Home > Conference materials > Papers > Determination of stability constants of [Gly6]-antamanide complexes with small cations by affinity capillary electrophoresis
Original title:
Determination of stability constants of [Gly6]-antamanide complexes with small cations by affinity capillary electrophoresis
Authors:
Pangavhane, Sachin ; Makrlík, E. ; Ruzza, P. ; Kašička, Václav Document type: Papers Conference/Event: Advances in Chromatography and Electrophoresis & Chiranal 2016, Olomouc (CZ), 20160606
Year:
2016
Language:
eng Abstract:
Affinity capillary electrophoresis (ACE) was employed for the determination of apparent stability constants Kst of complexes of cyclic peptide [Gly6]-antamanide ([Gly6]-AA) with alkali and alkali-earth metal ions: Li+, Na+, K+, Rb+, Cs+, NH4+, and Ca2+. Kst was determined from the dependence of effective mobility of [Gly6]-AA on the concentration of these ions in the background electrolyte using the non-linear regression analysis. Kst were found to be in the range 13.3 – 26.3.
Keywords:
[Gly6]-antamanide; affinity capillary electrophoresis; stability constant Project no.: GA15-01948S (CEP) Funding provider: GA ČR Host item entry: Advances in Chromatography and Electrophoresis & Chiranal 2016, ISBN 978-80-244-4961-6
Institution: Institute of Organic Chemistry and Biochemistry AS ČR
(web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0267200