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Morphology of the mandible with regard to the demographic structure of the early medieval burial area Mikulčice
Thon, Tomáš ; Bejdová, Šárka (advisor) ; Velemínský, Petr (referee)
This Master's thesis focuses on the influence of socioeconomic status on the morphology of the mandible of individuals from the early medieval burial area in Mikulčice. This hillfort was an important center of power of the Great Moravian Empire with a stratified society. This work compares 2 different approaches on how to divide the inhabitants. The first of them is the division of individuals according to the location of graves into individuals from the castle, sub-castle, and hinterland. The second approach is the division of individuals according to the richness of grave equipment into individuals with rich and poor grave equipment. A different social status is associated mainly with different diets. Therefore, the attachments of the masticatory muscles are the most affected areas. A total of 132 individuals (59 males and 73 females) were analyzed. The material was evaluated by methods of geometric morphometrics. The used methods were CDP DCA, GPA, two-sample t-test, PCA, MANOVA, and SVM. Sexual dimorphism was observed in all sub-groups of the Mikulčice population. Men have larger mandibles with rami wider apart. The biggest differences are between individuals from the castle, the smallest between individuals with rich grave equipment. The distribution of individuals based on the location of...
Reliability of Klales et al. (2012) method for sex assessment from hip bone based on CT imaging
Firlová, Radka ; Brůžek, Jaroslav (advisor) ; Galeta, Patrik (referee)
The study is primarily focused on testing of the method which assesses sex from pubis. This method was originally proposed by Phenice (1969). Klales et al. (2012) modified this method in their study. They suggested to improve of the Phenice (1969) technique by extending the evaluation scale of three morphological traits from two values - present / absent to five development stage. Our study assumes that the success of Phenice (1969) method is related to the degree of sexual dimorphism of evaluated population. So the extension of evaluation scale will not lead to increased accuracy and will occur to decrease relibility of the method also. Intraobserver error was evaluated for Phenice (1969) a Klales et al. (2012) methods on the sample of isolated pelvic bones from Department of anthropology and human genetics of Charles university in Praque in first time. After we evaluated the whole sample, which consist of 200 three-dimensional models of pelvic bones. These models were segmented from CT images of adult individuals from contemporary French population. This sample was statistically evaluated by Cohen kappa, accuracy, senzitivity and specificity using confusion matrix and relationship between specificita and senzitivity was tested by ROC curves and area under curve (AUC). Results show that Phenice...
Intersexual differences of adiposity markers in contemporary Czech children aged 11 - 15 years
Auxtová, Martina ; Sedlak, Petr (advisor) ; Zamrazilová, Hana (referee)
Thesis is focused on the analysis of intersexual differences in adiposity markers within urban population of Czech children from 11,00 to 15,99 years. This age range encompasses puberty which is one of the critical periods for the possible development of overweight and obesity. The sample PRAHA 2013 consists of 356 girls and 353 boys which were surveyed for basic anthropometric indicators - body height, body weight, BMI, mid- upper arm circumference and the thickness of four skinfolds. Intersexual differences discovered in measured parameters show statistical significance (p<0,01 resp. p<0,001) and it corresponds with the characteristic changes of pubertal development in both of genders. Testing file PRAHA 2013 against reference standards and its comparison with the results of the last Czechoslovak spartakiade in 1985 points to positive secular trend of increasing body height. However increase in weight parametres is still continuing. Probands from the year 2013 reach higher body weight values, BMI and skinfold thickness in comparison with children of the same age in 1985, 1991 resp. 2001. Significant differences were found out in the most of age categories in both of genders. Keywords: adiposity tissue, subcutaneous fat, skinfolds, body fat distribution, sexual dimorphism, obesity, secular trend
Morphological variation of Cameroonian sunbirds
Bovšková, Denisa ; Hořák, David (advisor) ; Chmelová, Eliška (referee)
5 Abstract Morphological traits give information about the adaptations of the studied species, the resources, which it uses, and they can generally tell us about the use of ecological space. Intraspecific morphological variability reflects various adaptations of local populations thus variability reflect different way of life. The subject of this thesis is an ecologically interesting group of specialized tropical songbirds - Sunbirds (Nectarinidae). The taxon exhibits number of adaptations to specific food collecting a combination of nectarivory and insect hunting. I focused here on the intraspecific variability of three species (Cyanomitra oritis, Cinnyris reichenowi and C. bouwieri) living in different habitats in Cameroon. The aim of this work was to find out in what morphological characters are this species sexually dimorphic. Furthermore, if their populations living in remote locations differ? Finally, if all studied species show similar trend of intraspecific variability of the traits, which could have common ecological causes. The following traits were measured: wing and tail feather length, beak dimensions, total body weight and other characters. The analysis is based on field data collected between 2003 and 2015 and museum collections. Overall, we collect information about ca. 1200 individuals for...
