Název: Determination of the effective charge and ionic mobilities of highly sulfated cyclodextrins by capillary isotachophoresis and zone electrophoresis
Autoři: Kašička, Václav ; Šolínová, Veronika ; Sázelová, Petra ; Koval, Dušan ; Vigh, G.
Typ dokumentu: Příspěvky z konference
Konference/Akce: Advances in Chromatography and Electrophoresis & Chiranal 2024, Olomouc (CZ), 20240617
Rok: 2024
Jazyk: eng
Abstrakt: Sulfated cyclodextrins (SCDs) belong to the most popular chiral selectors in capillary electrophoresis [1, 2]. SCDs are available as mixtures of randomly highly sulfated species (HSCDs) or as well defined single isomer compounds (SI-CDs). For the randomly HS-CDs, only an average degree of substitution (DS) is estimated but the isomeric heterogeneity and the charge distribution are not known. In the SI-CDs, the sulfatation positions and the DS are well specified. However, due to close vicinity of the sulfate groups in both types of SCDs, counterion condensation can occur in their molecules and their actual effective charge can be lower than number of sulfate groups. For that reason, the aim of this work was to estimate the degree of charge reduction in both types of SCDs using the procedure based on separation of SCDs and reference compounds by capillary isotachophoresis (CITP) and zone electrophoresis (CZE). \n
Klíčová slova: capillary electrophoresis; capillary isotachophoresis; sulfated cyclodextrins
Zdrojový dokument: Advances in Chromatography and Electrophoresis & Chiranal 2024, ISBN 978-80-244-6478-7

Instituce: Ústav organické chemie a biochemie AV ČR (web)
Informace o dostupnosti dokumentu: Dokument je dostupný na externích webových stránkách.
Externí umístění souboru: https://doivup.upol.cz/pdfs/doi/9900/06/7500.pdf
Původní záznam: https://hdl.handle.net/11104/0365810

Trvalý odkaz NUŠL: http://www.nusl.cz/ntk/nusl-678763


Záznam je zařazen do těchto sbírek:
Věda a výzkum > AV ČR > Ústav organické chemie a biochemie
Konferenční materiály > Příspěvky z konference