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A Proposal of New Management Approaches in a Machinery Company
Votruba, Jan ; Häuser, Stanislav (referee) ; Chlebovský, Vít (advisor)
The aim of this thesis is to create a set of recommendations for the selected engineering enterprise. The purpose of these recommendations is to increase the enterprise effectivness and its adaptability quotient. In the first part of this thesis, based on a literature search, the management systems of successful Czech and foreign entrepreneurs are described. In the next part the most appropriate managerial approach is chosen on the basis of the performed qualitative research and this section also describes the current situation of the selected engineering enterprise. In the last part are given individual recommendations and steps to achieve their implementation.
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Transluminace plic - hledání solitárních plicních uzlů pomocí IR záření
Votruba, Jiří ; Drahanský, Martin ; Goldmann, Tomáš
Tento článek obsahuje popis vývoje zařízení s metodikou pro transluminaci plicní tkáně s cílem nalezení solitárních plicních uzlů s minimalizací zátěže pro pacienta. Zařízení na prosvětlování plicní tkáně je založeno na infračerveném světle a bronchoskopu (či trokaru), který umožňuje přenos infračerveného záření po průsvitu tkání do kamery. První pokusy byly provedeny na vepřových plicích ex vivo, pokračovali jsme přes vepřové plíce in vivo, nyní se plánuje testování na pacientech.
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A Proposal of New Management Approaches in a Machinery Company
Votruba, Jan ; Häuser, Stanislav (referee) ; Chlebovský, Vít (advisor)
The aim of this thesis is to create a set of recommendations for the selected engineering enterprise. The purpose of these recommendations is to increase the enterprise effectivness and its adaptability quotient. In the first part of this thesis, based on a literature search, the management systems of successful Czech and foreign entrepreneurs are described. In the next part the most appropriate managerial approach is chosen on the basis of the performed qualitative research and this section also describes the current situation of the selected engineering enterprise. In the last part are given individual recommendations and steps to achieve their implementation.
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New diagnostic methods in bronchology
Votruba, Jiří ; Daneš, Jan (advisor) ; Marel, Miloslav (referee) ; Pešek, Miloš (referee)
The aim of this work has been the development and optimization of methods for early diagnosis of lung cancer, their utility and integration into daily practice. Firstly, we developed a device for measurement of endobronchial temperature (thermobronchoscopy) and found significant difference in endoluminal temperature above tumors and infiltrated lymph nodes compared to healthy regions. We further designed an appliance for near infrared spectroscopy of the bronchial mucosa and identified spectroscopic features useful for localization of solitary pulmonary nodule. The use of the appliance improved yield of endobronchial biopsy compared to endobronchial ultrasound. In the next part of the study, we describe further techniques for early diagnosis of lung cancer including endobronchial ultrasound, optical coherence tomography, confocal fluorescence microendoscopy, reflectance spectroscopy, autofluorescence bronchoscopy, fluorescence bronchoscopy, and narrow band imaging with concise introduction of our experience gained in several pilot projects. Next, we showed the utility of measurement of acetic acid in exhaled air as a promising biomarker for non-invasive identification of patients with symptomatic acid gastroesophageal reflux. Lastly, we demonstrated significant difference in radiation dose in HRCT...
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New diagnostic methods in bronchology
Votruba, Jiří ; Daneš, Jan (advisor) ; Marel, Miloslav (referee) ; Pešek, Miloš (referee)
The aim of this work has been the development and optimization of methods for early diagnosis of lung cancer, their utility and integration into daily practice. Firstly, we developed a device for measurement of endobronchial temperature (thermobronchoscopy) and found significant difference in endoluminal temperature above tumors and infiltrated lymph nodes compared to healthy regions. We further designed an appliance for near infrared spectroscopy of the bronchial mucosa and identified spectroscopic features useful for localization of solitary pulmonary nodule. The use of the appliance improved yield of endobronchial biopsy compared to endobronchial ultrasound. In the next part of the study, we describe further techniques for early diagnosis of lung cancer including endobronchial ultrasound, optical coherence tomography, confocal fluorescence microendoscopy, reflectance spectroscopy, autofluorescence bronchoscopy, fluorescence bronchoscopy, and narrow band imaging with concise introduction of our experience gained in several pilot projects. Next, we showed the utility of measurement of acetic acid in exhaled air as a promising biomarker for non-invasive identification of patients with symptomatic acid gastroesophageal reflux. Lastly, we demonstrated significant difference in radiation dose in HRCT...
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Autofluorescenční spektroskopie plicní tkáně
Votruba, J. ; Zavadil, Jiří ; Javorský, Stanislav ; Kostka, František ; Klimtová, E. ; Brůha, T.
In-vivo investigation of bronchial tissue by autofluorescence (AF) spectroscopy is reported. The study demonstrates differences of both the spectral shape and of signal intensity in photoluminescence spectra emitted from tissue affected by carcinoma as compared to healthy bronchial mucosa. It turns out that point measurements of AF spectra significantly increase the diagnostic utility of the AF method in discrimination of malignant and benign tissue as compared to commercial AF imaging systems.
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Photodynamic therapy. Instrumental optics
Votruba, J. ; Stádník, Bohumil ; Javorský, Stanislav
Photodynamic therapy of cancerous tumorous of various human organs uses both coherent and noncoherent light sources for the treatment. However, noncoherent ones are prefered due to higher treatment efficiency, simpler and reliable operation and lower financial costs. Main purpose of this report is to give overview of basic optical methods and instruments used in the photodynamic therapy.
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