National Repository of Grey Literature 9 records found  Search took 0.01 seconds. 
Regulation of triglyceride metabolism in circulation in postprandial phase.
Zemánková, Kateřina
Increased triglyceride (TG) concentration has been generally accepted as a risk factor for ischemic heart disease and, therefore, lowering TG is therapeutic target that should reduce cardiovascular disease risk. Traditionally, concentration of TG is measured in the fasting state (8-12 hours after an overnight fasting) mainly because the rise in TG levels after meal leads to the high variation in TG values. However, human beings spend larger portion of the day in a postprandial state and postprandial hypertriglyceridemia may then play a substantial role in determination of cardiovascular disease risk. The increased and prolonged postprandial lipemia has been found in patients with coronary heart disease. Moreover, recent data from Copenhagen Heart Study point out that the non-fasting TG concentration is associated with cardiovascular disease risk more tightly than the fasting TG concentration. Importantly, concentration of non-fasting TG is substantially affected by individual behavioural habits such as diet composition and physical activity. It remains to be determined whether it would be appropriate to identify individuals at higher risk of cardiovascular disease due to increased postprandial TG using tolerance test analogous to glucose tolerance test. The protocol of standardized fat tolerance...
Regulation of triglyceride metabolism in circulation in postprandial phase.
Zemánková, Kateřina ; Kovář, Jan (advisor) ; Kazdová, Ludmila (referee) ; Zlatohlávek, Lukáš (referee)
Increased triglyceride (TG) concentration has been generally accepted as a risk factor for ischemic heart disease and, therefore, lowering TG is therapeutic target that should reduce cardiovascular disease risk. Traditionally, concentration of TG is measured in the fasting state (8-12 hours after an overnight fasting) mainly because the rise in TG levels after meal leads to the high variation in TG values. However, human beings spend larger portion of the day in a postprandial state and postprandial hypertriglyceridemia may then play a substantial role in determination of cardiovascular disease risk. The increased and prolonged postprandial lipemia has been found in patients with coronary heart disease. Moreover, recent data from Copenhagen Heart Study point out that the non-fasting TG concentration is associated with cardiovascular disease risk more tightly than the fasting TG concentration. Importantly, concentration of non-fasting TG is substantially affected by individual behavioural habits such as diet composition and physical activity. It remains to be determined whether it would be appropriate to identify individuals at higher risk of cardiovascular disease due to increased postprandial TG using tolerance test analogous to glucose tolerance test. The protocol of standardized fat tolerance...
Marriage
Zemánková, Kateřina ; Salač, Josef (advisor) ; Švestka, Jiří (referee)
Marriage The aim of this thesis is to describe legal institution of marriage - from the conclusion of marriage to the ending of it - according to the current legislation. I compare main changes introduced by the new Civil Code with legislation before 1st of January 2014. The reason I chose this topic was the fact that institute of marriage affects everyday life of almost every individual. My thesis is composed of five chapters. Each of them deals with different aspects of marriage. Besides these five chapters this thesis includes Introduction, Conclusion, Index of Appendices and the List of Bibliographical References. Chapter one concentrates on the most important changes in the Family law area during the modern history, including recent recodification of private law. This chapter also contains summary of the main legal sources of marital law and examines the term marriage itself and its purpose. Chapter two focuses on the conclusion of marriage. Main focus is on engagement, the actual process of marriage, the purpose of marriage, proceedings preceding the conclusion of marriage and the types of forms of marriage. Conclusion of marriage based on extraordinary situation, qualifications to conclude marriage and its legal impediments are also discussed. Chapter three discusses putative marriage and...
Regulation of lipoprotein lipase activity in circulation
Zemánková, Kateřina ; Kovář, Jan (advisor) ; Vrablík, Michal (referee)
Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism. The enzyme catalyzes hydrolysis of triacylglycerols (TG) of chylomicrons and of very low density lipoproteins (VLDL). However, the mechanisms involved in the regulation of this protein are not fully understood yet. Therefore, the aim of the theses is to study selected aspects of LPL activity regulation. Recently discovered apolipoprotein A-V (apo A-V) substantially affects triglyceridemia and it is presumed that it may function as LPL activator. However, its concentration in the blood is extremely low and we therefore investigated whether most of apo A-V could be bound to the heparan sulfate proteoglycan (HSPG) of vascular wall similarly to LPL. Intravenous heparin application in healthy volunteers resulted in an expected increase in LPL activity but apo A-V concentration did not change. Our results do not support the hypothesis that most of apo A-V is bound to HSPG of the capillary endothelium. An alcohol consumption plays also a role in LPL regulation - the long-term moderate alcohol consumption is known to increase enzyme activity; on the contrary, it is presumed that LPL activity is inhibited immediately after alcohol consumption. However, the direct evidence for such a premise is missing. The other aim of the theses was to...
