Home > Conference materials > Papers > Novel, versatile capillary electrophoresis instrument with laser induced fluorescence for analysis of various lipid peroxidation biomarkers
Original title:
Novel, versatile capillary electrophoresis instrument with laser induced fluorescence for analysis of various lipid peroxidation biomarkers
Authors:
Lačná, J. ; Foret, František ; Kubáň, Petr Document type: Papers Conference/Event: CECE 2016. International Interdisciplinary Meeting on Bioanalysis /13./, Brno (CZ), 20161017
Year:
2016
Language:
eng Abstract:
In this work we have developed a new sensitive method for quantitation of MDA in\nbiological samples by CE-LIF with LOD about 1.7 nM. First part of the work was\ndevoted to the construction of a new CE-LIF system. Then the derivatization process\nof MDA by TBA was optimized. The ability to use this method for the detection of\nMDA in a biological samples, such as EBC and plasma, was also demonstrated. For the\nfirst time it was possible to detect MDA in EBC samples by CE. Other biomarkers are\nnow being studied.
Keywords:
biomarkers; CE-LIF; lipids; malondialdehyde Host item entry: CECE 2016. 13th International Interdisciplinary Meeting on Bioanalysis, ISBN 978-80-904959-4-4
Institution: Institute of Analytical Chemistry AS ČR
(web)
Document availability information: Fulltext is available in the digital repository of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0265912