aim is to model the cost-effectiveness, budgetary impact and impact on routine practice of the introduction of universal TSH screening (versus the current state of things) and an addition of the universal anti-TPO screening (versus TSH screening alone). Method: The cost-benefit ratio, budget impact, and impact on routine practice were modelled using a decision tree for implementation of the TSH test and a nested decision tree for the addition of the...
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Comparison of T-Mobile, Vodafone and O2 brand strategies: effectiveness of communication and adaptation of trends addressing Gen Z
Sedláčková, Barbora ; Rosenfeldová, Jana (advisor) ; Houdek, Petr (referee)
Telecommunications technology surrounds us every day. Generation Z, along with Millennials, are the so-called digital natives and currently represent the strongest direct and indirect buying power. Companies have thus shifted their communications in a big way to the digital space in an effort to effectively target and reach this age group. This bachelor thesis compares the communication strategies of telecommunication brands T-Mobile, O2 and Vodafone on social media platforms, specifically Facebook, Instagram and TikTok. It focuses primarily on the effectiveness of communication and the ability to adapt trends that appeal to Generation Z. The theoretical part of this thesis introduces and explains basic terms such as Generation Z, trends, social networks and influencer marketing, which are key to this thesis. In the methodological part, the author presents four set research questions, which are answered in the conclusion of this thesis. The research part of this thesis is divided into two parts - an analysis of telecommunication brands' communication on selected social media platforms, which focused on the time period from August 1, 2023 to February 29, 2024, and a quantitative questionnaire survey. The research part of this bachelor thesis shows that the T-Mobile brand performed best not only in...
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Effectiveness of activated carbon in removing pharmaceuticals from water
Kučera, Jakub ; Lukášová, Daniela (referee) ; Biela, Renata (advisor)
The bachelor thesis deals with micropollutants in drinking water sources, specifically pharmaceuticals and the possibilities of their removal from drinking water. The theoretical part describes the possible pathways for the supply of pharmaceuticals to water sources, the most common types of pharmaceuticals found in water sources and the options for their removal. The practical part of the bachelor thesis is devoted to the concentrations of pharmaceuticals in raw water taken for drinking purposes and comparison of the properties of original and new activated carbon in their removal. Finally, the removal efficiency of selected quality parameters is compared.
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Monitoring the effectiveness of the Hosov water treatment plant technology on the quality of drinking water
Gloc, Tomáš ; Látal,, Milan (referee) ; Biela, Renata (advisor)
This bachelor thesis deals with the monitoring of the effectiveness of the Hosov water treatment plant technology on the quality of drinking water, where an analysis of the received data was performed with a subsequent calculation of the efficiency for the technological line of the Hosov WTP in the periods of interest. The theoretical part is processed in the form of research regarding the necessary knowledge and context (resources, legislative limits, technological treatment processes) in contrast to water treatment. In the practical part, two periods of interest were chosen. The first comprehensive time period from the beginning of 2020 to the end of 2022 and the second time period, where the years 2012, 2019 and 2022 were chosen through a longer time interval. For the periods of interest, 6 indicators were monitored (color, turbidity, nitrites, CHSKMn, iron and manganese). Monitoring the concentration of indicators in raw water in selected periods enabled the assessment of changes in the quality of resources over the years. Concentrations of indicators in raw water and then in treated water were used to calculate and evaluate the overal efficiency of the technological line of Hosov WTP.
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Grate Biomass Boiler
Kleinová, Martina ; Křemínský, Pavel (referee) ; Lisý, Martin (advisor)
The main content of the thesis is the design of a steam boiler for biomass of smaller outputs of 6 MW. The fuel of the boiler was chosen spruce wood chip by 40% humidity. The parameters of the superheated steam are a temperature of 420 °C and a pressure of 40 bar. The work includes stoichiometric and thermal calculations, which are determined by fuel composition and output steam parameters. In the annex to the thesis, individual heat-exchange surfaces and the dimensional design of the boiler, including the layout, are marked. This work also features calculations of pressure losses on the part of both media.
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Preparation of a laboratory exercise focusing on hydrogen energy storage
Mistrová, Jana ; Vanýsek, Petr (referee) ; Bača, Petr (advisor)
This diploma thesis describes the preparation of a laboratory experiment focused on hydrogen storage capacity. The experiment deals with hydrogen production, fuel cells, the evaluation its efficiency and hydrogen consumption within a fuel cell. The first part of the thesis is devoted to the energy storage systems, particularly chemical energy storage and hydrogen production. The next part explores fuel cell technologies. Following this, the thesis describes the experiment's preparation, equipment, and fuel cell activation. The final part focuses on the laboratory materials and the report.
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A comprehensive technical economic analysis of an electric car and a hydrogen vehicle
Lašák, Ondřej ; Sitek, Tomáš (referee) ; Elbl, Patrik (advisor)
Modern human society has undergone rapid technological development, and, as a result, humanity has begun to change the climate of planet Earth. The result is rising average temperature across the planet and some areas are threatened to become uninhabitable. One of the causes of global warming is the high CO2 emissions arising, among other things, from transportation. That is why transport is being diverted from fossil fuels to alternative energy carriers such as hydrogen or to direct usage of electricity. The aim of this work is to compare a hydrogen car and a battery electric car in terms of emission and energy requirements. In the last part, the economic costs of the transformation of passenger transport to these new fuels are approximated. The comparison includes current conditions and outlook to the future.
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Application of cooled Exhaust Gas Recirculation on modern gasoline engines
Bazala, Jiří ; Bauer, František (referee) ; Tůma, Jiří (referee) ; Píštěk, Václav (advisor)
This document describes the possibilities of increasing the efficiency of an internal combustion engine using cooled EGR (exhaust recirculation system), water injection and their combination. To investigate it the engine model was calibrated based on the experiment. It was investigated the effect of the externally cooled EGR system on key engine parameters such as efficiency, specific fuel consumption, performance and others on this model. Here it was concluded that EGR system has unsatisfactory parameters in terms of the ratio of achieved results and complexity. Therefore, the water injection model was tested on the model and compared with the EGR system. The engine model with water injection was evaluated as more advantageous. Therefore, it was decided to invest available sources to the experimental vehicle with water injection and verify experimental results with model. Using of both systems, the EGR system and water injection, and ideally with the possibility of pre-ignition, appears to be the most suitable combination with regard to the observed parameters.
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Energetic model of linear axis with ball screw and servodrive
Sládek, Vojtěch ; Tůma, Jiří (referee) ; Huzlík, Rostislav (advisor)
The aim of the thesis was to study the Energy Models of Linear Axes with Ball Screws and Servo Drives, to analyze the individual parts of the axis with respect to losses, the methodology of calculating the losses on the electrical part and the mechanical part of the drive and creating a complex algorithm that calculates the energy consumed for the specified motion. The thesis is divided into a theoretical and practical part, where the theoretical part is divided into the treatise on the electrical part of the axis and its losses and the part that deals with the mechanical part and its losses. The calculation is divided into the basic verification algorithm and the calculation on the given example. Each calculation is calculated for both linear acceleration and S-curve acceleration. For both types of acceleration, the result of energy and its course over time is also the waveforms of position, velocity, acceleration, angular acceleration, moments, powers, power, speed and currents over time.
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