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The effect of cold exposure on regeneration in skeletal muscle
Novotná, Veronika ; Kašík, Petr (advisor) ; Vašek, Daniel (referee)
Cold is a stressful stimulus to which the body responds with an extensive physiological response, making it important to understand its complex effects. Skeletal muscle is an important thermoregulatory organ and helps maintain a constant body temperature by both shivering and non-shivering thermogenesis. At the same time, it has a considerable regenerative capacity that is modulated by the inflammatory immune response. This paper summarizes the effects of cold on skeletal muscle regeneration and the inflammatory response that is triggered after intense exercise or skeletal muscle injury. The inflammatory response is essential for the successful completion of skeletal muscle regeneration, and if it is impaired, it can have a negative effect on muscle tissue recovery. The balance between the pro-inflammatory and anti-inflammatory phases of the immune response, which is determined by the presence of specific immune cell populations and cytokine release, is crucial. Cold exposure is generally accepted as an effective strategy to improve skeletal muscle regeneration, but the molecular basis of this effect is not fully understood, and thus the observation of the effect of cold on skeletal muscle regeneration is still a actual topic. Keywords: cold exposure, inflammation, skeletal muscle, regeneration,...
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Steam turbine for biomass power plant
Urbánek, Roman ; Fiedler, Jan (referee) ; Kracík, Petr (advisor)
The master's thesis deals with the design of a condensing steam turbine for a biomass power plant with off-takes for heating heaters with a temperature drop of 60/80 °C in summer and 70/125 °C in winter, and off-takes for low-pressure regeneration. The nominal thermal output of the heat exchangers is 0-10 MWt in summer and 0-50 MWt in winter. The thesis includes a detailed design of the flow parts of the steam turbine, from the design of the control stage, the staged part of the turbine, and the strength verification of individual stages to the design of the balancing piston, sealing system, and bearing design. In conclusion, the operational characteristics of the proposed steam turbine are depicted.
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CO2 capture in a spray column using different atomization techniques
Klíma, Petr ; Bělka, Miloslav (referee) ; Malý, Milan (advisor)
Carbon dioxide capture (CO2) can be a key step in the fight against global climate change. One of the promising tehcnologies for CO2 capture is the spray column. This diploma thesis investigated its potential through a review of available literature and laboratory experiments. Specifically, the work included an overview of absorbents and nozzles. Furthermore, research was conducted on the geometric and operational parameters of spray columns and other similar devices used for CO2 absorption and desorption. These findings led to the construction of a spray column and the execution of experiments. The effect of the type of nozzle used, as well as the effect of CO2 concentration in the supplied gas, the effect of atomization pressure and the effect of temperature on the absorption efficiency in the spray column were investigated. Regeneration experiments were also carried out in a spray column and then on a smaller scale in a steel cylindrical vessel.
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Analysis of already revitalized brownfield in the Czech Republic
Pilčíková, Adéla ; Landa, Karel (referee) ; Pavlovský, Tomáš (advisor)
The subject of the bachelor's thesis is "Analysis of a Revitalized Brownfield in the Czech Republic." The thesis is divided into two parts. The first, theoretical part, focuses on introducing the concept of brownfields, their history, the perspective on revitalization in the Czech Republic and neighboring countries, and an analysis of their frequency within the republic. In the second, practical part, specific analyses of a selected brownfield from various perspectives are conducted — urbanistic, ecological, economic, and sociological. Furthermore, suitable uses and future development of the site are outlined, considering current trends in sustainability, smart and developing cities, as well as potential infill or structural modifications.
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Human ecosystem
Lapšanská, Gabriela ; Vitková, Lubica (referee) ; Mléčka, Jan (advisor)
The diploma thesis focuses on the conversion of a railway brownfield. Abandoned and contaminated areas are currently becoming valuable resources for ecological sustainability and contribute to improving the quality of life in the city. The aim of the work is to find alternatives while respecting the existing construction with minor architectural interventions. Connecting the area with the urban structure, meaningful functional fulfillment, and year-round programming ensure the pulsation of a ‚living center‘ in the emerging landscape forest park.
