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Original title:
The first experiencies with new exposure system for the whole body inhalation experiments with small animals
Authors: Večeřa, Zbyněk ; Mikuška, Pavel ; Moravec, Pavel ; Smolík, Jiří
Document type: Papers
Conference/Event: NANOCON 2012. Mezinárodní konference /4./, Brno (CZ), 2012-10-23 / 2012-10-25
Year: 2013
Language: eng
Abstract: The first experiences with an inhalation chamber constructed for long-term exposure studies of small animals to nanoparticles under strictly controlled experimental conditions. The inhalation chamber was build from a glass and stainless steel and allows possible long-term inhalation procedures with up to four discrete groups of mice or of rats population under controlled illumination, temperature, relative humidity and pressure. Doses up to 1 x 10(6) particles/cm(3) and size (10-60 nm) of nano-sized particles were synthesized via aerosol route in a hot wall tube flow reactor using thermal decomposition of metal organic precursors. The function of exposure system for whole body inhalation experiments was studied under real conditions in period from May to September 2012. No animals were used within this trial experiment.
Keywords: inhalation chamber; nanoparticles; small animals
Project no.: GAP503/11/2315 (CEP), GBP503/12/G147 (CEP)
Funding provider: GA ČR, GA ČR
Host item entry: NANOCON 2012, Conference Proceedings, ISBN 978-80-87294-35-2
Institution: Institute of Analytical Chemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0240947
Permalink: http://www.nusl.cz/ntk/nusl-178205
The record appears in these collections:
Research > Institutes ASCR > Institute of Analytical Chemistry
Conference materials > Papers
Authors: Večeřa, Zbyněk ; Mikuška, Pavel ; Moravec, Pavel ; Smolík, Jiří
Document type: Papers
Conference/Event: NANOCON 2012. Mezinárodní konference /4./, Brno (CZ), 2012-10-23 / 2012-10-25
Year: 2013
Language: eng
Abstract: The first experiences with an inhalation chamber constructed for long-term exposure studies of small animals to nanoparticles under strictly controlled experimental conditions. The inhalation chamber was build from a glass and stainless steel and allows possible long-term inhalation procedures with up to four discrete groups of mice or of rats population under controlled illumination, temperature, relative humidity and pressure. Doses up to 1 x 10(6) particles/cm(3) and size (10-60 nm) of nano-sized particles were synthesized via aerosol route in a hot wall tube flow reactor using thermal decomposition of metal organic precursors. The function of exposure system for whole body inhalation experiments was studied under real conditions in period from May to September 2012. No animals were used within this trial experiment.
Keywords: inhalation chamber; nanoparticles; small animals
Project no.: GAP503/11/2315 (CEP), GBP503/12/G147 (CEP)
Funding provider: GA ČR, GA ČR
Host item entry: NANOCON 2012, Conference Proceedings, ISBN 978-80-87294-35-2
Institution: Institute of Analytical Chemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0240947
Permalink: http://www.nusl.cz/ntk/nusl-178205
The record appears in these collections:
Research > Institutes ASCR > Institute of Analytical Chemistry
Conference materials > Papers
Record created 2014-12-11, last modified 2021-11-24