Original title: Separation of rotamers of 5-nitrosopyrimidines by capillary electrophoresis
Authors: Štěpánová, Sille ; Procházková, Eliška ; Čechová, Lucie ; Žurek, Jiří ; Janeba, Zlatko ; Dračínský, Martin ; Kašička, Václav
Document type: Papers
Conference/Event: Advances in Chromatography and Electrophoresis & Chiranal 2018, Olomouc (CZ), 20180129
Year: 2018
Language: eng
Abstract: A new capillary electrophoresis (CE) method was developed for the separation of a new type of stereoisomers - rotamers of polysubstituted 5-nitrosopyrimidine derivatives. Partial separation of some rotamers was obtained in sodium borate, pH 9.3, or in Tris-phosphate, pH 2.2, background electrolytes (BGEs) free of cyclodextrins (CDs). However, the best, baseline separations of the rotamers of 5-nitrosopyrimidines were achieved in sodium borate BGE, pH 9.3, containing 20 mg/mL beta-CD as stereoselector, or in Tris-phosphate BGE, pH 2.2, with carboxymethyl-beta-CD as stereoselector.
Keywords: 5-nitrosopyrimidines; capillary electrophoresis; rotamers
Project no.: GA15-01948S (CEP), GA17-10832S (CEP)
Funding provider: GA ČR, GA ČR
Host item entry: Advances in Chromatography and Electrophoresis & Chiranal 2018

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0286869

Permalink: http://www.nusl.cz/ntk/nusl-386561


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Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers