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Original title:
Synthesis of Fluorinated Methyl β-Lactosides
Authors: Krčil, Aleš
Document type: Papers
Conference/Event: Bažant Postgraduate Conference 2024, Prague (CZ), 20240605
Year: 2024
Language: eng
Abstract: In my contribution, I will describe the synthesis of a complete series of mono-deoxyfluorinated methyl β-lactosides (1–7). Their affinity towards hgals will be determined by analytical method ELISA. The synthesis relies on monosaccharide building blocks, which serves as key intermediates that are transformed into the target products through glycosylation followed by final deprotection steps.
Keywords: deoxyfluorination; flurinated carbohydrates; galectin
Project no.: GA23-05146S (CEP)
Funding provider: GA ČR
Host item entry: Proceedings of Abstracts, ISBN 978-80-86186-32-0
Rights: This work is protected under the Copyright Act No. 121/2000 Coll.
Institution: Institute of Chemical Process Fundamentals AS ČR (web)
Original record: https://hdl.handle.net/11104/0354030
Permalink: http://www.nusl.cz/ntk/nusl-616433
The record appears in these collections:
Research > Institutes ASCR > Institute of Chemical Process Fundamentals
Conference materials > Papers
Authors: Krčil, Aleš
Document type: Papers
Conference/Event: Bažant Postgraduate Conference 2024, Prague (CZ), 20240605
Year: 2024
Language: eng
Abstract: In my contribution, I will describe the synthesis of a complete series of mono-deoxyfluorinated methyl β-lactosides (1–7). Their affinity towards hgals will be determined by analytical method ELISA. The synthesis relies on monosaccharide building blocks, which serves as key intermediates that are transformed into the target products through glycosylation followed by final deprotection steps.
Keywords: deoxyfluorination; flurinated carbohydrates; galectin
Project no.: GA23-05146S (CEP)
Funding provider: GA ČR
Host item entry: Proceedings of Abstracts, ISBN 978-80-86186-32-0
Rights: This work is protected under the Copyright Act No. 121/2000 Coll.
Institution: Institute of Chemical Process Fundamentals AS ČR (web)
Original record: https://hdl.handle.net/11104/0354030
Permalink: http://www.nusl.cz/ntk/nusl-616433
The record appears in these collections:
Research > Institutes ASCR > Institute of Chemical Process Fundamentals
Conference materials > Papers
Record created 2024-06-15, last modified 2024-06-15
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