National Repository of Grey Literature 11 records found  1 - 10next  jump to record: Search took 0.00 seconds. 
Architectural study of the sacral object Brno - Líšeň / second stage
Prokopová, Kateřina ; Žalmanová, Petra (referee) ; Šindlar, Jiljí (advisor)
The topic of the diploma thesis is the elaboration of the design of a new sacral building in Brno-Líšeň. The church building is complemented by a spiritual center with facilities. The church is to serve not only the contemporary Salesian community, but also to be open to a wider circle of believers. It is a slightly sloping plot in the middle of a panel building between the polyclinic building and the building of the Salesian Youth Center (= Salesko). Salesko is a non-profit organization whose mission is to accompany children and young people on their journey to adulthood and contribute to their physical, mental and spiritual development. The center builds on the preventive pedagogical system of Don Bosco, the founder of the Salesians. The idea is based on the main essence of the Salesians - home, family background, community. The design processes several interconnected operations into one complete unit with a common entrance atrium. The floor plan of the objects imitates the letter U, which means openness to the surrounding world, while also providing a certain background - safety. The buildings are single-storey, only the liturgical space itself, formed by a circular floor plan, forms a dominant dominant with a bell tower. Part of the design is the solution of parking spaces and free outdoor areas. From the urban point of view, emphasis is placed on walking accessibility, at the same time barrier-free access and use of the building is ensured.
Evaluation of Economy and Fundraising of Selected Non Profit Organization
Pospíchalová, Natálie ; Prokopová, Kateřina (referee) ; Lajtkepová, Eva (advisor)
This thesis focuses on economic development and fundraising activities in a choosen non profit organization called Vrátka. At the beginning, the goals and methods used in this bachelor's thesis are presented. Theoretical part of the thesis, shows the issue of non profit organizations which are described on the basis of selected literature. Theoretical part is the basis for the analytical part, where I performer the analysis of economic development and fundraising activities. The evaluation of the analytical part follows. From this evaluation come proposals for new financial resources for the non profit organization Vrátka.
New atelier of stage design at Kobližná Street in Brno
Prokopová, Kateřina ; Žáková, Dagmar (referee) ; Májek, Jan (advisor) ; Šuhajda, Karel (advisor)
The subject of the bachelor thesis is the elaboration of the pre-created architectural study into project documentation including architectural and technical details. The object is the reconstruction of the building in the city center of Brno - Central on the street Kobližná. The building is situated in the historical heart of the city and lies in a slightly sloping terrain. It is a 7th floor building with one underground floor. This is a design of a new atelier for students of stage design, especially workshops, laboratories, classrooms and studios of individual years. There is also a JAMU Rectorate, a public café and a shop of modeling needs. We think that the object is protected by the monument, which is why the mass and the original character of the building are preserved. The major changes will be in the layout, most partitions will be drained and the building will be broken down according to current needs and requirements.
Inflation Trends in the Czech Economy 1990-2006 (Documentational Survey)
PROKOPOVÁ, Kateřina
The aim of this bachelor work is to describe the summary documentation of inflation trends from the early 1990s up to present. The first part si presents the inflation primary information, its determination by the Czech National Bank, its stages and forms. There are the rate of inflation characterization and its konds at not least.The secon section is focused into the chronological developnemt of inflation in the Czech Republic divided itno five parts: the transtormation beginning (1990-1993), the trend of prices in 1994-1998, the perion 1999-2001, the inflation progress in 2002-2005 and the first three months of 2006.
The role of erbB-2 oncogene in the biology of cancer stem-like cells
Prokopová, Kateřina ; Neužil, Jiří (advisor) ; Anděra, Ladislav (referee)
Recent studies indicate the existence of a subpopulation of cells within tumours with stem cell-like characteristics. These "cancer stem-like cells" (CSCs) are relatively resistant to established therapies, usually targeting differentiated and fast proliferating cells. Therefore, CSCs may be a reason for the relapse of neoplastic diseases. CSCs can be characterised by a specific gene expression profile and deregulated signalling pathways. Of these, upregulation of the erbB-2 (HER2) receptor, a hallmark of ~25-30% breast cancer patients, is related to dismal prognosis, elevated proliferation potential and resistance to chemotherapy. Recent evidence has suggested that upregulation of erbB-2 leads to increase in the pool of CSCs. In our study we used mammospheres, cells grown in the absence of serum, an in vitro model of breast CSCs, which were prepared by "weaning" breast cancer MCF7 cells to a special medium. These cells were CD44high and showed increased expression of ABCG-2, Sox-2, Vimentin as well as high levels of erbB-2. Next, we prepared a stable line of MCF7 cells with low levels of erbB-2 by shRNA. ErbB-2low cells were characterised for expression of set of CSCs markers and tested for tumour forming efficacy in nude mice using ultrasound imaging. Keywords Cancer stem-like cells, erbB-2,...