Sexual dimorphism in tibial loading during human locomotion
Dvořáková, Barbora ; Hora, Martin (advisor) ; Friedl, Lukáš (referee)
Locomotion is one of the most important qualities of man and has always been associated with survival, foraging ans subsistence. During the course of evolution, men and women developed some form of gender specialization which resulted in different level of mobility between the sexes. Throughout history, the types of subsistence have changed and the degree of sedentism has increased. However, despite all the changes in subsistence, gender specialization and bone robusticity sexual dimorphism in the robusticity of the lower limb bones remained surprisingly stable. Is it possible that women load lower limb bones differenty than men (e.i. due to different body proportions)? The aim of this work is to determine wheter there is sexual dimorphism between the sexes of the recent living population in the cross-sectional properties of the tibia and in the load on the tibia during running. In this work we used images of the tibia from magnetic resonance imaging and kinematic and kinetic data during the run of 20 probands. By using musculoskeletal modeling we estimated the bending moment acting at 50 % of the tibial length as well as the angle of action of this moment. After adjusting for size, no significant difference was found in the results of cross-sectional geometry of the bone in any of the monitored...
Shape variability of proximal and distal human tibia.
Brzobohatá, Hana
The aim of this study was to detect and describe the trends in shape variability of proximal and distal human tibia related to sex, age, social status and time period. The variability of its shape and form was analysed first in an early medieval sample, then in two modern populations, an early 20th century sample and the contemporary Czech population. Finally, data from the whole studied time span were analysed. The initial raw data were acquired by optical scanning and computed tomography (CT) scanning of the lower limbs; the three-dimensional bone surfaces of the contemporary tibias were segmented from the clinical CT scan sequences. Geometric morphometrics and multivariate statistical methods were applied to study the variations in shape and form quantitatively. Proximal and distal tibias were evaluated independently, and the potential influence of sex, age at death and time period were investigated. In the early medieval population, we also explored the relationship between tibial morphology and presumed social status derived from the respective grave location within the settlement. Because traditional morphometric analysis revealed statistically significant sex differences in the parameters of both tibial extremities (e.g., Steyn and Işcan, 1997; Šlaus et al., 2013), we thus assumed the...
Changes of the facial skeleton in Central Europe during the last 1200 years
Bejdová, Šárka
The objective of the Dissertation was to describe, quantify and interpret to which degree the shape and size of the facial skeleton of people living in the territory of today's Czech Republic in the period from the Early Middle Ages to the present day, i.e. in the course of the approx. last 1200 years, have changed. In this time period, morphological differences between populations, changes in the sexual dimorphism, modularity and allometry of the facial skeleton were examined. The evaluation was based on CT-images of skulls from three historical populations, specifically from the Early Middle Ages, High Middle Ages and the early modern period. The current population was represented by CT-images of living people. We studied the facial skeletons of a total of 329 individuals, of which 183 were men and 146 women. The CT- images were used as a base for the creation of virtual 3D surface models. The facial skeleton was divided into three morphological units, which were further examined. These were the skeleton of the upper face, lower jaw and palate. The statistical processing was carried out applying methods of geometric morphometrics allowing the separate studying of the shape and size variability of the examined units. When comparing the size and shape differences between studied populations it is...
Sexual dimorphism of rat gut microbiota composition and intestinal immunity
Kalousová, Pavla ; Kovařík, Miroslav (advisor) ; Jílek, Petr (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Candidate: Pavla Kalousová Supervisor: PharmDr. Miroslav Kovařík, Ph.D. Title: Sexual dimorphism of rat gut microbiota composition and intestinal immunity Background and Aim: Many factors can influence the composition of gut microbiota and the immune system. It is well-known that one of those factors is sex. This sexual dimorphism can lead to a specifically adjusted treatment of diseases for different gender and nutritional interventions. This study focuses on analysing sexual differences in gut microbiota and intestinal immunity in adult rats. Methods: Caecal content from 12-week-old female and male Wistar rats were collected and analysed by DNA-sequencing technique to characterize microbiota composition. ELISA test was performed to quantify the concentration of IgA in faeces and gut wash. Flow cytometry determined the concentration of IgA-coating bacteria in faecal samples. Results: Metagenomic analysis revealed that female gender presents 1 phylum, 4 families, 13 genera, and 13 species which are not present in male rats. Only one male-specific colonization was observed at the species level. Quantitative analysis showed a higher proportion of Firmicutes phylum in males which was associated with...
Morphology of the mandible with regard to the demographic structure of the early medieval burial area Mikulčice
Thon, Tomáš ; Bejdová, Šárka (advisor) ; Velemínský, Petr (referee)
This Master's thesis focuses on the influence of socioeconomic status on the morphology of the mandible of individuals from the early medieval burial area in Mikulčice. This hillfort was an important center of power of the Great Moravian Empire with a stratified society. This work compares 2 different approaches on how to divide the inhabitants. The first of them is the division of individuals according to the location of graves into individuals from the castle, sub-castle, and hinterland. The second approach is the division of individuals according to the richness of grave equipment into individuals with rich and poor grave equipment. A different social status is associated mainly with different diets. Therefore, the attachments of the masticatory muscles are the most affected areas. A total of 132 individuals (59 males and 73 females) were analyzed. The material was evaluated by methods of geometric morphometrics. The used methods were CDP DCA, GPA, two-sample t-test, PCA, MANOVA, and SVM. Sexual dimorphism was observed in all sub-groups of the Mikulčice population. Men have larger mandibles with rami wider apart. The biggest differences are between individuals from the castle, the smallest between individuals with rich grave equipment. The distribution of individuals based on the location of...
Modelling of human palate surface development from 7 years to adulthood
Moravec, Tomáš ; Bejdová, Šárka (advisor) ; Zemková, Daniela (referee)
The diploma thesis deals with the differences in the development of the palate in girls and boys within five age groups in the age range of 7 to 19 years, using methods of geometric morphometry. Furthermore, the work deals with the monitoring of sexual dimorphism in the development of the palate. Understanding palate growth, knowledge of differences in its development and changes related to sexual dimorphism are very useful, as the results of this study will serve as a comparative standard for palate defects in the Czech population, but also for appropriate planning of orthodontic procedures. The material consists of 228 gypsum castings of palate without any pathologies, 112 of which belonged to boys and 116 girls of the Czech population. Thus, transverse data are used in our study. The subjects were divided into five age groups 7, 10, 12, 15 and 19 with respect to gender. Age changes of the entire palate surface were modeled using geometric morphometry methods (Coherent point drift - Dense correspondence analysis, Per vertex T- test and Principal component analysis). To visualize the results, superprojection color maps, maps of significance and superprojection. The results show the greatest variability in the form of palate in girls of groups 10 and 12 years and in boys of groups 10 years, and...

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