National Repository of Grey Literature 263 records found  1 - 10nextend  jump to record: Search took 0.02 seconds. 
The Assessment of the Local Water Supply Vohančice
Sovák, Zdeněk ; Svoboda, Pavel (referee) ; Kučera, Tomáš (advisor)
This bachelor thesis deals with the assessment of the municipal water supply system of Vohančice. It describes the current state of water supply, which is used to create a hydraulic model of the water supply network. The thesis focuses on the pressure and flow conditions of not only the current water distribution network but also the future planned extensions. Finally, options for measures for possible optimization of the water supply network are developed.
Directive on environmental liability with regard to the prevention and remedying of environmental damage and transposition in the Czech legal system
Jelínková, Petra ; Tichý, Luboš (advisor) ; Svoboda, Pavel (referee)
The subject of my master thesis is the EU directive 2004/35 on environmental responsibility, prevention and damage redress, its implementation into the legal order of the Czech Republic and the potential impact of undue transposition of the directive. The first part of my thesis deals with the harmonization need in this area and with the directive itself. Following a brief introduction of the directive, I'm presenting an overview of its basic institutes and their legal form. I'm also making an effort at identifying possible shortcomings of the directive. The basic institutes of the directive include: key principles, the environmental damage itself, operational activity, responsibility mechanisms, financial safeguards and the administrative procedure to impose a preventive or a remedial provisions. The second part of my thesis deals with the theoretical aspects of appropriate implementation, such as the interpretation of the directive, a timely adoption of the transposition provisions, proper projection of the content of the directive, due form of the transposition provisions, the application of EU norms, the equivalence and effectiveness imperative and the internal Czech rules for the implementation of EU norms that have been laid down by the governmental provision Nr. 1304 (methodological directions). The...
Omission of EU's member states leading to the liability for damage
Škarpichová, Jarmila ; Svoboda, Pavel (advisor) ; Král, Richard (referee)
OMISSION OF EU's MEMBER STATES LEADING TO THE LIABILITY FOR DAMAGE RESUMÉ This thesis deals with the responsibility of the member states of EU for damages caused by failure of member states. Both problems are solved in this work, as general requirements for liability relationship, as description of these failures modes with numerous references to case law of the European Court of Justice. Indeed, case law represented a huge range of sources for this thesis. To sum up the work into several points, we can start by making a breakthrough in the issue of liability in the European Union which Francovich case meant. This case established the rule that it is the responsability of member states to implement EU law properly and in time and provide protection to the rights that follow these standards. This rule was followed by other cases which are called "the first generation of cases liability" by many authors. Typical liability sentence: unlawful act (caused by the EU's institution), the damage suffered by the other party and the causal nexus, was subsequently supplemented by the Schöppenstedt criterion, which established the rule that during the process of adopting EU's legislation must be sufficiently serious breach of the law standards, which serves to protect the individual. The last unification of the...
Matrix effects in LC-MS analysis: occurrence, evaluation, and their elimination
Svoboda, Pavel ; Nováková, Lucie (advisor) ; Švec, František (referee) ; Havliš, Jan (referee)
Abstract Charles University, Faculty of Pharmacy in Hradec Králové Department of Analytical Chemistry Candidate: Mgr. Pavel Svoboda Supervisor: Assoc. Prof. PharmDr. Lucie Nováková, Ph.D. Advisor: RNDr. Hana Vlčková, Ph.D. Title of Doctoral Thesis: Matrix effects in LC-MS analysis: occurrence, evaluation, and their elimination The dissertation thesis deals with the issue of matrix effects in analysis using liquid chromatography coupled to mass spectrometry (LC-MS). LC-MS represents a well-established, widely used, and powerful tool in the field of qualitative and quantitative analysis of a wide range of different compounds. Despite all the advantages offered by LC-MS such as sensitivity, selectivity, and robustness, it suffers from a major drawback represented by matrix effects. This undesirable phenomenon affects important parameters of LC-MS method such as accuracy, precision, linearity, limit of detection, and limit of quantification. Therefore, an evaluation of these effects should be involved in validation of every single LC-MS method and their source should be eliminated. The assessment is generally performed by qualitative and quantitative approaches such as post-extraction addition, post-column infusion, and comparison of slopes of calibration curves. The matrix effects can be reduced or...
