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Assessment of runoff conditions on flow in the Morava river basin
Holá, Lucie ; Niklová, Věra (referee) ; Uhmannová, Hana (advisor)
The diploma thesis deals with the design of nature close to the flood protection of the city Prostějov at the confluence of the watercourses Romže and Hloučely and the flow Valova (Romže). In canculations there was solved capacity of individual sections and canculation of levels for one-year, five-year and twenty-year flow. For canculations there was used one-dimensional mathematical model HEC-RAS 5.0.3. Determination of roughness of bottom and slopes was based on personal visit. The result of this diploma thesis is evaluation of current state and proposal of a nature close to the flood protection in the individual streams in the city Prostějov. The thesis contains the calculation part and the drawing part documenting the proposed measure.
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Creation of a Client Database for a Financial Advisor
Holý, Vladimír ; Holá, Lucie (referee) ; Luhan, Jan (advisor)
This bachelor´s thesis deals with the formation of the database application in Microsoft Access 2003 that will serve to the financial advisors to make their communication with customers easy and faster. The contents include the formation of the proposal, charts, forms, arrangements and the visual database setting. The last part of the solution proposal deals with the important asset.
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Bussines Plan
Havránek, David ; Ing.Lucie Holá (referee) ; Hanušová, Helena (advisor)
Master’s thesis is based on creating of the business plan of founding company that provide consulting in wellness. The theoretical part describes basic notions and methods, which are needed for creating of business plan. The next part contains analysis of the current market situation. The last part deals with business plan itself and evaluation of efficiency of financial plan.
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Mathematical Model for Faculty Budget
Holá, Lucie ; Roupec, Jan (referee) ; Popela, Pavel (advisor)
The idea of this diploma thesis is an origin application of optimization models to solve a wage funds allocation problem on various institutes of each faculty. This diploma thesis includes an outline of linear programming models, nonlinear programming models, multiply programming models and parametric programming models. Studied questions are debating in wider context of distributing financial resources from the Budget of the Czech republic, through Ministry of education, youth and sports, universities, faculties after as much as various institutes. The accent is given on question of definition assessment scales of achievement criteria with general-purpose kvantification.
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Sedimentation reservoir on the stream Kuřimka
Holá, Lucie ; Julínek, Tomáš (referee) ; Uhmannová, Hana (advisor)
The goal of the bachelors work is a proposal of sedimentation tank on Kuřimka in the cadestral area of Moravské Knínice. In calculations there was made capacity of addressed section and calculation of levels for thirty-days water and selected N-year flow. One of the chapters was dedicated to evaluation of vegetative suite. For calculations there was used one-dimensional mathematical model HEC-RAS 4.1. Determination of roughness of bottom and slopes was based on personal visit. The result is determination of capacitive flow, evaluation of current state and proposal of sedimentation tank on the chosen estate. Bachelors work can be a contribution to another sedimentation tank in the area of Brněnská dam.
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Interplay between ghrelin and its novel endogenous antagonist LEAP2: possible role in the pathology of obesity
Holá, Lucie ; Maletínská, Lenka (advisor) ; Jurčovičová, Jana (referee) ; Malínská, Hana (referee)
The increasing number of overweight and obese individuals has become a major health issue in our society. The etiology of obesity often involves excessive hyperphagia, highlighting the importance of comprehensive understanding the regulation of food intake regulation in order to effectively treat this chronic condition. Ghrelin, a peripheral peptide hormone responsible for increasing food intake, directly affects the hypothalamus through the growth hormone secretagogue receptor (GHSR). Recently, it was found that liver expressed antimicrobial peptide 2 (LEAP2) naturally counteracts the effects of the GHSR as an inverse agonist. This makes LEAP2 a potential candidate for the development of anti-obesity treatment. This thesis explores the interaction between ghrelin and LEAP2 in the context of food intake regulation and obesity. Firstly, it focuses on modified N-terminal peptide LEAP2(1-14) and its lipidized analogs, examining their affinity to and activation of GHSR in vitro and in vivo. The results demonstrate that palmitoylated LEAP2(1-14) (palm-LEAP2(1-14)) exhibits the most pronounced affinity for GHSR, acts as GHSR inverse agonist, reduces food intake, inhibits growth hormone release, and shows increased stability in rat plasma. These findings suggest that palm-LEAP2(1-14) holds promise as an...
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Assessment of runoff conditions on flow in the Morava river basin
Holá, Lucie ; Niklová, Věra (referee) ; Uhmannová, Hana (advisor)
The diploma thesis deals with the design of nature close to the flood protection of the city Prostějov at the confluence of the watercourses Romže and Hloučely and the flow Valova (Romže). In canculations there was solved capacity of individual sections and canculation of levels for one-year, five-year and twenty-year flow. For canculations there was used one-dimensional mathematical model HEC-RAS 5.0.3. Determination of roughness of bottom and slopes was based on personal visit. The result of this diploma thesis is evaluation of current state and proposal of a nature close to the flood protection in the individual streams in the city Prostějov. The thesis contains the calculation part and the drawing part documenting the proposed measure.
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Gender differences in risk attitude among Czech high school students
Holá, Lucie ; Jeřábek, Hynek (advisor) ; Tuček, Milan (referee)
The diploma thesis "Gender differences in risk attitude among Czech high school students" discusses how people deal with risk in everyday life. The first part of the paper investigates the forming of risk perception, and the factors that influence the process. Social and cultural structures are of high importance, but also individual factors (such as gender or personal experiences) as well as media representation matter. Risk perception plays a key role in decision-making in situations dealing with uncertainty and the paper asserts that it is possible to model risk behaviour and make predictions accordingly. The second part of the paper presents research on risk attitudes among Czech high school students. It deals with gender differences and students' willingness to risk in three key domains: social, health and leisure time. The model used in the paper focuses on students' willingness to participate in a given activity, their perception of the probability of negative outcomes, and the degree of pleasure derived from the activity. Research indicates that a) men are more willing to risk in health and leisure time related activities, whereas women are more daring in social activities; b) students coming from academically oriented schools are more willing to risk in social activities than students...
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