Evaluation of Economy and Fundraising of Selected Non Profit Organization
Pospíchalová, Natálie ; Prokopová, Kateřina (referee) ; Lajtkepová, Eva (advisor)
This thesis focuses on economic development and fundraising activities in a choosen non profit organization called Vrátka. At the beginning, the goals and methods used in this bachelor's thesis are presented. Theoretical part of the thesis, shows the issue of non profit organizations which are described on the basis of selected literature. Theoretical part is the basis for the analytical part, where I performer the analysis of economic development and fundraising activities. The evaluation of the analytical part follows. From this evaluation come proposals for new financial resources for the non profit organization Vrátka.
Architectural study of the sacral object Brno - Líšeň / second stage
Prokopová, Kateřina ; Žalmanová, Petra (referee) ; Šindlar, Jiljí (advisor)
The topic of the diploma thesis is the elaboration of the design of a new sacral building in Brno-Líšeň. The church building is complemented by a spiritual center with facilities. The church is to serve not only the contemporary Salesian community, but also to be open to a wider circle of believers. It is a slightly sloping plot in the middle of a panel building between the polyclinic building and the building of the Salesian Youth Center (= Salesko). Salesko is a non-profit organization whose mission is to accompany children and young people on their journey to adulthood and contribute to their physical, mental and spiritual development. The center builds on the preventive pedagogical system of Don Bosco, the founder of the Salesians. The idea is based on the main essence of the Salesians - home, family background, community. The design processes several interconnected operations into one complete unit with a common entrance atrium. The floor plan of the objects imitates the letter U, which means openness to the surrounding world, while also providing a certain background - safety. The buildings are single-storey, only the liturgical space itself, formed by a circular floor plan, forms a dominant dominant with a bell tower. Part of the design is the solution of parking spaces and free outdoor areas. From the urban point of view, emphasis is placed on walking accessibility, at the same time barrier-free access and use of the building is ensured.
New atelier of stage design at Kobližná Street in Brno
Prokopová, Kateřina ; Žáková, Dagmar (referee) ; Májek, Jan (advisor) ; Šuhajda, Karel (advisor)
The subject of the bachelor thesis is the elaboration of the pre-created architectural study into project documentation including architectural and technical details. The object is the reconstruction of the building in the city center of Brno - Central on the street Kobližná. The building is situated in the historical heart of the city and lies in a slightly sloping terrain. It is a 7th floor building with one underground floor. This is a design of a new atelier for students of stage design, especially workshops, laboratories, classrooms and studios of individual years. There is also a JAMU Rectorate, a public café and a shop of modeling needs. We think that the object is protected by the monument, which is why the mass and the original character of the building are preserved. The major changes will be in the layout, most partitions will be drained and the building will be broken down according to current needs and requirements.
The role of erbB-2 oncogene in the biology of cancer stem-like cells
Prokopová, Kateřina ; Neužil, Jiří (advisor) ; Anděra, Ladislav (referee)
Recent studies indicate the existence of a subpopulation of cells within tumours with stem cell-like characteristics. These "cancer stem-like cells" (CSCs) are relatively resistant to established therapies, usually targeting differentiated and fast proliferating cells. Therefore, CSCs may be a reason for the relapse of neoplastic diseases. CSCs can be characterised by a specific gene expression profile and deregulated signalling pathways. Of these, upregulation of the erbB-2 (HER2) receptor, a hallmark of ~25-30% breast cancer patients, is related to dismal prognosis, elevated proliferation potential and resistance to chemotherapy. Recent evidence has suggested that upregulation of erbB-2 leads to increase in the pool of CSCs. In our study we used mammospheres, cells grown in the absence of serum, an in vitro model of breast CSCs, which were prepared by "weaning" breast cancer MCF7 cells to a special medium. These cells were CD44high and showed increased expression of ABCG-2, Sox-2, Vimentin as well as high levels of erbB-2. Next, we prepared a stable line of MCF7 cells with low levels of erbB-2 by shRNA. ErbB-2low cells were characterised for expression of set of CSCs markers and tested for tumour forming efficacy in nude mice using ultrasound imaging. Keywords Cancer stem-like cells, erbB-2,...

National Repository of Grey Literature : 11 records found   1 - 10next  jump to record:
See also: similar author names
9 PROKOPOVÁ, Kateřina
4 PROKOPOVÁ, Klára
1 Prokopová, Kamila
4 Prokopová, Klára
2 Prokopová, Kristýna
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