Home > Conference materials > Papers > Isosteric phosphonate 3'-O-P-CH2-O-4'C internucleotide linkage: Attempts to get more data on its stereochemistry
Original title:
Isosteric phosphonate 3'-O-P-CH2-O-4'C internucleotide linkage: Attempts to get more data on its stereochemistry
Translated title:
Isosterní fosfonátová internukleotidová vazba typu 3'-O-P-CH2-O-4'C: Cesta k dalším údajům o její stereochemii
Authors:
Točík, Zdeněk ; Barvík, I. ; Buděšínský, Miloš ; Rosenberg, Ivan Document type: Papers Conference/Event: Chemistry of Nucleic Acid Components /13./, Špindlerův Mlýn (CZ), 2005-09-03 / 2005-09-09
Year:
2005
Language:
eng Abstract:
[eng][cze] Synthesis of model thymidine dinucleoside phosphonate containing 3´-O-P-CH2-O-4´C isosteric linkage in 13C-labelled form enabled its NMR conformational description which was further compared with MDS and ab initio studies.Byl připraven modelový thymidinový dinukleosidfosfonát s isosterní 3´-O-P-CH2-O-4´C internukleotidovou vazbou značenou 13C, což umožnilo konformační popis vazby pomocí NMR a jeho následné srovnání s údaji MDS a ab initio studie.
Keywords:
isosteric; phosphonate; stereochemistry Project no.: CEZ:AV0Z40550506 (CEP), GA203/05/0827 (CEP) Funding provider: GA ČR Host item entry: Chemistry of Nucleic Acid Components, ISBN 80-86241-25-4
Institution: Institute of Organic Chemistry and Biochemistry AS ČR
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Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0111645