Original title: Exploration of 9-Bromo[7]helicene Reactivity
Authors: Žádný, Jaroslav ; Jakubec, Martin ; Velíšek, Petr ; Sýkora, Jan ; Storch, Jan
Document type: Papers
Conference/Event: 47. konference Pokroky v organické, bioorganické a farmaceutické chemii – Liblice 2012, Lázně Bělohrad (CZ), 2012-11-02 / 2012-11-04
Year: 2012
Language: eng
Abstract: Our new microwave assisted photodehydrocyclisation and completely reviewed synthetic approach for a multi-gram scale production of 9-bromo-[7]helicene led us to explore the reactivity of this compound mainly in Pd-catalysed reactions and to the further functionalization of this molecule. Next to other transformations, palladium catalysed carbon – heteroatom coupling reactions provide a large portfolio of racemic helicenes bearing different functional groups in good to excellent yields. Many of the reactions are performed in the microwave initiator saving reaction time to a minimum comparing with conventional and known synthetic methods. Such prepared compounds can undergo further synthetic reactions or can be used on a field of molecular electronics, surface chemistry or in other applications. The separation of racemic mixtures is under running in our lab. Optically pure compounds of such a type can open new possibilities in their use.
Keywords: helicene; microwave synthesis; palladium cross-coupling
Project no.: GAP207/10/1124 (CEP), FR-TI3/628 (CEP), TA01010646 (CEP)
Funding provider: GA ČR, GA MPO, GA TA ČR
Host item entry: Sborník abstraktů, ISBN N

Institution: Institute of Chemical Process Fundamentals AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0217375

Permalink: http://www.nusl.cz/ntk/nusl-142324


The record appears in these collections:
Research > Institutes ASCR > Institute of Chemical Process Fundamentals
Conference materials > Papers