Název:
Unique exposure system for the whole body inhalation experiments with small animals
Autoři:
Večeřa, Zbyněk ; Mikuška, Pavel ; Dočekal, Bohumil ; Vojta, Šimon ; Míšek, Ivan ; Moravec, Pavel ; Smolík, Jiří Typ dokumentu: Příspěvky z konference Konference/Akce: NANOCON 2011. International Conference /3./, Brno (CZ), 2011-09-21 / 2011-09-23
Rok:
2011
Jazyk:
eng
Abstrakt: The especially inhalation chamber is constructed for chronic exposure studies of small animals to nanoparticles under strictly controlled conditions in frame of project „Study of transport of inhalated nano-sized particles (Pb, Cd) and their allocation in organs“. The inhalation chamber builds from a glass and stainless steel and makes possible long-term inhalation procedures (up to 60 days, 24 hours/day) with up to four discrete groups of mice population (up to 60 individuals each) or of rats population (up to 20 individuals each) under controlled illumination, temperature, relative humidity, doses (0.5 x 106 - 5 x 106 particles/cm3) and size (10-60 nm) of nano-sized particles which are synthesized via aerosol route in a hot wall tube flow reactor using metal organic precursors.
Klíčová slova:
chronic exposure studies of small animals; inhalation chamber; long-term inhalation procedures Číslo projektu: CEZ:AV0Z40310501 (CEP), CEZ:AV0Z40720504 (CEP), CEZ:AV0Z50450515 (CEP), GAP503/11/2315 (CEP) Poskytovatel projektu: GA ČR Zdrojový dokument: NANOCON 2011. Conference Proceedings, ISBN 978-80-87294-23-9
Instituce: Ústav analytické chemie AV ČR
(web)
Informace o dostupnosti dokumentu:
Dokument je dostupný v příslušném ústavu Akademie věd ČR. Původní záznam: http://hdl.handle.net/11104/0200160