Název:
Voltammetric determination of homovanillic acid at boron doped diamond electrode for hollow fibre microextraction
Autoři:
Hrdlička, V. ; Barek, J. ; Navrátil, Tomáš Typ dokumentu: Příspěvky z konference Konference/Akce: ISC Modern Analytical Chemistry /12./, Prague (CZ), 20160922
Rok:
2016
Jazyk:
eng
Abstrakt: Presented work deals with hollow-fibre assisted liquid/liquid/liquid microextraction (HF-LPME) and subsequent voltammetric detection of clinical biomarker homovanillic acid (HVA). Three main areas are discussed: hollow fibre assisted extraction of HVA, voltammetric detection of HVA under basic conditions, and sensing in very small volumes. Using HF-PLME, HVA was extracted with 1-octanol as a supported liquid membrane with enrichment factor of 55 after 60 minutes of extraction. A novel method of miniaturized voltammetric determination of HVA using cathodically pretreated boron doped diamond electrode was also developed. Using differential pulse voltammetry, limit of detection, limit of quantificati was 1.9 mu mol dm(-3) on 6.6 mu mol dm(-3).
Klíčová slova:
biomarkers; boron doped diamond electrode; hollow-fibre Zdrojový dokument: Proceedings of the 12th International students conference Modern Analytical Chemistry, ISBN 978-80-7444-044-1
Instituce: Ústav fyzikální chemie J. Heyrovského AV ČR
(web)
Informace o dostupnosti dokumentu:
Dokument je dostupný v příslušném ústavu Akademie věd ČR. Původní záznam: http://hdl.handle.net/11104/0268393