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Original title:
Comparison of microbial interactions of zinc oxide nanomaterials in various size and shape
Authors: Rutherford, D. ; Jíra, J. ; Mičová, J. ; Remeš, Zdeněk ; Hsu, H.S. ; Rezek, B.
Document type: Papers
Conference/Event: Nanocon 2019 International Conference on Nanomaterials - Research & Application /11./, Brno (CZ), 20191016
Year: 2020
Language: eng
Abstract: Zinc oxide nanoparticles (ZnO NP) have shown great potential as a novel antibacterial material at a time when resistance towards conventional antibiotics is becoming more prevalent. We report bacteria inactivation by ZnO NP with novel hedgehog-like morphology using model gram-negative (E. coli) and gram-positive (S. aureus) bacteria. E. coli exposed to the novel ZnO hedgehog NP during growth resulted in 4 orders of magnitude reduction in viable cell concentration after 24 h, which is more than 2 orders higher reduction compared to commercially available ZnO NPs with nominal sizes from 50 nm to 20 um. There was a positive correlation between hedgehog NP concentration and bacteria cell concentration reduction within the range tested 0.1 – 1.0 mg/mL. S. aureus was less sensitive to ZnO NP exposure and inactivation effect of various ZnO NP, was comparable. The effect can be thus attributed to direct mechanical damage of the bacterial mebrane that is the most effective for the novel hedgehog ZnO NP. This conclusion was corroborated also by disk diffusion assays.\n
Keywords: microbiology; nanotechnology; zinc oxide
Project no.: GC19-02858J (CEP)
Funding provider: GA ČR
Host item entry: Nanocon 2019 : Proceedings of the International Conference on Nanomaterials - Research & Application /11./, ISBN 978-80-87294-95-6
Institution: Institute of Physics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0316924
Permalink: http://www.nusl.cz/ntk/nusl-432392
The record appears in these collections:
Research > Institutes ASCR > Institute of Physics
Conference materials > Papers
Authors: Rutherford, D. ; Jíra, J. ; Mičová, J. ; Remeš, Zdeněk ; Hsu, H.S. ; Rezek, B.
Document type: Papers
Conference/Event: Nanocon 2019 International Conference on Nanomaterials - Research & Application /11./, Brno (CZ), 20191016
Year: 2020
Language: eng
Abstract: Zinc oxide nanoparticles (ZnO NP) have shown great potential as a novel antibacterial material at a time when resistance towards conventional antibiotics is becoming more prevalent. We report bacteria inactivation by ZnO NP with novel hedgehog-like morphology using model gram-negative (E. coli) and gram-positive (S. aureus) bacteria. E. coli exposed to the novel ZnO hedgehog NP during growth resulted in 4 orders of magnitude reduction in viable cell concentration after 24 h, which is more than 2 orders higher reduction compared to commercially available ZnO NPs with nominal sizes from 50 nm to 20 um. There was a positive correlation between hedgehog NP concentration and bacteria cell concentration reduction within the range tested 0.1 – 1.0 mg/mL. S. aureus was less sensitive to ZnO NP exposure and inactivation effect of various ZnO NP, was comparable. The effect can be thus attributed to direct mechanical damage of the bacterial mebrane that is the most effective for the novel hedgehog ZnO NP. This conclusion was corroborated also by disk diffusion assays.\n
Keywords: microbiology; nanotechnology; zinc oxide
Project no.: GC19-02858J (CEP)
Funding provider: GA ČR
Host item entry: Nanocon 2019 : Proceedings of the International Conference on Nanomaterials - Research & Application /11./, ISBN 978-80-87294-95-6
Institution: Institute of Physics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0316924
Permalink: http://www.nusl.cz/ntk/nusl-432392
The record appears in these collections:
Research > Institutes ASCR > Institute of Physics
Conference materials > Papers
Record created 2021-02-24, last modified 2023-06-04