Original title: Continuous monitoring of anthraquinone-based anticancer drugs by amperometric technique
Authors: Skalová, Štěpánka ; Fischer, J. ; Barek, J. ; Navrátil, Tomáš ; Krejčí, J. ; Kučerová, R. ; Vyskočil, V.
Document type: Papers
Conference/Event: International Students Conference on Modern Analytical Chemistry, Prague (CZ), 20190919
Year: 2019
Language: eng
Abstract: This contribution is focused on the development of electroanalytical methods for the monitoring of anthraquinone-based anticancer drugs in physiological solution by combination of liquid-flow system and dialysis catheter, possibly inserted into blood circulation of patients. For this purpose, amperometric detection with dual glassy carbon electrode was developed and derivate of these drugs, anthraquinone-2-sulphonate, was used as a model compound. Two different flow rates of carrier solution (physiological solution) were tested (specifically, 1 and 5 mu L min(-1)) and the dependence of peak currents of anthraquinone-2-sulphonate on its concentration was verified
Keywords: amperometric detection; anthracyclines; anthraquinone-2-sulphonate
Project no.: GA17-05387S (CEP), GA17-03868S (CEP)
Funding provider: GA ČR, GA ČR
Host item entry: PROCEEDINGS OF THE 15TH INTERNATIONAL STUDENTS CONFERENCE MODERN ANALYTICAL CHEMISTRY, ISBN 978-80-7444-068-7

Institution: J. Heyrovsky Institute of Physical Chemistry AS ČR (web)
Document availability information: Fulltext is available at external website.
External URL: http://web.natur.cuni.cz/analchem/isc/isc15.pdf
Original record: https://hdl.handle.net/11104/0339548

Permalink: http://www.nusl.cz/ntk/nusl-520560


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Conference materials > Papers