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Spiritual needs in hospice care
HOLÁ, Klára
The work deals with spiritual needs of clients of home hospice care. The theoretical part is about palliative care and spiritual needs. The empirical part is made up of quality research that analyzes the understanding of home hospice clients of the concept of spiritual needs based on semi-structured interviews with them and it finds out the importance of selected spiritual needs for these clients as well.
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Phonetics in the teaching of German as a foreign language
Holá, Klára ; Berglová, Eva (advisor) ; Machač, Pavel (referee)
This thesis explains the role of phonetics in the teaching of German as a foreign language. The beginning examines the present state - here I try to target in particular the Common European Framework of Reference for Languages and its parts that have to do with phonetics. Next, I explain certain terms with which I work with in most of the thesis. The next chapter concentrates on the role that phonetics play in the teaching of foreign languages. In the practical part of this work I deal with the differences of Czech and German pronunciation. The changes I discovered by comparing both languages became the fundamentals of the phonetic analysis of twenty recordings that obtained a total of 1480 analyzed documents, from which I determined that Czech students have the hardest time pronouncing the following German sounds , , , and . The task of the next analysis was to determine how the pronunciations of these problematic sounds are processed in the following text books: Delfin, Planet and Tangram. The best text book was Tangram, then Delfin and the worst was Planet. Unfortunately, none of the text books emphasize pronunciation and exercising it to a sufficient degree.
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Molecular dynamics of proteins interacting with substrate or ligand: mitochondrial processing peptidase and FixL oxygen sensor
Dvořáková Holá, Klára ; Janata, Jiří (advisor) ; Váchová, Libuše (referee) ; Branny, Pavel (referee)
I I Ovenvrew I I I II I I I I I I I I I The presenteddoctoralthesis includesfive publishedscientificarticlesand one manuscriptpreparedfor submission.All describestudieson threeproteinmodels.The four papersnumbered(1)- (4)inthelistofpublications,sharea commonobjectivee.i.observingand describingfunctionalproteindynamicsandconformationchangeinducedby ligandor substrate binding,andrepresentthemainresultofmyPhDwork. Thepapers(1)and(4)offerresultsof a projectfrommyhomelaboratoryattheInstitute ofMicrobiologyAS CR, LaboratoryforBiologyofSecondaryMetabolism,underthesupervisionof JiřÍ Janata, PhD. The projectis focusedon the protein-proteindynamicsinteractionof mitochondrialprocessingpeptidase(MPP) fromSaccharomycescerevisiaewithits preproteins substrates. The papers(2)and(3)describeresultsof a project,inwhichI haveparticipatedduring myMarieCuriefellowshipattheEcolePolytechnique(PalaiseauCedex,France),Laboratoryfor OpticsandBiosciences,in2004.Theprojectconcernsresearchon proteinstructuraldynamicsof theheme-basedoxygensensorFixLfromBradyrhizobiumjaponicum,inwhichoxygenbindingto the heme sensor domain inducesconformationchange,which regulatesthe activityof neighboringkinasedomain. ln bothprojects,analogyin methodicalapproach,i.e.seriesof molecularbiologyand...
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Crisis of the Life-World
Holá, Klára ; Pelcová, Naděžda (advisor) ; Hogenová, Anna (referee) ; Pauza, Miroslav (referee)
Krize přirozeného světa The crisis of the Life-world PhDr. Klára Holá This doctoral thesis called The crisis of the Life-world is an interdisciplinary theoretical treatise on a problem of the crisis in connection with the Life-world, the main phenomenological issue. The crisis is related to the Life-world itself. The thesis tries to explain the problem of the crisis as a timeless concept ontologically related to a human being, as well as an ethical issue accompanying the development of the modern society. The aim of the thesis is to define the crisis of the Life-world, to describe its symptoms in the various areas, and to outline some possible solutions. To achieve the aim I have divided the conception of the crisis into two meanings which are related to each other: the ontological crisis and the ethical crisis. My hypothesis has proved the ontological crisis unavoidable, as it springs from the ambivalent position of the human being whereas we can balance the ethical aspects in various ways. I have used the comparative and phenomenological method as well as the phenomenological-hermeneutic methods of the text-interpretation. I also used the specific phenomenological method of transcendental epoché. Therefore, I have preferred the interdisciplinary access to this problem. The access can reveal in the...
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Molecular dynamics of proteins interacting with substrate or ligand: mitochondrial processing peptidase and FixL oxygen sensor
Dvořáková Holá, Klára ; Janata, Jiří (advisor) ; Váchová, Libuše (referee) ; Branny, Pavel (referee)
I I Ovenvrew I I I II I I I I I I I I I The presenteddoctoralthesis includesfive publishedscientificarticlesand one manuscriptpreparedfor submission.All describestudieson threeproteinmodels.The four papersnumbered(1)- (4)inthelistofpublications,sharea commonobjectivee.i.observingand describingfunctionalproteindynamicsandconformationchangeinducedby ligandor substrate binding,andrepresentthemainresultofmyPhDwork. Thepapers(1)and(4)offerresultsof a projectfrommyhomelaboratoryattheInstitute ofMicrobiologyAS CR, LaboratoryforBiologyofSecondaryMetabolism,underthesupervisionof JiřÍ Janata, PhD. The projectis focusedon the protein-proteindynamicsinteractionof mitochondrialprocessingpeptidase(MPP) fromSaccharomycescerevisiaewithits preproteins substrates. The papers(2)and(3)describeresultsof a project,inwhichI haveparticipatedduring myMarieCuriefellowshipattheEcolePolytechnique(PalaiseauCedex,France),Laboratoryfor OpticsandBiosciences,in2004.Theprojectconcernsresearchon proteinstructuraldynamicsof theheme-basedoxygensensorFixLfromBradyrhizobiumjaponicum,inwhichoxygenbindingto the heme sensor domain inducesconformationchange,which regulatesthe activityof neighboringkinasedomain. ln bothprojects,analogyin methodicalapproach,i.e.seriesof molecularbiologyand...
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Crisis of the Life-World
Holá, Klára ; Pelcová, Naděžda (advisor) ; Hogenová, Anna (referee) ; Pauza, Miroslav (referee)
Krize přirozeného světa The crisis of the Life-world PhDr. Klára Holá This doctoral thesis called The crisis of the Life-world is an interdisciplinary theoretical treatise on a problem of the crisis in connection with the Life-world, the main phenomenological issue. The crisis is related to the Life-world itself. The thesis tries to explain the problem of the crisis as a timeless concept ontologically related to a human being, as well as an ethical issue accompanying the development of the modern society. The aim of the thesis is to define the crisis of the Life-world, to describe its symptoms in the various areas, and to outline some possible solutions. To achieve the aim I have divided the conception of the crisis into two meanings which are related to each other: the ontological crisis and the ethical crisis. My hypothesis has proved the ontological crisis unavoidable, as it springs from the ambivalent position of the human being whereas we can balance the ethical aspects in various ways. I have used the comparative and phenomenological method as well as the phenomenological-hermeneutic methods of the text-interpretation. I also used the specific phenomenological method of transcendental epoché. Therefore, I have preferred the interdisciplinary access to this problem. The access can reveal in the...
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Development of educational PC software for visually impaired children
Holá, Klára ; Kučera, Miloš (referee) ; Šumníková, Pavlína (advisor)
The diploma work is focused on development of educational PC software dedicated to visually impaired children. It is intended for junior school-aged children with visual abilities in category of middle and high level of low vision and also for children with disorders of binocular vision. The intention of this sotware is education of visually impaired children especially in domain of knowledge about the world of animals. It also helps children to reeducate their vision abilities.
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The Problem of the Natural World in Phenomenology Reflection
Holá, Klára ; Pelcová, Naděžda (advisor) ; Hogenová, Anna (referee)
The thesis called The Problems Of The Natural World In Phenomenology Reflection is supposed to be an attempt of the interdisciplinary social sciences and philosophy conception in terms of these units: everyday life, intersubjectivity, language, world complex, home and freedom. It arises from the comparison of the German phenomenology's conceptions of Edmund Husserl and Martin Heidegger and the Czech philosopher Jan Patočka. It is focused on how a subject reflects his own world, enjoys it and creates it in conjunction with others. It is also concerned with the issue of the education, which helps to form of the enjoyment with the natural world, developing world experience and skills and also forms freedom and responsible attitude towards shared natural world.
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Phonetics in the teaching of German as a foreign language
Holá, Klára ; Machač, Pavel (referee) ; Berglová, Eva (advisor)
This thesis explains the role of phonetics in the teaching of German as a foreign language. The beginning examines the present state - here I try to target in particular the Common European Framework of Reference for Languages and its parts that have to do with phonetics. Next, I explain certain terms with which I work with in most of the thesis. The next chapter concentrates on the role that phonetics play in the teaching of foreign languages. In the practical part of this work I deal with the differences of Czech and German pronunciation. The changes I discovered by comparing both languages became the fundamentals of the phonetic analysis of twenty recordings that obtained a total of 1480 analyzed documents, from which I determined that Czech students have the hardest time pronouncing the following German sounds , , , and . The task of the next analysis was to determine how the pronunciations of these problematic sounds are processed in the following text books: Delfin, Planet and Tangram. The best text book was Tangram, then Delfin and the worst was Planet. Unfortunately, none of the text books emphasize pronunciation and exercising it to a sufficient degree.
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