Original title: Tail labelled oligonucleotide probes for the detection of DNA-protein interactions
Authors: Pivoňková, Hana ; Němcová, Kateřina ; Horáková Brázdilová, Petra ; Havran, Luděk ; Macíčková-Cahová, Hana ; Hocek, Michal ; Fojta, Miroslav
Document type: Papers
Conference/Event: Chemistry of Nucleic Acid Components /15./, Český Krumlov (CZ), 2011-06-05 / 2011-06-10
Year: 2011
Language: eng
Abstract: DNA-protein interactions can be monitored via different ways. We introduce novel, fast and simple approaches in DNA-protein interaction detection based on electrochemical measurements of DNA alone (structure-sensitive DNA sensing), or DNA modified with osmium tetroxide bearing nitrogenous ligands, or measurements of redox-active moieties enzymatically attached to the end of a DNA substrate thus forming a labeled tail (by terminal transferase).
Keywords: DNA; electrochemistry; tail labeling
Project no.: CEZ:AV0Z40550506 (CEP), CEZ:AV0Z50040507 (CEP), CEZ:AV0Z50040702 (CEP), LC512 (CEP), LC06035 (CEP), IAA400040901 (CEP), IAA400040903 (CEP), GAP301/11/2076 (CEP)
Funding provider: GA MŠk, GA MŠk, GA AV ČR, GA AV ČR, GA ČR
Host item entry: Chemistry of Nucleic Acid Components. 15th Symposium, ISBN 978-80-86241-37-1

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0198898

Permalink: http://www.nusl.cz/ntk/nusl-55850

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Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers
 Record created 2011-09-06, last modified 2020-04-20

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