Stress of endoplasmic reticulum and its role for the development of adipose tissue inflammation
Zemánková, Kateřina ; Rossmeislová, Lenka (advisor) ; Janovská, Petra (referee)
Endoplasmic reticulum (ER) is a cellular organelle responsible for folding of proteins that are then transported to the various places in the cell or secreted. It is also crucial for the synthesis of triglycerides. Metabolic imbalance leads to ER stress and consequently triggers signaling pathway, which is called unfolded-protein response (UPR). The aim of this pathway is to alleviate ER stress, restore natural homeostasis and prevent death of cell. At the same time however, it activates stress kinases and other factors that may perturb insulin signaling and increase expression of proinflammatory cytokines. These signs are characteristic for human obesity, which is associated with reduced tissue's sensitivity to insulin and is considered as a disease with low level of inflammation. Recent studies have suggested that the source of proinflammatory cytokines in obesity are stressed adipocytes and macrophage infiltrated into adipose tissue. Indeed, it has been demonstrated that stress of endoplasmic reticulum is significantly increased in adipose tissue of obese individuals. Weight loss associated with reduction of adipose tissue mass decreases stress while lowers both, the production of proinflammatory cytokines and insulin resistence. This work aims to collect and discuss these new findings, which...
Study of links between biogenic VOC emissions and concentration of tropospheric ozone
Zemánková, Kateřina
Title of dissertation: Study of links between biogenic VOC emissions and concentration of tropospheric ozone Kateřina Zemánková, 2010 Dissertation directed by: doc. RNDr. Josef Brechler, CSc. Dept. of Meteorology and Environment Protection, Faculty of Mathematics and Physics, Charles University in Prague Presented work focuses on influence of volatile organic compounds from biogenic sources on concentration of tropospheric ozone. Volatile organic compounds (VOC) play an important role in the tropospheric chemical system. Together with oxides of nitrogen they form two major components of reactions leading to low-level ozone formation. Volatile organic compounds are emitted into the atmosphere from an- thropogenic as well as from biogenic sources. In global, VOCs from natural sources are approximately ten times higher in magnitude than those of anthropogenic origin. Biogenic VOCs are emitted from various sources among which the forest ecosystems predominate. Group of VOCs of natural origin comprises wide range of chemical com- pounds. Those emitted in highest concentrations are isoprene and group of monoter- penes. Emissions of biogenic VOCs from the area of the Czech Republic have been es- timated based on the high resolution land cover data giving detailed information of sigle tree species...
Study of links between biogenic VOC emissions and concentration of tropospheric ozone
Zemánková, Kateřina ; Brechler, Josef (advisor) ; Bednář, Jan (referee) ; Braniš, Martin (referee)
Title of dissertation: Study of links between biogenic VOC emissions and concentration of tropospheric ozone Kateřina Zemánková, 2010 Dissertation directed by: doc. RNDr. Josef Brechler, CSc. Dept. of Meteorology and Environment Protection, Faculty of Mathematics and Physics, Charles University in Prague Presented work focuses on influence of volatile organic compounds from biogenic sources on concentration of tropospheric ozone. Volatile organic compounds (VOC) play an important role in the tropospheric chemical system. Together with oxides of nitrogen they form two major components of reactions leading to low-level ozone formation. Volatile organic compounds are emitted into the atmosphere from an- thropogenic as well as from biogenic sources. In global, VOCs from natural sources are approximately ten times higher in magnitude than those of anthropogenic origin. Biogenic VOCs are emitted from various sources among which the forest ecosystems predominate. Group of VOCs of natural origin comprises wide range of chemical com- pounds. Those emitted in highest concentrations are isoprene and group of monoter- penes. Emissions of biogenic VOCs from the area of the Czech Republic have been es- timated based on the high resolution land cover data giving detailed information of sigle tree species...
Interior Design of a Café
Zemánková, Kateřina ; Kolesár, Zdeno (referee) ; Zdařil, Zdeněk (advisor)
The thesis deals with the reconstruction of the café in a historic building on Svoboda Square in Mohelnice. To the revitalized interior, dominated by brick vault was introduced a new and fresh design. The café has two basic spaces. In the first lighter room is located bar and a few tables with long benches and chairs. The back room features a private sitting area overlooking the atrium of the building. Simple shapes and natural materials create contrast with the historic vault. Use indirect lighting is achieved pleasant and intimate atmosphere. An essential element of the interior is a custom made chair that their morphology fit into the concept of the café.
Atlas podnebí České republiky a regionalizace výstupů modelů všeobecné cirkulace atmosféry pro potřeby území České republiky: Regionalizace výstupů modelů všeobecné cirkulace atmosféry pro potřeby území České republiky
Univerzita Karlova v Praze, Matematicko-fyzikální fakulta, Praha ; Národní klimatický program České republiky ; Dubrovský, Martin ; Huth, Radan ; Zemánková, Kateřina ; Demeterová, Alžběta ; Vlček, Ondřej ; Borák, Matouš ; Chládová, Zuzana ; Pišoft, Petr ; Mikšovský, Jiří ; Halenka, Tomáš ; Raidl, Aleš ; Kalvová, Jaroslava
Dílčí projekt 02 řeší cíl projektu VaV/740/2/03 - posoudit možnosti regionalizace výstupů globálních klimatických modelů nelineárními metodami pro potřeby území České republiky a jejich porovnání s lineárními postupy. Dílčí projekt je rozdělený do dvou základních částí: A. Regionalizace výstupů globálních klimatických modelů lineárními metodami. B. Regionalizace výstupů globálních klimatických modelů nelineárními metodami. Závěrečná zpráva je složena ze zpráv za bod A a B a CD, na kterém jsou uloženy výsledné řady teplot a srážek, získané regionalizací modelu HadCM3, a rešerše lineárních postupů regionalizace.

See also: similar author names
1 Zemánková, K.
1 Zemánková, Karolína
2 Zemánková, Kristýna
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