National Repository of Grey Literature 15 records found  1 - 10next  jump to record: Search took 0.00 seconds. 
Study of DNA-doxorubicine interaction by electrochemical methods on nanostructured electrodes
Přibyl, Jakub ; Fohlerová, Zdenka (referee) ; Kynclová, Hana (advisor)
Cancer diseases are one of the leading causes of mortality worldwide, for this reason, great attention anticancer drugs. Doxorubicin falls into the category of the most widely used cancer drugs. The method of electrochemical impedance spectroscopy were investigated properties of golds electrodes without deposit nanoparticles and electrodes with deposit gold nanoparticles. Using voltammetric measurements we detected doxorubicin and investigated the interaction of doxorubicin with oligonucleotides on gold electrodes without nanoparticles and electrodes modified with gold nanoparticles.
Electrochemical Characterization of Nanostructured Surfaces Modified by Substancies with Thiol Bound
Urbánková, Kateřina ; Kynclová, Hana (referee) ; Hrdý, Radim (advisor)
This master thesis deals with nanotechnology, nanoparticles and nanostructured surfaces, electrochemical methods, especially voltammetry, cyclic voltammetry, electrochemical impedance spectroscopy and contact angle measurement. One part is focused on electrodes primarily nanostructured and modified by substancies with thiol bound. Tutorial for preparation of gold nanostructured electrods is introduced in practical section including SEM photos of electrode surface. Nanostructured and bare gold electrodes were modified by 11-mercaptoundecanoic acid, streptavidin, glycine and biotin and measured by cyclic voltammetry, electrochemical impedance spectroscopy and contact angle.
Production and characterization of nanoporous alumina membranes
Šimik, Milan ; Márik, Marian (referee) ; Kynclová, Hana (advisor)
The Bachelor thesis mostly deals with manufacturing of membranes with anodic oxidation of aluminium in different conditions. In theoretical part are studied processes leading to creating of porous alumina and methods of measuring permeability of membranes. Practical part is aimed on manufacturing porous alumina with different conditions, which are afterwards suffused into form and diffuse characterized. Measured parametres are interpreted and compared with each other.
Study of intercalation and covalent bond of doxorubicin into deoxyribonucleic acid using voltammetry and impedance spectroscopy
Kynclová, Hana ; Trnková, Libuše (referee) ; Hubálek, Jaromír (advisor)
Doxorubicine is one of the most used anticancer medicaments nowadays. Improvement of Electrochemical Impedance Spectroscopy and cyclic voltammetry was investigated influence of doxorubicine to sensitive cells and resistibility cells.
Characterization of nanostructured electrodes for electrochemical biosensors
Kynclová, Hana ; Drbohlavová, Jana (referee) ; Hubálek, Jaromír (advisor)
Nowadays it is attached to a major effort to study applications of nanoparticles in biosensors technology. We studied the effect of gold nanoparticles on the surface of the electrodes by Electrochemical Impedance Spectroscopy method and Cyclic Voltammetry. For impedance measurements was proposed substitute electrical model and cyclic voltammetry method was used to determine the electroactive surface of electrodes.
Electrochemical sensor for ascorbic acid detection
Hlavička, Michal ; Kynclová, Hana (referee) ; Majzlíková, Petra (advisor)
This work deals with electrochemical detection of ascorbic acid using screen-printed three-electrode sensors. The work is divided into three parts, where the first describes the theory of thick-film technology, including the types and compositions of the pastes, fabrication and firing. The second part deals with the methods, measurement principles and the electrochemical detection of ascorbic acid. Experiments were done using screen-printed carbon electrodes in a solution of phosphate buffer and ascorbic acid. In conclusion the results are evaluated.