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ZBROJOVKA FACTORY BRNO
Kraut, Jan ; Stuchlík, Aleš (referee) ; Havliš, Karel (advisor)
ZBROJOVKA BRNO - Opportunity for the city Strategies for Zbrojovka Brno, the third largest brownfield in the city. Urban policy and the process of integration of the site into the city and connection with his organism. Creating a territorial strategy or tactical urbanism procedure that tries successive interventions re- incorporate this into the organism of the city , in a way that fully reflect the needs , possibilities and polarity in the territory. It is essential that the established process allowed for long-term gradual regeneration, which can be interrupted by economic pressure, and in its every moment of creating a working environment that sudden interruption of restorative work in their stride. The entire process of restoring the site is divided into several phases , but at each flexibly connected and can run such a large area partially independently . Based on the current state of the complex, which is gradually opened , are removed objects that are in disrepair , and those that hinder the development of the area and its smooth functioning. Subsequently, traffic control , area connected to public transport. As a result, the situation will stabilize and rehabilitate the total area of the factory and its surroundings. All through individual interventions in its structure and public space. The whole process is documented on the basic objectives and approaches of the phases that are subsequently documented reference interventions and achievements typical of the condition of the site. All complemented by an analysis of the phenomenon of the basic tasks of rehabilitation of the site.
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MOSILANA FACTORY BRNO
Cyrnerová, Jana ; Hýl, Petr (referee) ; Havliš, Karel (advisor)
Subject of master thesis is urban nad architecture study of former textile factory area and land along the street Křenová. The main theme of the solution is integration and rehabilitation of the contemporary building into organism of the city and susceptible addition of new masses which is based on the principles of compact city. Emphasis is also put on increasing throughput and quality of public spaces, which is missing nowadays. In detail I am focused on new buildings – the residential house on the green parking platform, row houses along the river Ponávka and alternative conversion of fomer Dye House into Mother Center. The aim is to propose some alternative to currently inappropriate land use and invention based on the Regional Plan.
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Air conditioning in the theater
Lenhart, Marek ; Vlček, Petr (referee) ; Blasinski, Petr (advisor)
The Bachelor’s dissertation is divided into three parts: theoretical, computational and design. The theoretical part is focused on heat recovery systems in air condition. The computational and project part deal with the design of air ventilation, heating and air conditioning theater.
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Conversion of Vlněna boiling-room
Gebauer, Pavel ; Štikar, Jaroslav (referee) ; Nový, Alois (advisor) ; Donaťáková, Dagmar (advisor)
The Bachelor thesis deals with the reconstruction and restoration of the building which is part of Vlněna complex in Brno. Location, in which is the object situated, is undergoing an extensive/large modernisation. Almost all historic buildings of this industrial complex are being replaced with high-rise administration blocks which deviate from historical context of the area. One of those exceptions, is also the object of this thesis. It is a former heating building that supplied energy to a mentioned complex. The attempt of the design was maximal purification from contemporary and purely functional interventions in order to support the historical footprint which is a fundamental factor for revitalization of the remaining parts of the area. The building is, in its own way, a manifestation of its surroundings. The object was cleansed to its visible structure made of bricks and wooden beam ceilings. This is refering to a time when these materials were understood as an essential costruction of every building, until they were replaced with structures from reinforced concrete and transparent facades with purely functional approach, which is visible in this new vision of Vlněna complex. Considering the administration aspect of the rest of the area, the building with its functional usage is trying to stimulate life and by that add space for social facilities. The object poetically named “the centre of regeneration“ includes many ways of relaxation which is an integral element to a monotone activities of administration buildings. The lower parts of the building contain a social function in the form of mini-brewery with beer hall/cellar, and restaurant in second floor. The other floors then offer regeneration, mental and physical, from massages to yoga practice. The result of this thesis is a revitalizational boost of the area. The object, in its function and form, is an opposite of new modern part of the complex. However, the object should not be unders
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