Original title: Antimicrobial peptides isolated from the venom of wild bee Panurgus calcaratus
Authors: Čujová, Sabína ; Monincová, Lenka ; Slaninová, Jiřina ; Bednárová, Lucie ; Čeřovský, Václav
Document type: Papers
Conference/Event: Biologically Active Peptides /12./, Praha (CZ), 2011-04-27 / 2011-04-29
Year: 2011
Language: eng
Abstract: Three novel peptides designated as PNG-1, PNG-K and PNG-R were isolated from the venom of the solitary bee Panurgus calcaratus. They exhibited antimicrobial activity against Grampositive and -negative bacteria and fungi. In this work we focused on the characterization of PNG-R which is unique 25 amino acid residues and two disulfide bridges containing peptide. The secondary structure of PNG-R was studied by circular dichroism spectroscopy measured in water and in the presence of trifluoroethanol or sodium dodecyl sulfate.
Keywords: alpha-Helical structures; antimicrobial peptides; bee venom; disulfide bridges; Panurgus calcaratus
Project no.: CEZ:AV0Z40550506 (CEP), GA203/08/0536 (CEP)
Funding provider: GA ČR
Host item entry: Biologically Active Peptides. 12th Conference, ISBN 978-80-86241-44-9

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0204309

Permalink: http://www.nusl.cz/ntk/nusl-81009


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Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers