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Original title:
Degradation of polycaprolactone electrospun materials - methods of analysis
Authors: Havlíčková, K. ; Řezanka, M. ; Kobera, Libor ; Kuželová Košťáková, E. ; Lukáš, D. ; Jenčová, V.
Document type: Papers
Conference/Event: International Conference on Nanomaterials - Research & Application /13./ NANOCON, Brno (CZ), 20211020
Year: 2021
Language: eng
Abstract: Biodegradable electrospun materials are widely used for medical application. Polycaprolatone is polymer suitable for electrospinning technology and is very often used to create nanofibrous scaffolds for tissue engineering. The time to disintegration or biodegradation of such materials is very important here. However, testing is not entirely easy. It is not possible to create exactly body-like conditions in vitro. Moreover, it is not easy to find suitable analytical methods that would show exactly what happens in the nanofibrous polycaprolactone electrospun samples at certain stages of degradation, ie how the internal structure of decaying nanofibers changes. This paper describes the traditional use of methods for testing polycaprolatone nanofibers by enzymatically catalysed degradation. Morphological changes are studied using scanning electron microscope images. However, it also offers a non-traditional analysis of polycaprolactone electrospun materials using the ssNMR method.
Keywords: electrospinning; enzymatic degradation; nanofibers
Host item entry: NANOCON 2021 - Conference proceedings, ISBN 978-80-88365-00-6, ISSN 2694-930X
Note: Související webová stránka: https://www.confer.cz/nanocon/2021/4354-degradation-of-polycaprolactone-electrospun-materials-methods-of-analysis
Institution: Institute of Macromolecular Chemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0330780
Permalink: http://www.nusl.cz/ntk/nusl-508569
The record appears in these collections:
Research > Institutes ASCR > Institute of Macromolecular Chemistry
Conference materials > Papers
Authors: Havlíčková, K. ; Řezanka, M. ; Kobera, Libor ; Kuželová Košťáková, E. ; Lukáš, D. ; Jenčová, V.
Document type: Papers
Conference/Event: International Conference on Nanomaterials - Research & Application /13./ NANOCON, Brno (CZ), 20211020
Year: 2021
Language: eng
Abstract: Biodegradable electrospun materials are widely used for medical application. Polycaprolatone is polymer suitable for electrospinning technology and is very often used to create nanofibrous scaffolds for tissue engineering. The time to disintegration or biodegradation of such materials is very important here. However, testing is not entirely easy. It is not possible to create exactly body-like conditions in vitro. Moreover, it is not easy to find suitable analytical methods that would show exactly what happens in the nanofibrous polycaprolactone electrospun samples at certain stages of degradation, ie how the internal structure of decaying nanofibers changes. This paper describes the traditional use of methods for testing polycaprolatone nanofibers by enzymatically catalysed degradation. Morphological changes are studied using scanning electron microscope images. However, it also offers a non-traditional analysis of polycaprolactone electrospun materials using the ssNMR method.
Keywords: electrospinning; enzymatic degradation; nanofibers
Host item entry: NANOCON 2021 - Conference proceedings, ISBN 978-80-88365-00-6, ISSN 2694-930X
Note: Související webová stránka: https://www.confer.cz/nanocon/2021/4354-degradation-of-polycaprolactone-electrospun-materials-methods-of-analysis
Institution: Institute of Macromolecular Chemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0330780
Permalink: http://www.nusl.cz/ntk/nusl-508569
The record appears in these collections:
Research > Institutes ASCR > Institute of Macromolecular Chemistry
Conference materials > Papers
Record created 2022-09-28, last modified 2023-04-09