Název:
Bayesian Selective Transfer Learning for Patient-Specific Inference in Thyroid Radiotherapy
Autoři:
Murray, Sean Ernest ; Quinn, Anthony Typ dokumentu: Výzkumné zprávy
Rok:
2020
Jazyk:
eng
Edice: Research Report, svazek: 2388
Abstrakt: This research report outlines a selective transfer approach for Bayesian estimation of patient-specific levels of radioiodine activity in the thyroid during the treatment of differentiated thyroid carcinoma. The work seeks to address some limitations of previous approaches [4] which involve generic, non-selective transfer of archival data. It is proposed that improvements in patient-specific inferences may be achieved via transferring external population knowledge selectively. This involves matching the patient to a similar sub-population based on available metadata, generating a Gaussian Mixture Model within the partitioned data, and optimally transferring a data predictive distribution from the sub-population to the specific patient. Additionally, a performance evaluation method is proposed and early-stage results presented.
Klíčová slova:
Bayesian estimation; patient-specific inferences; thyroid carcinoma Číslo projektu: GA18-15970S (CEP) Poskytovatel projektu: GA ČR