Original title: Chiral analysis of beta-alanyl-D,L-tyrosine and its derivatives by capillary electrophoresis with 2-hydroxypropyl-beta-cyclodextrin stereoselector
Authors: Sázelová, Petra ; Šolínová, Veronika ; Schimperková, Tereza ; Mášová, Alice ; Jiráček, Jiří ; Kašička, Václav
Document type: Papers
Conference/Event: International Symposium Advances in Chromatography and Electrophoresis and Chiranal, Olomouc (CZ), 2012-06-11 / 2012-06-14
Year: 2012
Language: eng
Abstract: A new capillary electrophoretic method was developed for separation of enantiomers of antimicrobial dipeptide betha-Ala-D,L-Tyr and its derivatives using 50 mM Tris-phosphate, pH 2.50, as background electrolyte and 2-hydroxypropyl-betha-cyclodextrin at concentrations 20 – 60 mg/mL as chiral selector. In addition, association constants of complexes of the enatiomers of dipeptide betha-Ala-D,L-Tyr and its derivatives with 2-hydroxypropyl-betha-cyclodextrin chiral selector were determined.
Keywords: antimicrobial peptides; capillary zone electrophoresis; chiral analysis
Project no.: GA203/08/1428 (CEP), GAP206/12/0453 (CEP)
Funding provider: GA ČR, GA ČR
Host item entry: Acta Universitatis Palackianae Olomucensis. Facultas Rerum Naturalium. Chemica 50S, ISBN 978-80-244-3115-4, ISSN 0232-0061

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0216660

Permalink: http://www.nusl.cz/ntk/nusl-136059


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