Home > Conference materials > Papers > Characterization of valinomycin binding with alkali metal ions by capillary affinity electrophoresis and density functional theory
Original title:
Characterization of valinomycin binding with alkali metal ions by capillary affinity electrophoresis and density functional theory
Authors:
Ehala, Sille ; Dybal, Jiří ; Makrlík, E. ; Kašička, Václav Document type: Papers Conference/Event: Biologically Active Peptides. Conference /11./, Praha (CZ), 2009-04-22 / 2009-04-24
Year:
2009
Language:
eng Abstract:
Capillary affinity electrophoresis (CAE) and quantum mechanical density functional theory (DFT) have been applied to the study of non-covalent binding of valinomycin (Val), an antibiotic dodecadepsipeptide ionophore, with alkali metal ions, Li+, Na+, K+, Rb+ and Cs+, in methanol. The binding constants (Kb) of Val-alkali metal ion complexes were evaluated by CAE. The most probable structures of the Val-alkali metal ion complexes were proposed by DFT.
Keywords:
capillary affinity electrophoresis; density funtional theory; valinomycin Project no.: CEZ:AV0Z40550506 (CEP), CEZ:AV0Z40500505 (CEP), GA203/08/1428 (CEP), 1ET400500402 (CEP) Funding provider: GA ČR, GA AV ČR Host item entry: Biologically Active Peptides. 11th Conference, ISBN 978-80-86241-31-9
Institution: Institute of Organic Chemistry and Biochemistry AS ČR
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Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0177742