An impact of the recent economic crisis upon the control of mergers of competitors in the EU
Bartoš, Petr ; Šmejkal, Václav (advisor) ; Svoboda, Pavel (referee)
An impact of the recent economic crisis upon the control of mergers of competitors in the EU The purpose of this thesis is to analyse an impact of the recent economic crisis upon the control of mergers of competitors in the EU. It is established as an initial hypotheses that the economic crisis had considerable impact upon the EC merger control. The thesis is composed of six chapters, each of them dealing with different aspects of the above mentioned topic. Chapter One is introductory and defines basic terminology used in the thesis. The chapter is subdivided into two parts. Part One describes pre-crisis legal framework of EC merger control. Part Two deals with dominant pre-crisis theoretical approaches towards EC merger control. Chapter Two examines origin and development of the recent economic crisis, various regulatory responses to it, as well as the joint action of EU Member States towards dealing with consequences of the economic crisis. The chapter consists of seven parts, last one of them attempts to compare current situation in the EU with historical example of US antitrust enforcement during national crises. Chapter Three is focused on the impact of the recent economic crisis on EC merger control. It is subdivided into nine parts and provides an outline of the consistency on the principles...
Dominant position and its abuse in the Czech and European Community Law
Vavříček, Vladimír ; Svoboda, Pavel (referee) ; Šmejkal, Václav (referee)
This thesis addresses dominant position and its abuse in the Czech and in the European Community law, by the means of comparative method. Analyzes and comments on new, relevant courts practice and takes a closer look at reform of the competition law in the field of Art. 102 TFEU. For the sake of the global description of topic in question, the thesis briefly mentions concepts of economic position, economic dependency (significant market power) and their abuse and also presents concept of monopoly position and its abuse in antitrust law of the United States of America.
The legal framework of the development cooperation of the European Union
Trnka, Ondřej ; Svoboda, Pavel (advisor) ; Scheu, Harald Christian (referee)
The Legal Framework of the Development Cooperation of the European Union (The Legal Framework of EU Development Cooperation) The law of EU development cooperation has evolved dynamically in the recent years and its complex analysis exceeds the possibilities of this thesis. That is why solely two significant groups of legal rules are the object of this study. The first of these are the relevant provisions of the primary law (Part Two); the second then present legal norms which regulate EU development cooperation in its most characteristic form, i.e. as an activity consisting in a systematic providing of dedicated funds in order to support measures designed to achieve development goals (Part Three). Part One is devoted to necessary introductory comments. Part Two deals with the current changes in the primary law concerning the area of development cooperation. It is divided into two chapters. The first of these (Evolution of the relevant primary law provisions) summarizes the developments and importance of the key provisions of the founding treaties affecting development cooperation. A special attention is paid to the legal state before and after the entry into effect of the Lisbon Treaty, as right particular aspects of this transformation are analyzed in the second chapter of this part (Particular...
Development of UHPLC-MS/MS method for the determination of statins and their metabolites
Svoboda, Pavel ; Nováková, Lucie (advisor) ; Novák, Ondřej (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Analytical Chemistry Candidate: Pavel Svoboda Supervisor: Doc. PharmDr. Lucie Nováková, Ph.D. Title of Graduation Thesis: Development of UHPLC-MS/MS method for the determination of statins and their metabolites This graduation thesis deals with development of the method for the determination of statins and their metabolites by ultra-high performance liquid chromatography coupled to tandem mass spectrometry. First, the chromatographic conditions were optimized. Next, the parameters of mass spectrometer were optimized. And finally, repeatability, linearity and sensitivity of the method were assessed. Chromatographic column BEH C18 (50 x 2.1 mm, 1.7 µm) was used for the analysis. The choice of column was performed using UV spectrophotometric detector. The mobile phase of the gradient elution consisted of 0.1 mM ammonium acetate (A) and acetonitrile (B). The initial ratio of mobile phase A:B was set at 70:30. The optimization of the mass spectrometry parameters started with the selection of precursor ions using direct infusion. Thereafter, the ion source parameters of the mass spectrometer were optimized. The ion transitions were optimized after the selection of product ions. The optimization of ion transitions was...

National Repository of Grey Literature : 263 records found   1 - 10nextend  jump to record:
See also: similar author names
41 SVOBODA, Pavel
89 SVOBODA, Petr
1 Svoboda, P.
1 Svoboda, Patrik
10 Svoboda, Peter
89 Svoboda, Petr
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