Original title: Aldrithiol-2 as a new derivatization agent for double bond localization in unsaturated compounds by mass spectrometry
Authors: Strmeň, Timotej ; Cvačka, Josef
Document type: Papers
Conference/Event: International Students Conference „Modern Analytical Chemistry“ /15./, Praha (CZ), 20190919
Year: 2019
Language: eng
Abstract: A new method for localizing double bonds in lipids using derivatization with 2,2'-clipyridyl disulfide (Aldrithio-2) and electrospray ionization mass spectrometry (EST-MS) is presented. The derivatization introduces a permanent charge to the molecules. When collisionally activated, the derivatives provide diagnostic peaks useful for establishing the position of the original double bond. Since permanent charge of the derivative significantly increases the detectability of analytes, the method works well also for of very low polarity like hydrocarbons.
Keywords: aldrithiol-2; double bond; electrospray; lipids; mass spectrometry
Host item entry: Proceedings of the 15th International Students Conference „Modern Analytical Chemistry“, ISBN 978-80-7444-068-7

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0302327

Permalink: http://www.nusl.cz/ntk/nusl-407952


The record appears in these collections:
Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers