Original title: Vliv léčby sertralinem na vybrané metabolické a antropometrické parametry depresivních osob
Translated title: The influence of sertraline treatment on the metabolic and antropometric parameters in people with depression
Authors: Podlipný, Jiří ; Beran, Jiří (advisor) ; Filipovský, Jan (referee) ; Jirák, Roman (referee)
Document type: Doctoral theses
Year: 2010
Language: cze
Abstract: [cze] [eng]
1 Univerzita Karlova v Praze Lékařská fakulta v Plzni Psychiatrická klinika VLIV LÉČBY SERTRALINEM NA VYBRANÉ METABOLICKÉ A ANTROPOMETRICKÉ PARAMETRY DEPRESIVNÍCH OSOB THE INFLUENCE OF SERTRALINE TREATMENT ON THE METABOLIC AND ANTHROPOMETRIC PARAMETERS IN PEOPLE WITH DEPRESSION Autoreferát dizertační práce Doktorský studijní program vědního oboru: Neurologie a psychiatrie Plzeň 2010 MUDr. Jiří Podlipný 2 Dizertační práce byla vypracována v rámci kombinovaného doktorského studijního programu na Psychiatrické klinice LF UK a FN v Plzni za podpory výzkumného úkolu grantového projektu IGA MZ NA 7434-3 (2003 - 2005) "Zlepšení rizikového profilu ICHS ovlivněním skryté deprese". Uchazeč: MUDr. Jiří Podlipný Psychiatrická klinika LF UK a FN v Plzni Alej svobody 80 304 60 Plzeň Školitel: Doc. MUDr. Jiří Beran, CSc. Psychiatrická klinika LF UK a FN v Plzni Oponenti: Prof. MUDr. Jan Filipovský, CSc. II. interní klinika LF UK a FN v Plzni Doc. MUDr. Roman Jirák, CSc. Psychiatrická klinika 1. LF UK a VFN v Praze Stanovisko k dizertační práci vypracovalo vedení Psychiatrické kliniky LF UK a FN v Plzni. Autoreferát byl rozeslán dne ................................................................... Obhajoba dizertační práce se koná dne ....24.6.2010........ v ...14:00......hodin v seminární místnosti Neurologické kliniky... Introduction: Pharmacotherapy with antidepressants can cause a metabolic risk, can be neutral in terms of metabolism or can perform a metabolic benefit for the treated patients. Objective: The aim of the presented study is to assess the effects of long-term use of sertraline on the particular laboratory and anthropometric parameters in somaticaly healthy or compensated outpatients treated for unipolar depression. Methods: The study was performed in cooperation of Centre of Preventive Cardiology (CPC) of 2nd Department of Internal Medicine and Department of Psychiatry of Charles University in Prague, Faculty of Medicine in Plzeň (Pilsen) and University Hospital Plzeň, Czech Republic. A screening of risk factors in relation to the development of cardiovascular (CV) diseases and metabolic syndrom was carried out in 350 people from the cohort Pilsen Longitudinal Study III (PILS III) at CPC. The participants filled in a Czech version of the Zung Self-Rating Depression Scale (SDS) simultaneously with the screening. Those of them scoring up the threshold set for the suspicion of depression in SDS were invited to the department of psychiatry outpatient's office in order to undertake a psychiatric examination. There were 31 persons in total fulfilling the following criteria: (1) aduld patients diagnosed with...

Institution: Charles University Faculties (theses) (web)
Document availability information: Available in the Charles University Digital Repository.
Original record: http://hdl.handle.net/20.500.11956/23414

Permalink: http://www.nusl.cz/ntk/nusl-278229


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Universities and colleges > Public universities > Charles University > Charles University Faculties (theses)
Academic theses (ETDs) > Doctoral theses