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Learning how to Learn in Inclusive Secondary Education
Vermeulen, Dayan Egberdina Wilhelmina ; Strnadová, Iva (advisor) ; Černá, Marie (referee)
The topic of this dissertation is "Learning how to learn in inclusive secondary education." The central subject of this dissertation is the facilitation of processes in which students develop awareness of their own learning-styles and educational needs. In my opinion, awareness of learning-styles and awareness of personal educational needs by students and teachers should lead to educational programmes, environments, settings and facilitations that promote more effective and joyful learning for all. In their actual practices of educational change and development, schools meet several problems concerning the quality of education that produce questions for research. To find solutions for some of these questions we started a participative action research project. The action research area for this project was Inclusive Secondary Education and the coresearchers in the action-research process were teachers as well as students. All five schools involved in this research program are inclusive mainstream schools in the sense that children with visual or communication handicaps, physically and mentally handicaps (limit TIQ= 40) as well as students with behavioral problems and students without handicap are welcome. Powered by TCPDF (www.tcpdf.org)
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Reflective practices in Teaching
Chen, Ye ; Šiška, Jan (advisor) ; Černá, Marie (referee)
The aim of this research is to find out if reflective practices exist in Czech schools and whether teachers arc aware of it. Besides, tcachcrs' opinions on reflection as well as conditions that may influence reflection arc examined. For this purpose, a small-scalc questionnaire-based study is earned out with tcachcrs in mainstream and spécial schools. Mixed-methods approach is adopted to collect data from questionnaire, observation and interview, which is then analysed by means of triangulation. Powered by TCPDF (www.tcpdf.org)
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Attitudes of Young Adolescents toward their Peers with Intellectual Disabilities
Kuo, Hui-Wen ; Černá, Marie (advisor) ; Strnadová, Iva (referee)
This study explores the attitudes of young adolescents towards their peers with intellectual disabilities in Prague, Czech Republic. A total of 253 young adolescents participated in this study, with 134 male and 119 female in 7th, 8th, and 9th grade. The attitudes of the young adolescents were surveyed by making use of the attitude questionnaire designed by the researcher. The roles of previous contact, gender and grade were examined. Results indicated that young adolescents were generally positive toward their peers with intellectual disabilities. Young adolescents who had previous contact with people with intellectual disabilities are more positive than those who did not. Female were more positive than male. 9th graders who participated were not more positive than those in 7th graders. Possibilities and suggestions for future researches and education were suggested. Powered by TCPDF (www.tcpdf.org)
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HLA Class II Antigens as a Main Predisposition Factor for Autoimmune Diabetes Mellitus.
Zikmundová, Veronika ; Holáň, Vladimír (referee) ; Černá, Marie (advisor)
Autoimmune diabetes (type 1 diabetes, T1D) is a multifactorial disease, where the immune system reacts against pancreatic β-cells of Langerhans islets. Their progressive destruction causes insufficient function of insulin for the organism and production of autoantibodies. These antibodies serve as markers of autoimmune insulitis even before the manifestation of the disease. T1D is triggered by environmental factors in genetically predisposed individuals. Genetic susceptibility mainly relates to HLA genes, which cause about 50 % of familiar occurences. The most risk factors are HLA-DR3, HLA-DR4 and HLA-DQ8 antigens. Their aminoacidic structure determines which peptides would bind to individual antigens and how firmly. However, these antigens do not function separately. They are in tight linkage disequilibrium and it is therefore not possible to determine the individual function of each of them in autoimmune process unambiguously. Environmental factors can have protective effect on individuals (e.g. vitamin D), but they can have predisposition effect for autoimmunity as well. The most discussed trigger mechanisms are viral infections (specifically Coxsackie B4 virus) and premature exposure of newborns to cow-milk.
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Prognosis and diagnostics in acute myeloid leukemia
Jiráková Trnková, Zuzana ; Jíra, Milan (advisor) ; Černá, Marie (referee) ; Špíšek, Radek (referee)
The main aim of the dissertation was in patients with acute myeloid leukemia to investigate the impact of favorable prognostic chromosomal aberrations and increased expression of a family of multiple drug resistance genes to achieve a complete remission and overall survival, and identify the potential prognostic factors. Experiments were focused on the introduction of routine diagnostics of two prognostically favorable fusion genes, AML1/ETO and CBFbeta/MYH11 and multiple drug resistance gene MDR1. This testing was performed by reverse transcription, PCR and subsequent electrophoretic analysis of its products.
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Molecular aspects of genetic predisposition to type 2 diabetes mellitus and its monogenic forms
Pintérová, Daniela ; Černá, Marie (advisor) ; Bendlová, Běla (referee) ; Hubáček, Jaroslav (referee)
The aim of this work was to study some molecular aspects of genetic predisposition to T2DM and its monogenic forms. We searched for correlations of genotypes with many clinical and laboratory markers and tried to evaluate their significance. The consequences for possible changes in the treatment some particular patients were under discussion. Especially for those suffering from monogenic forms we were able to reach better compensation of DM, or at latest the same compensation for more acceptable therapy. We studied the associations of chosen candidate genes, PPAR, NF-B, its inhibitor IB, known polymorphisms and T2DM including diabetic complications. We used the association study approach to find out if there is any association between available genetic variants among our patients and T2DM with its phenotypic abnormalities (changed levels of total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides, further the presence of diabetic complications).
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Comprehensive care for children with multiple disabilities (combination of mental and physical disabilities)
Zikl, Pavel ; Titzl, Boris (advisor) ; Stejskal, Bohumil (referee) ; Černá, Marie (referee)
The main topic of my work is comprehensive care for children with multiple disabilities (combination of mental and physical disabilities). The theoreticmethodical part is aimed at used terminology, estimated number of such pupils in our schools and at comprehensive care/rehabilitation. Main stress is put on medical rehabilitation and the possibility of using it at schools (methods of medical rehabilitation used at schools, positioning). In the second part results of research work connected with education and comprehensive care for children with mental and multiple disabilities are presented. They are two separate pieces of research connected together with different methodology used in each of them. The first one is a quantitative research (description and analysis of education of pupils with mental and multiple disabilities integrated in common schools). The second one is a qualitative research (analysis and comparison of education of children with multiple disabilities in special and common schools). The summary and a discussion are at the end of the work.
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Quality of life of young adults with mental retardation
Kollerová, Lenka ; Strnadová, Iva (advisor) ; Černá, Marie (referee)
The thesis focuses on quality of life of persons with intellectual disability during the period of young adulthood. In theoretical part I deal with the topics "who is a young adult with intellectual disability" and "what issues does he/she face in this life stage". I engage in contemporary concepts and approaches to quality of life and choose some of them as crucial for my work. The primary focus is given to one of the eight domains of quality of life (according Schalock's concept) - self-determination. Empirical part deals with qualitative study that was carried out in the form of a semistructured interview with people with intellectual disability and that is focused on two major areas. The first area refers to a subjective satisfaction with a fulfilment of person's most important targets, the second area concerns with decision making and autonomy (two indicators of self-determination). The work brings information about notions of the independent (self-managed) life, the work-life and the partnership of persons with intellectual disability. My aim was to notice a subjective sensation and gain deeper insight into the individual experience of the respondents. 2
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