|
|
Options computed tomography with high resolution in the diagnosis pulmonary complications in haematological malignancies
Mírka, Hynek ; Kreuzberg, Boris (advisor) ; Neuwirth, Jiří (referee) ; Heřman, Miroslav (referee)
Value of HRCT in the diagnostics of pulmonary complications of malignant haematologic diseases. Early diagnosis is one of the essential conditions for successful therapy of heamatologic malignancies and their complications. Imaging methods play an important role in their detection and patient's management. HRCT is the most contributing method in the diagnostics of pulmonary involvement, which is very common in this group of patients. The aim of this thesis was to find out the potential of this method in the diagnostics of pulmonary complications in patients with haematologic malignancy. For this purpose were assessed 4 objectives: 1) comparison between HRCT and chest X-ray; 2) determination of capability of HRCT to make a specific diagnose; 3) definition of indication criteria for HRCT and 4) assignment of the suitable examination technique. In the time period from January 2000 until December 2005 were performed 214 HRCT examinations of the lungs in the group of 162 patients with haematological malignancy and pulmonary symptomatology. 176 examinations were compared with chest X-ray, which was performed 48 hours or less before HRCT. Pulmonary lesion was discovered in 180 cases (84,1%). 123 findings were confirmed by another method (response to a specific therapy, cultivation, serology, BAL or...
|
|
|
Use the Contrast-Enhanced Ultrasoun in the Morning of the Effect of Liver Tumors Treatment by Radiofrequency ablation
Korčáková, Eva ; Mírka, Hynek (advisor) ; Mechl, Marek (referee) ; Čtvrtlík, Filip (referee)
Use the contrast-enhanced ultrasound in the monitoring of the effect of liver tumors treatment by radiofrequency ablation. Summary High quality imaging is crucial for the treatment of liver tumors by the percutaneous radiofrequency ablation. Imaging methods are used for planning, navigation of the intervention and monitoring after treatment. An early detection of residual tumor tissue or recurrence affect significantly the quality of life and life expectancy of the patients. Contrast enhanced ultrasound (CEUS) seems to be a suitable method for monitoring the locoregional treatment mainly because zero radiation impact on patient and allows the highly accurate real-time assessment of vascularization. The aim of my work was to verify the ability of CEUS to detect residual tumor tissue or tumor recurrence in the field of changes after radiofrequency ablation. We evaluated the group of 73 patients, who were treated by radiofrequency ablation (RFA) for liver cancer. CEUS reached in our group the overal sensitivity 77.27 %, and in the group of colorectal cancer metastases 83.33 %. We compared CEUS with results of computed tomography (CT), which is the most commonly used method for monitoring the treatment. CEUS and CT results are similar. Based on this study, the CEUS appears to be a suitable method for monitoring...
|
|
|
Use of Imaging Methods in Polytrauma - Patients: Indications and Prognostic Value
Bajcurová, Kristýna ; Mírka, Hynek (advisor) ; Weichet, Jiří (referee) ; Mechl, Marek (referee)
Objective: The possibilities of CT examinations in patients with multiple trauma are: two- phase, or single-phase CT examination. However, a single-phase contrast medium (CM) administration doesn't suffice quality saturation of arteries along with parenchymal organs. My dissertation is focused on a split-bolus contrast medium administration technique. Aim: To prove diagnostic quality of protocols using split-bolus technique. Materials and Methods: Patients were divided into eight groups, namely A to H. After the non-contrast examination of the head and the cervical spine, all patients were examined after CM administration from the skull base to the symphysis. Group A patients underwent a biphasic examination after CM single-bolus, group B patients underwent single-phase examination after a single bolus of CM, and group C-H patients underwent a single-phase examination after split- bolus technique of CM administration. Patients were given 100 ml of CM at the same concentration of 350 mgI/ml. The densities variables in internal carotid arteries, aorta arch, abdominal aorta, common pelvis arteries, liver, v. portae, spleen and kidney were evaluated. The Krusakal-Wallis ANOVA nonparametric statistical method was used to evaluate the variables. The abnormal distribution was found using the Saphiro-Wilk...
|
|
|
Benefits of dynamic contrast ultrasonography for differential diagnosis focal liver lesions
Ungermann, Leoš ; Eliáš, Pavel (advisor) ; Mechl, Marek (referee) ; Mírka, Hynek (referee)
5 3. Summary Purpose: To evaluate the clinical utility of contrast enhanced ultrasonography (CEUS) for the characterisation of focal liver lesions with the emphasis on the benign entities. Our aim was to find out the accuracy of CEUS to differentiate between the malignant and benign lesions and to extend the knowledge about the typical signs of solid benignomas on CEUS. Material and methods: our material consists of 163 liver masses observed in 144 patients. The final dianosis has been stated by means of the computed tomography in 26.4 %, magnetic resonance imaging (60.4 %) and histology (25.8 %). There was a majority of women (n=90) against men (n=54); the average age was 47.6 years. The number of benign lesions (n=137) markedly exceeded the number of malignant ones (n=6). The dominant lesions were hemangiomas (n=66), the second most common was focal nodular hyperplasia (FNH, n=42). The other lesions comprised of limited numbers of entities(focal steatotic or nonsteatis regions: n=21, metastatic lesions: n=15, hepatocelullar carcinoma, n=7, regenerative nodular hyperplasia, n=5, peripheral cholangiogenic carcinoma, n=4, and others - inflemmatory pseudotumour, adenoma, epithelial angiomyolipoma). Results: The accuracy of CEUS for the differentiation of malign or benign lesion was 95, 7 %. Regarding the...
|
|
|
Options computed tomography with high resolution in the diagnosis pulmonary complications in haematological malignancies
Mírka, Hynek ; Kreuzberg, Boris (advisor) ; Neuwirth, Jiří (referee) ; Heřman, Miroslav (referee)
Value of HRCT in the diagnostics of pulmonary complications of malignant haematologic diseases. Early diagnosis is one of the essential conditions for successful therapy of heamatologic malignancies and their complications. Imaging methods play an important role in their detection and patient's management. HRCT is the most contributing method in the diagnostics of pulmonary involvement, which is very common in this group of patients. The aim of this thesis was to find out the potential of this method in the diagnostics of pulmonary complications in patients with haematologic malignancy. For this purpose were assessed 4 objectives: 1) comparison between HRCT and chest X-ray; 2) determination of capability of HRCT to make a specific diagnose; 3) definition of indication criteria for HRCT and 4) assignment of the suitable examination technique. In the time period from January 2000 until December 2005 were performed 214 HRCT examinations of the lungs in the group of 162 patients with haematological malignancy and pulmonary symptomatology. 176 examinations were compared with chest X-ray, which was performed 48 hours or less before HRCT. Pulmonary lesion was discovered in 180 cases (84,1%). 123 findings were confirmed by another method (response to a specific therapy, cultivation, serology, BAL or...
|
guest ::