Nanopatterned alumina-based materials for electrochemical sensors and biosensors
Kynclová, Hana ; Hynek, David (referee) ; Trnková, Libuše (referee) ; Prášek, Jan (advisor)
The doctoral thesis is focused on basic research and development of nanostructured surfaces prepared using anodic alumina material. Various types of gold nanostructured surfaces and nanoporous aluminum membranes for electrochemical sensors and biosensors were prepared using the anodic oxidation method. Nanostructured surfaces were prepared by electrochemical anodization of aluminum material to form hexagonally arranged nanopores. Gold was then deposited into the nanoporous masks by electrochemical reduction from potassium dicyanoaurate solution using a pulse deposition method. The prepared nanostructured gold surfaces were electrochemically characterized by electrochemical impedance spectroscopy and voltammetry. Temperature stability and the effect of annealing on their electrochemical behavior at atmospheric pressure as well as in the vacuum were investigated. Then, gold nanostructures of various dimensions were prepared and the influence of their shape and dimensions on the electrochemical behavior was studied. Nanostructured surfaces were also modified with 11–mercaptoundecanoic acid, and the effect of this modification on the electrochemical results was studied. In the last part of the work, nanoporous aluminum membranes were prepared, and their permeability was studied.
Nanopatterned alumina-based materials for electrochemical sensors and biosensors
Kynclová, Hana ; Hynek, David (referee) ; Trnková, Libuše (referee) ; Prášek, Jan (advisor)
The doctoral thesis is focused on basic research and development of nanostructured surfaces prepared using anodic alumina material. Various types of gold nanostructured surfaces and nanoporous aluminum membranes for electrochemical sensors and biosensors were prepared using the anodic oxidation method. Nanostructured surfaces were prepared by electrochemical anodization of aluminum material to form hexagonally arranged nanopores. Gold was then deposited into the nanoporous masks by electrochemical reduction from potassium dicyanoaurate solution using a pulse deposition method. The prepared nanostructured gold surfaces were electrochemically characterized by electrochemical impedance spectroscopy and voltammetry. Temperature stability and the effect of annealing on their electrochemical behavior at atmospheric pressure as well as in the vacuum were investigated. Then, gold nanostructures of various dimensions were prepared and the influence of their shape and dimensions on the electrochemical behavior was studied. Nanostructured surfaces were also modified with 11–mercaptoundecanoic acid, and the effect of this modification on the electrochemical results was studied. In the last part of the work, nanoporous aluminum membranes were prepared, and their permeability was studied.
Study of Electrochemical Behaviour of Gold Nanostructured Surfaces
Kynclová, Hana
Recently, nanostructured surfaces have been extensively studied due to their possibility to use them in construction of electrochemical sensors and biosensors. We have prepared tungsten working electrode modified with gold nanocolumns via galvanic deposition of gold ions through anodic alumina nanoporous template. This nanostructured surface was subsequently electrochemically characterized by cyclic voltammetry using K3[Fe(CN)6]/K4[Fe(CN)6] probe and compared with the results measured on a flat gold electrode. The electroactive areas for both types of electrodes were evaluated and compared. It was found that the nanostructured area affected the response on lower scan rates (up to 25 mV.s-1) and increased the response at higher scan rates (higher than 50 mV.s-1) which is probably related to penetration of electrolyte solution among nanocolumns. Nevertheless, this fact can help in speed of analyses of huge amount of samples.
Production and characterization of nanoporous alumina membranes
Šimik, Milan ; Márik, Marian (referee) ; Kynclová, Hana (advisor)
The Bachelor thesis mostly deals with manufacturing of membranes with anodic oxidation of aluminium in different conditions. In theoretical part are studied processes leading to creating of porous alumina and methods of measuring permeability of membranes. Practical part is aimed on manufacturing porous alumina with different conditions, which are afterwards suffused into form and diffuse characterized. Measured parametres are interpreted and compared with each other.

National Repository of Grey Literature : 15 records found   1 - 10next  jump to record:
See also: similar author names
1 Kynclová, H.
1 Kynclová, Hedvika
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