Název:
Novel, versatile capillary electrophoresis instrument with laser induced fluorescence for analysis of various lipid peroxidation biomarkers
Autoři:
Lačná, J. ; Foret, František ; Kubáň, Petr Typ dokumentu: Příspěvky z konference Konference/Akce: CECE 2016. International Interdisciplinary Meeting on Bioanalysis /13./, Brno (CZ), 20161017
Rok:
2016
Jazyk:
eng
Abstrakt: In this work we have developed a new sensitive method for quantitation of MDA in\nbiological samples by CE-LIF with LOD about 1.7 nM. First part of the work was\ndevoted to the construction of a new CE-LIF system. Then the derivatization process\nof MDA by TBA was optimized. The ability to use this method for the detection of\nMDA in a biological samples, such as EBC and plasma, was also demonstrated. For the\nfirst time it was possible to detect MDA in EBC samples by CE. Other biomarkers are\nnow being studied.
Klíčová slova:
biomarkers; CE-LIF; lipids; malondialdehyde Zdrojový dokument: CECE 2016. 13th International Interdisciplinary Meeting on Bioanalysis, ISBN 978-80-904959-4-4
Instituce: Ústav analytické chemie AV ČR
(web)
Informace o dostupnosti dokumentu:
Dokument je dostupný v repozitáři Akademie věd. Původní záznam: http://hdl.handle.net/11104/0265912